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Protein

Ferritin

Gene

Ftl1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processIron storageUniRule annotationSAAS annotation
LigandIron, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-MMU-432722 Golgi Associated Vesicle Biogenesis
R-MMU-6798695 Neutrophil degranulation
R-MMU-917937 Iron uptake and transport

Names & Taxonomyi

Protein namesi
Recommended name:
FerritinUniRule annotation
Gene namesi
Name:Ftl1Imported
Synonyms:Ftl1-ps1Imported
ORF Names:mCG_17237Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:95589 Ftl1
MGI:3779109 Ftl1-ps1

Subcellular locationi

PTM / Processingi

Proteomic databases

TopDownProteomicsiQ9CPX4

Expressioni

Gene expression databases

BgeeiENSMUSG00000050708

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 156Ferritin-like diironInterPro annotationAdd BLAST150

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili53 – 73Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the ferritin family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2332 Eukaryota
COG1528 LUCA
GeneTreeiENSGT00760000119129
HOVERGENiHBG000410
KOiK13625
OMAiVNLYLRA
OrthoDBiEOG091G0J20
TreeFamiTF313885

Family and domain databases

Gene3Di1.20.1260.101 hit
InterProiView protein in InterPro
IPR001519 Ferritin
IPR012347 Ferritin-like
IPR009040 Ferritin-like_diiron
IPR009078 Ferritin-like_SF
IPR014034 Ferritin_CS
IPR008331 Ferritin_DPS_dom
PANTHERiPTHR11431 PTHR11431, 1 hit
PfamiView protein in Pfam
PF00210 Ferritin, 1 hit
SUPFAMiSSF47240 SSF47240, 1 hit
PROSITEiView protein in PROSITE
PS00540 FERRITIN_1, 1 hit
PS00204 FERRITIN_2, 1 hit
PS50905 FERRITIN_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

Q9CPX4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSQIRQNYS TEVEAAVNRL VNLHLRASYT YLSLGFFFDR DDVALEGVGH
60 70 80 90 100
FFRELAEEKR EGAERLLEFQ NDRGGRALFQ DVQKPSQDEW GKTQEAMEAA
110 120 130 140 150
LAMEKNLNQA LLDLHALGSA RADPHLCDFL ESHYLDKEVK LIKKMGNHLT
160 170 180
NLRRVAGPQP AQTGAPQGSL GEYLFERLTL KHD
Length:183
Mass (Da):20,772
Last modified:June 1, 2001 - v1
Checksum:iED39E8CCBABA590B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC151602 Genomic DNA No translation available.
CT009486 Genomic DNA No translation available.
BC081462 mRNA Translation: AAH81462.1
BC083350 mRNA Translation: AAH83350.1
BC085309 mRNA Translation: AAH85309.1
BC092259 mRNA Translation: AAH92259.1
BC106146 mRNA Translation: AAI06147.1
AK002242 mRNA Translation: BAB21959.1
AK002253 mRNA Translation: BAB21967.1
AK011009 mRNA Translation: BAB27328.1
AK011029 mRNA Translation: BAB27345.1
AK011244 mRNA Translation: BAB27491.1
AK088647 mRNA Translation: BAC40475.1
AK150480 mRNA Translation: BAE29596.1
AK151255 mRNA Translation: BAE30244.1
AK152030 mRNA Translation: BAE30889.1
AK152385 mRNA Translation: BAE31173.1
AK152393 mRNA Translation: BAE31181.1
AK152564 mRNA Translation: BAE31317.1
AK152612 mRNA Translation: BAE31357.1
AK159574 mRNA Translation: BAE35195.1
AK168735 mRNA Translation: BAE40576.1
AK168862 mRNA Translation: BAE40681.1
AK168866 mRNA Translation: BAE40685.1
AK169100 mRNA Translation: BAE40883.1
AK169159 mRNA Translation: BAE40938.1
CH466563 Genomic DNA Translation: EDL37096.1
CH466563 Genomic DNA Translation: EDL37097.1
RefSeqiNP_034370.2, NM_010240.2
XP_003689256.2, XM_003689208.3
UniGeneiMm.30357
Mm.348374
Mm.431913
Mm.491102

Genome annotation databases

EnsembliENSMUST00000094434; ENSMUSP00000092002; ENSMUSG00000050708
ENSMUST00000222435; ENSMUSP00000152609; ENSMUSG00000062382
GeneIDi100862446
14325
KEGGimmu:100862446
mmu:14325
UCSCiuc009gvf.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ9CPX4_MOUSE
AccessioniPrimary (citable) accession number: Q9CPX4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: April 25, 2018
This is version 154 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported