ID   RT16_MOUSE              Reviewed;         135 AA.
AC   Q9CPX7;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   27-APR-2001, sequence version 1.
DT   27-MAR-2024, entry version 158.
DE   RecName: Full=Small ribosomal subunit protein bS16m {ECO:0000305};
DE   AltName: Full=28S ribosomal protein S16, mitochondrial;
DE            Short=MRP-S16;
DE            Short=S16mt;
DE   Flags: Precursor;
GN   Name=Mrps16; Synonyms=Rpms16;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=11402041; DOI=10.1074/jbc.m103236200;
RA   Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A.,
RA   Watanabe K.;
RT   "Proteomic analysis of the mammalian mitochondrial ribosome. Identification
RT   of protein components in the 28S small subunit.";
RL   J. Biol. Chem. 276:33181-33195(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Cerebellum, and Embryo;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Mammary tumor;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [4]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Brown adipose tissue, Heart, Kidney, Liver, and Testis;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC       which comprises a 12S rRNA and about 30 distinct proteins.
CC       {ECO:0000250|UniProtKB:Q9Y3D3}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9Y3D3}.
CC   -!- SIMILARITY: Belongs to the bacterial ribosomal protein bS16 family.
CC       {ECO:0000305}.
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DR   EMBL; AB049949; BAB41002.1; -; mRNA.
DR   EMBL; AK019243; BAB31623.1; -; mRNA.
DR   EMBL; AK005206; BAB23884.1; -; mRNA.
DR   EMBL; BC024656; AAH24656.1; -; mRNA.
DR   CCDS; CCDS36817.1; -.
DR   RefSeq; NP_079716.1; NM_025440.2.
DR   PDB; 7PNT; EM; 3.19 A; M=1-135.
DR   PDB; 7PNU; EM; 3.06 A; M=1-135.
DR   PDB; 7PNV; EM; 3.06 A; M=1-135.
DR   PDB; 7PNW; EM; 3.09 A; M=1-135.
DR   PDBsum; 7PNT; -.
DR   PDBsum; 7PNU; -.
DR   PDBsum; 7PNV; -.
DR   PDBsum; 7PNW; -.
DR   AlphaFoldDB; Q9CPX7; -.
DR   EMDB; EMD-13551; -.
DR   EMDB; EMD-13552; -.
DR   EMDB; EMD-13553; -.
DR   EMDB; EMD-13554; -.
DR   SMR; Q9CPX7; -.
DR   BioGRID; 211321; 2.
DR   ComplexPortal; CPX-5301; 28S mitochondrial small ribosomal subunit.
DR   STRING; 10090.ENSMUSP00000055619; -.
DR   PhosphoSitePlus; Q9CPX7; -.
DR   SwissPalm; Q9CPX7; -.
DR   EPD; Q9CPX7; -.
DR   MaxQB; Q9CPX7; -.
DR   PaxDb; 10090-ENSMUSP00000055619; -.
DR   PeptideAtlas; Q9CPX7; -.
DR   ProteomicsDB; 257046; -.
DR   Pumba; Q9CPX7; -.
DR   Antibodypedia; 45368; 149 antibodies from 23 providers.
DR   DNASU; 66242; -.
DR   Ensembl; ENSMUST00000061444.5; ENSMUSP00000055619.4; ENSMUSG00000049960.5.
DR   GeneID; 66242; -.
DR   KEGG; mmu:66242; -.
DR   UCSC; uc007sjp.1; mouse.
DR   AGR; MGI:1913492; -.
DR   CTD; 51021; -.
DR   MGI; MGI:1913492; Mrps16.
DR   VEuPathDB; HostDB:ENSMUSG00000049960; -.
DR   eggNOG; KOG3419; Eukaryota.
DR   GeneTree; ENSGT00390000014309; -.
DR   HOGENOM; CLU_100590_4_0_1; -.
DR   InParanoid; Q9CPX7; -.
DR   OMA; PNDYNER; -.
DR   OrthoDB; 4949030at2759; -.
DR   PhylomeDB; Q9CPX7; -.
DR   TreeFam; TF105637; -.
DR   Reactome; R-MMU-5389840; Mitochondrial translation elongation.
DR   Reactome; R-MMU-5419276; Mitochondrial translation termination.
DR   BioGRID-ORCS; 66242; 23 hits in 76 CRISPR screens.
DR   ChiTaRS; Mrps16; mouse.
DR   PRO; PR:Q9CPX7; -.
DR   Proteomes; UP000000589; Chromosome 14.
DR   RNAct; Q9CPX7; Protein.
DR   Bgee; ENSMUSG00000049960; Expressed in digastric muscle group and 253 other cell types or tissues.
DR   GO; GO:0005829; C:cytosol; ISO:MGI.
DR   GO; GO:0005743; C:mitochondrial inner membrane; NAS:ComplexPortal.
DR   GO; GO:0005763; C:mitochondrial small ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISS:UniProtKB.
DR   GO; GO:0032543; P:mitochondrial translation; ISS:UniProtKB.
DR   Gene3D; 3.30.1320.10; -; 1.
DR   HAMAP; MF_00385; Ribosomal_bS16; 1.
DR   InterPro; IPR000307; Ribosomal_bS16.
DR   InterPro; IPR023803; Ribosomal_bS16_dom_sf.
DR   NCBIfam; TIGR00002; S16; 1.
DR   PANTHER; PTHR12919:SF39; 28S RIBOSOMAL PROTEIN S16, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR12919; 30S RIBOSOMAL PROTEIN S16; 1.
DR   Pfam; PF00886; Ribosomal_S16; 1.
DR   SUPFAM; SSF54565; Ribosomal protein S16; 1.
DR   Genevisible; Q9CPX7; MM.
PE   1: Evidence at protein level;
KW   3D-structure; Mitochondrion; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein; Transit peptide.
FT   TRANSIT         1..34
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           35..135
FT                   /note="Small ribosomal subunit protein bS16m"
FT                   /id="PRO_0000030619"
SQ   SEQUENCE   135 AA;  15192 MW;  EBA2A7209177B50C CRC64;
     MVQLTTIFCK AYHGGHLTIR LALGGCTNRP FYRIVAAHNK CPRDGRFVEQ LGSYDPLPNS
     HGEKLVALNL DRIRHWIGCG AHLSKPMEKL LGLSGFFPLH PMMITNAERL RRRRAREVLL
     ASQKAESEAK ETEAS
//