Reviewed,
UniProtKB/Swiss-Prot Q9CQ60 (6PGL_MOUSE)
Last modified
November 3, 2009.
Version 60.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: 6-phosphogluconolactonase Short name=6PGL EC=3.1.1.31 | ||
| Gene names |
| ||
| Organism | Mus musculus (Mouse) | ||
| Taxonomic identifier | 10090 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus |
Protein attributes
| Sequence length | 257 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity. |
| Catalytic activity | 6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate. |
| Pathway | |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Molecular function | Hydrolase |
| PTM | Acetylation |
| Gene Ontology (GO) | |
| Biological process | pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro |
| Molecular function | 6-phosphogluconolactonase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. Hayashizaki Y.Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6J and NOD. Tissue: Heart and Spleen. |
| [2] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: FVB/N. Tissue: Mammary tumor. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| AK003134 mRNA. Translation: BAB22594.1. AK003985 mRNA. Translation: BAB23106.1. AK172066 mRNA. Translation: BAE42808.1. BC006594 mRNA. Translation: AAH06594.1. | |
| IPI | IPI00132080. |
| RefSeq | NP_079672.1. |
| UniGene | Mm.282284 Mm.402679 |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q9CQ60. |
2-D gel databases | |
| REPRODUCTION-2DPAGE | Q9CQ60. |
Proteomic databases | |
| PRIDE | Q9CQ60. |
Genome annotation databases | |
| Ensembl | ENSMUST00000034264; ENSMUSP00000034264; ENSMUSG00000031807; Mus musculus. [Genome view] |
| GeneID | 66171. |
| KEGG | mmu:66171. |
| NMPDR | fig|10090.3.peg.18720. |
| UCSC | uc009meb.1. mouse. |
Organism-specific databases | |
| CTD | 66171. |
| MGI | MGI:1913421. Pgls. |
Phylogenomic databases | |
| HOGENOM | Q9CQ60. |
| HOVERGEN | Q9CQ60. |
| OMA | LYQPAAS. |
Enzyme and pathway databases | |
| BRENDA | 3.1.1.31. 244. |
Gene expression databases | |
| ArrayExpress | Q9CQ60. |
| Bgee | Q9CQ60. |
| CleanEx | MM_PGLS. |
| Genevestigator | Q9CQ60. |
| GermOnline | ENSMUSG00000031807. Mus musculus. |
Family and domain databases | |
| InterPro | IPR005900. 6-phosphogluconolactonase. IPR006148. Glc/Gal-6P_isomerase. [Graphical view] |
| PANTHER | PTHR11054. Phosphogluconlac. 1 hit. |
| Pfam | PF01182. Glucosamine_iso. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR01198. pgl. 1 hit. |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 320850. |
| SOURCE | Search... |
Entry information
| Entry name | 6PGL_MOUSE | ||||||||
| Accession | Primary (citable) accession number: Q9CQ60 Secondary accession number(s): Q3TA62 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HPI (Human Proteome Initiative) | ||||||||
Relevant documents
| MGD cross-references Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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