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Protein

Cyclin-dependent kinase 2-associated protein 2

Gene

Cdk2ap2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinase 2-associated protein 2
Short name:
CDK2-associated protein 2
Alternative name(s):
DOC-1-related protein
Short name:
DOC-1R
Gene namesi
Name:Cdk2ap2
Synonyms:D19Ertd144e, Doc1r
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:1098779. Cdk2ap2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 127127Cyclin-dependent kinase 2-associated protein 2PRO_0000079964Add
BLAST

Proteomic databases

EPDiQ9CPY4.
MaxQBiQ9CPY4.
PaxDbiQ9CPY4.
PeptideAtlasiQ9CPY4.
PRIDEiQ9CPY4.

PTM databases

iPTMnetiQ9CPY4.
PhosphoSiteiQ9CPY4.

Expressioni

Gene expression databases

BgeeiQ9CPY4.
CleanExiMM_CDK2AP2.
ExpressionAtlasiQ9CPY4. baseline and differential.
GenevisibleiQ9CPY4. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025779.

Structurei

3D structure databases

ProteinModelPortaliQ9CPY4.
SMRiQ9CPY4. Positions 62-127.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CDK2AP family.Curated

Phylogenomic databases

eggNOGiKOG4713. Eukaryota.
ENOG41126TJ. LUCA.
GeneTreeiENSGT00390000006964.
HOGENOMiHOG000035115.
HOVERGENiHBG002074.
InParanoidiQ9CPY4.
OMAiMKPPGTQ.
OrthoDBiEOG71RXN6.
PhylomeDBiQ9CPY4.
TreeFamiTF101037.

Family and domain databases

InterProiIPR017266. CDK2-associated_2.
IPR019187. Cyclin-dep_kinase2-assoc_pr.
[Graphical view]
PfamiPF09806. CDK2AP. 1 hit.
[Graphical view]
PIRSFiPIRSF037709. CDK2-associated_p2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9CPY4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYKPIAPAP SSTPGSSTPG PGTPVPTAGS VPSPSGSVPG AAAPFRPLFN
60 70 80 90 100
DFGPPSMGYV QAMKPPGSQG SQSTYTDLLS VIEEMGKEIR PTYAGSKSAM
110 120
ERLKRGIIHA RALVRECLAE TERNART
Length:127
Mass (Da):13,202
Last modified:June 1, 2001 - v1
Checksum:iE8299A37B030EEFD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003686 mRNA. Translation: BAB22939.1.
AK012121 mRNA. Translation: BAB28046.1.
AK018035 mRNA. Translation: BAB31046.1.
BC025656 mRNA. Translation: AAH25656.1.
CCDSiCCDS29414.1.
RefSeqiNP_080649.1. NM_026373.4.
UniGeneiMm.29609.

Genome annotation databases

EnsembliENSMUST00000025779; ENSMUSP00000025779; ENSMUSG00000024856.
ENSMUST00000180435; ENSMUSP00000137712; ENSMUSG00000097485.
GeneIDi52004.
KEGGimmu:52004.
UCSCiuc008fym.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003686 mRNA. Translation: BAB22939.1.
AK012121 mRNA. Translation: BAB28046.1.
AK018035 mRNA. Translation: BAB31046.1.
BC025656 mRNA. Translation: AAH25656.1.
CCDSiCCDS29414.1.
RefSeqiNP_080649.1. NM_026373.4.
UniGeneiMm.29609.

3D structure databases

ProteinModelPortaliQ9CPY4.
SMRiQ9CPY4. Positions 62-127.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025779.

PTM databases

iPTMnetiQ9CPY4.
PhosphoSiteiQ9CPY4.

Proteomic databases

EPDiQ9CPY4.
MaxQBiQ9CPY4.
PaxDbiQ9CPY4.
PeptideAtlasiQ9CPY4.
PRIDEiQ9CPY4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000025779; ENSMUSP00000025779; ENSMUSG00000024856.
ENSMUST00000180435; ENSMUSP00000137712; ENSMUSG00000097485.
GeneIDi52004.
KEGGimmu:52004.
UCSCiuc008fym.1. mouse.

Organism-specific databases

CTDi10263.
MGIiMGI:1098779. Cdk2ap2.

Phylogenomic databases

eggNOGiKOG4713. Eukaryota.
ENOG41126TJ. LUCA.
GeneTreeiENSGT00390000006964.
HOGENOMiHOG000035115.
HOVERGENiHBG002074.
InParanoidiQ9CPY4.
OMAiMKPPGTQ.
OrthoDBiEOG71RXN6.
PhylomeDBiQ9CPY4.
TreeFamiTF101037.

Miscellaneous databases

PROiQ9CPY4.
SOURCEiSearch...

Gene expression databases

BgeeiQ9CPY4.
CleanExiMM_CDK2AP2.
ExpressionAtlasiQ9CPY4. baseline and differential.
GenevisibleiQ9CPY4. MM.

Family and domain databases

InterProiIPR017266. CDK2-associated_2.
IPR019187. Cyclin-dep_kinase2-assoc_pr.
[Graphical view]
PfamiPF09806. CDK2AP. 1 hit.
[Graphical view]
PIRSFiPIRSF037709. CDK2-associated_p2. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Embryo and Thymus.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/N.
    Tissue: Mammary tumor.

Entry informationi

Entry nameiCDKA2_MOUSE
AccessioniPrimary (citable) accession number: Q9CPY4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: June 1, 2001
Last modified: July 6, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.