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Protein

Cytochrome b-c1 complex subunit 10

Gene

Uqcr11

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain.By similarity
This protein may be closely linked to the iron-sulfur protein in the complex and function as an iron-sulfur protein binding factor.By similarity

GO - Molecular functioni

  • electron carrier activity Source: InterPro
  • ubiquinol-cytochrome-c reductase activity Source: MGI

Keywordsi

Biological processElectron transport, Respiratory chain, Transport

Enzyme and pathway databases

ReactomeiR-MMU-611105. Respiratory electron transport.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome b-c1 complex subunit 10
Alternative name(s):
Complex III subunit 10
Complex III subunit XI
Ubiquinol-cytochrome c reductase complex 6.4 kDa protein
Gene namesi
Name:Uqcr11
Synonyms:Uqcr
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1913844. Uqcr11.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei16 – 36HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001935611 – 56Cytochrome b-c1 complex subunit 10Add BLAST56

Proteomic databases

EPDiQ9CPX8.
MaxQBiQ9CPX8.
PaxDbiQ9CPX8.
PRIDEiQ9CPX8.
TopDownProteomicsiQ9CPX8.

Expressioni

Gene expression databases

BgeeiENSMUSG00000020163.
CleanExiMM_UQCR.
GenevisibleiQ9CPX8. MM.

Interactioni

Subunit structurei

The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1).By similarity

Protein-protein interaction databases

CORUMiQ9CPX8.
STRINGi10090.ENSMUSP00000020372.

Structurei

3D structure databases

ProteinModelPortaliQ9CPX8.
SMRiQ9CPX8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UQCR11/QCR10 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J5Z0. Eukaryota.
ENOG410XVMI. LUCA.
GeneTreeiENSGT00390000018299.
HOGENOMiHOG000030914.
HOVERGENiHBG105467.
InParanoidiQ9CPX8.
KOiK00420.
OMAiGMWGAVG.
OrthoDBiEOG091G1ATB.
PhylomeDBiQ9CPX8.
TreeFamiTF105034.

Family and domain databases

Gene3Di1.20.5.220. 1 hit.
InterProiView protein in InterPro
IPR029027. Single_a-helix.
IPR015089. UQCR.
PANTHERiPTHR15420. PTHR15420. 1 hit.
PfamiView protein in Pfam
PF08997. UCR_6-4kD. 1 hit.
SUPFAMiSSF81518. SSF81518. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9CPX8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSRFLGPRY RELARNWIPT AGMWGTVGAV GLVWATDWRL ILDWVPYING

KFKKDD
Length:56
Mass (Da):6,539
Last modified:June 1, 2001 - v1
Checksum:iEAF75D79D41B5713
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003033 mRNA. Translation: BAB22521.1.
AK003443 mRNA. Translation: BAB22793.1.
AK013513 mRNA. Translation: BAB28890.1.
AK167946 mRNA. Translation: BAE39949.1.
AK168974 mRNA. Translation: BAE40777.1.
BC034408 mRNA. Translation: AAH34408.1.
CCDSiCCDS35981.1.
RefSeqiNP_079926.1. NM_025650.2.
UniGeneiMm.379119.

Genome annotation databases

EnsembliENSMUST00000020372; ENSMUSP00000020372; ENSMUSG00000020163.
GeneIDi66594.
KEGGimmu:66594.
UCSCiuc007gde.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiQCR10_MOUSE
AccessioniPrimary (citable) accession number: Q9CPX8
Secondary accession number(s): Q3TFX1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: June 1, 2001
Last modified: October 25, 2017
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families