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Protein

Cytochrome b-c1 complex subunit 10

Gene

Uqcr11

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain.By similarity
This protein may be closely linked to the iron-sulfur protein in the complex and function as an iron-sulfur protein binding factor.By similarity

GO - Molecular functioni

  • ubiquinol-cytochrome-c reductase activity Source: MGI

Keywordsi

Biological processElectron transport, Respiratory chain, Transport

Enzyme and pathway databases

ReactomeiR-MMU-611105 Respiratory electron transport

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome b-c1 complex subunit 10
Alternative name(s):
Complex III subunit 10
Complex III subunit XI
Ubiquinol-cytochrome c reductase complex 6.4 kDa protein
Gene namesi
Name:Uqcr11
Synonyms:Uqcr
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1913844 Uqcr11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei16 – 36HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001935611 – 56Cytochrome b-c1 complex subunit 10Add BLAST56

Proteomic databases

EPDiQ9CPX8
MaxQBiQ9CPX8
PaxDbiQ9CPX8
PRIDEiQ9CPX8
TopDownProteomicsiQ9CPX8

Expressioni

Gene expression databases

BgeeiENSMUSG00000020163
CleanExiMM_UQCR
GenevisibleiQ9CPX8 MM

Interactioni

Subunit structurei

The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1).By similarity

Protein-protein interaction databases

CORUMiQ9CPX8
STRINGi10090.ENSMUSP00000020372

Structurei

3D structure databases

ProteinModelPortaliQ9CPX8
SMRiQ9CPX8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UQCR11/QCR10 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J5Z0 Eukaryota
ENOG410XVMI LUCA
GeneTreeiENSGT00390000018299
HOGENOMiHOG000030914
HOVERGENiHBG105467
InParanoidiQ9CPX8
KOiK00420
OMAiGMWGAVG
OrthoDBiEOG091G1ATB
PhylomeDBiQ9CPX8
TreeFamiTF105034

Family and domain databases

InterProiView protein in InterPro
IPR029027 Single_a-helix_sf
IPR015089 UQCR
PANTHERiPTHR15420 PTHR15420, 1 hit
PfamiView protein in Pfam
PF08997 UCR_6-4kD, 1 hit
SUPFAMiSSF81518 SSF81518, 1 hit

Sequencei

Sequence statusi: Complete.

Q9CPX8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSRFLGPRY RELARNWIPT AGMWGTVGAV GLVWATDWRL ILDWVPYING

KFKKDD
Length:56
Mass (Da):6,539
Last modified:June 1, 2001 - v1
Checksum:iEAF75D79D41B5713
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003033 mRNA Translation: BAB22521.1
AK003443 mRNA Translation: BAB22793.1
AK013513 mRNA Translation: BAB28890.1
AK167946 mRNA Translation: BAE39949.1
AK168974 mRNA Translation: BAE40777.1
BC034408 mRNA Translation: AAH34408.1
CCDSiCCDS35981.1
RefSeqiNP_079926.1, NM_025650.2
UniGeneiMm.379119

Genome annotation databases

EnsembliENSMUST00000020372; ENSMUSP00000020372; ENSMUSG00000020163
GeneIDi66594
KEGGimmu:66594
UCSCiuc007gde.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQCR10_MOUSE
AccessioniPrimary (citable) accession number: Q9CPX8
Secondary accession number(s): Q3TFX1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: June 1, 2001
Last modified: February 28, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health