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Protein

39S ribosomal protein L49, mitochondrial

Gene

Mrpl49

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L49, mitochondrial
Short name:
L49mt
Short name:
MRP-L49
Gene namesi
Name:Mrpl49
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:108180 Mrpl49

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002076661 – 16639S ribosomal protein L49, mitochondrialAdd BLAST166

Proteomic databases

EPDiQ9CQ40
MaxQBiQ9CQ40
PaxDbiQ9CQ40
PeptideAtlasiQ9CQ40
PRIDEiQ9CQ40

PTM databases

PhosphoSitePlusiQ9CQ40

Expressioni

Gene expression databases

BgeeiENSMUSG00000007338
CleanExiMM_MRPL49
GenevisibleiQ9CQ40 MM

Interactioni

Subunit structurei

Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins (By similarity). Interacts with OXA1L (By similarity).By similarity

Protein-protein interaction databases

BioGridi201802, 1 interactor
STRINGi10090.ENSMUSP00000007482

Structurei

3D structure databases

ProteinModelPortaliQ9CQ40
SMRiQ9CQ40
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG4034 Eukaryota
ENOG4111N34 LUCA
GeneTreeiENSGT00390000017253
HOGENOMiHOG000044600
HOVERGENiHBG023124
InParanoidiQ9CQ40
KOiK17430
OMAiKPPKHEH
OrthoDBiEOG091G1549
PhylomeDBiQ9CQ40
TreeFamiTF317750

Family and domain databases

InterProiView protein in InterPro
IPR007740 Ribosomal_L49/IMG2
PANTHERiPTHR13477 PTHR13477, 1 hit
PfamiView protein in Pfam
PF05046 Img2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9CQ40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAAVLRAAL QDWRSCLGRS YGRRKLSQTQ GPPDNPGFVE SVDEYQFVER
60 70 80 90 100
LLPPTKIPEP PKHKHYPTPS GWQPPRDPLP SLPYFVRRSR MHNIPVYKEI
110 120 130 140 150
THGNRQMTLI RKVEGDIWAL QKDVEEFLSP LLGKTPITQV NEVTGTLRIK
160
GYFDEQLKAW LLEKGF
Length:166
Mass (Da):19,133
Last modified:June 1, 2001 - v1
Checksum:iCCF652F8403DA229
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti152Y → N in BAC33922 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK007712 mRNA Translation: BAB25205.1
AK014723 mRNA Translation: BAB29520.1
AK027949 mRNA Translation: BAC25678.1
AK049794 mRNA Translation: BAC33922.1
AK077397 mRNA Translation: BAC36782.1
AK150572 mRNA Translation: BAE29667.1
AK150715 mRNA Translation: BAE29793.1
BC028956 mRNA Translation: AAH28956.1
CCDSiCCDS29488.1
RefSeqiNP_080522.1, NM_026246.3
UniGeneiMm.181290

Genome annotation databases

EnsembliENSMUST00000007482; ENSMUSP00000007482; ENSMUSG00000007338
GeneIDi18120
KEGGimmu:18120
UCSCiuc008ggq.1 mouse

Similar proteinsi

Entry informationi

Entry nameiRM49_MOUSE
AccessioniPrimary (citable) accession number: Q9CQ40
Secondary accession number(s): Q3UC21, Q8C5R0, Q8C7P3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: June 1, 2001
Last modified: May 23, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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