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Protein

39S ribosomal protein L24, mitochondrial

Gene

Mrpl24

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840. Mitochondrial translation elongation.
R-MMU-5419276. Mitochondrial translation termination.

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L24, mitochondrial
Short name:
L24mt
Short name:
MRP-L24
Gene namesi
Name:Mrpl24
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1914957. Mrpl24.

Subcellular locationi

  • Mitochondrion By similarity

GO - Cellular componenti

  • mitochondrial large ribosomal subunit Source: UniProtKB
  • mitochondrion Source: MGI

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 9MitochondrionBy similarity9
ChainiPRO_000027048910 – 21639S ribosomal protein L24, mitochondrialAdd BLAST207

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei24PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9CQ06.
MaxQBiQ9CQ06.
PaxDbiQ9CQ06.
PeptideAtlasiQ9CQ06.
PRIDEiQ9CQ06.

PTM databases

iPTMnetiQ9CQ06.
PhosphoSitePlusiQ9CQ06.

Expressioni

Gene expression databases

BgeeiENSMUSG00000019710.
CleanExiMM_MRPL24.
ExpressionAtlasiQ9CQ06. baseline and differential.
GenevisibleiQ9CQ06. MM.

Interactioni

Subunit structurei

Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000019854.

Structurei

3D structure databases

ProteinModelPortaliQ9CQ06.
SMRiQ9CQ06.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini56 – 89KOWAdd BLAST34

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG1708. Eukaryota.
COG0198. LUCA.
GeneTreeiENSGT00390000014542.
HOGENOMiHOG000031326.
HOVERGENiHBG093899.
InParanoidiQ9CQ06.
KOiK02895.
OMAiPAKSYWY.
OrthoDBiEOG091G0EA2.
PhylomeDBiQ9CQ06.
TreeFamiTF105984.

Family and domain databases

Gene3Di2.30.30.30. 1 hit.
HAMAPiMF_01326_B. Ribosomal_L24_B. 1 hit.
InterProiView protein in InterPro
IPR005824. KOW.
IPR014722. Rib_L2_dom2.
IPR003256. Ribosomal_L24.
IPR005825. Ribosomal_L24/26_CS.
IPR008991. Translation_prot_SH3-like.
PfamiView protein in Pfam
PF00467. KOW. 1 hit.
PF17136. ribosomal_L24. 1 hit.
SMARTiView protein in SMART
SM00739. KOW. 1 hit.
SUPFAMiSSF50104. SSF50104. 1 hit.
TIGRFAMsiTIGR01079. rplX_bact. 1 hit.
PROSITEiView protein in PROSITE
PS01108. RIBOSOMAL_L24. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9CQ06-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLSALLALA SKATSSPFYR YGMSRPGSIA DKRKNPPWSR RRPVVVEPIS
60 70 80 90 100
DEDWHLFCGD MVEILEGKDA GKQGKVVQVV RQRNWVVLEG LNTHYRYIGR
110 120 130 140 150
TKDHRGTMIA SEAPLLHHQV KLVDPVDRKP TEIQWRFTEA GERVRVSTRS
160 170 180 190 200
GRIIPKPEFP RADGIVPETW TDGPKDTSVE DALERTYVPR LKTLEEDVME
210
AMGIQETRRF KKVYWY
Length:216
Mass (Da):24,945
Last modified:June 1, 2001 - v1
Checksum:iDE869E7630AF599F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti7 – 9LAL → FAS in BAB25991 (PubMed:16141072).Curated3
Sequence conflicti14 – 15TS → IC in BAB25991 (PubMed:16141072).Curated2
Sequence conflicti26 – 27PG → RS in BAB25991 (PubMed:16141072).Curated2
Sequence conflicti30A → G in BAB25991 (PubMed:16141072).Curated1
Sequence conflicti34K → Q in BAB25991 (PubMed:16141072).Curated1
Sequence conflicti42R → L in BAB22737 (PubMed:16141072).Curated1
Sequence conflicti48P → A in BAB25991 (PubMed:16141072).Curated1
Sequence conflicti116L → F in BAB32014 (PubMed:16141072).Curated1
Sequence conflicti143R → L in BAB22737 (PubMed:16141072).Curated1
Sequence conflicti177T → I in BAB32014 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003362 mRNA. Translation: BAB22737.1.
AK008117 mRNA. Translation: BAB25472.1.
AK008961 mRNA. Translation: BAB25991.1.
AK013394 mRNA. Translation: BAB28828.1.
AK019976 mRNA. Translation: BAB31945.1.
AK020157 mRNA. Translation: BAB32014.1.
AK167623 mRNA. Translation: BAE39675.1.
BC004736 mRNA. Translation: AAH04736.1.
BC025506 mRNA. Translation: AAH25506.1.
BC031730 mRNA. Translation: AAH31730.1.
CCDSiCCDS38477.1.
RefSeqiNP_080867.2. NM_026591.3.
XP_006502003.1. XM_006501940.2.
XP_006502004.1. XM_006501941.3.
XP_006502005.1. XM_006501942.3.
UniGeneiMm.393802.

Genome annotation databases

EnsembliENSMUST00000019854; ENSMUSP00000019854; ENSMUSG00000019710.
ENSMUST00000119968; ENSMUSP00000114111; ENSMUSG00000019710.
ENSMUST00000121048; ENSMUSP00000113959; ENSMUSG00000019710.
ENSMUST00000121920; ENSMUSP00000112885; ENSMUSG00000019710.
GeneIDi67707.
KEGGimmu:67707.
UCSCiuc008ptd.1. mouse.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRM24_MOUSE
AccessioniPrimary (citable) accession number: Q9CQ06
Secondary accession number(s): Q9CX51, Q9D1L7, Q9D7R6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: June 1, 2001
Last modified: June 7, 2017
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families