Q9CPX4 (Q9CPX4_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Ferritin RuleBase RU000622

Gene names

Name:	Ftl1 Ensembl ENSMUSP00000088372 Ensembl ENSMUSP00000092002 EMBL AAH81462.1 MGI 95589
ORF Names:	mCG_17237 EMBL EDL37096.1

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	183 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis By similarity. RuleBase RU000622
Sequence similarities	Belongs to the ferritin family. RuleBase RU000622 Contains 1 ferritin-like diiron domain. SAAS SAAS014034 RuleBase RU003668

Ontologies

Keywords
Biological process	Iron storage SAAS SAAS009040 RuleBase RU000622
Ligand	Iron Metal-binding SAAS SAAS009040 RuleBase RU000622
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cellular iron ion homeostasis Inferred from electronic annotation. Source: UniProtKB-KW iron ion transport Inferred from electronic annotation. Source: InterPro
Molecular_function	ferric iron binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9CPX4 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: ED39E8CCBABA590B	FASTA	183	20,772
	10 20 30 40 50 60 MTSQIRQNYS TEVEAAVNRL VNLHLRASYT YLSLGFFFDR DDVALEGVGH FFRELAEEKR 70 80 90 100 110 120 EGAERLLEFQ NDRGGRALFQ DVQKPSQDEW GKTQEAMEAA LAMEKNLNQA LLDLHALGSA 130 140 150 160 170 180 RADPHLCDFL ESHYLDKEVK LIKKMGNHLT NLRRVAGPQP AQTGAPQGSL GEYLFERLTL KHD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB27491.1 and NOD EMBL BAC40475.1. Tissue: Amnion EMBL BAE40576.1, Bone marrow EMBL BAE29596.1, Kidney EMBL BAB21959.1, Liver EMBL BAB27328.1, Thymus EMBL BAC40475.1 and Whole body EMBL BAB27491.1.
[2]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB27491.1 and NOD EMBL BAC40475.1. Tissue: Amnion EMBL BAE40576.1, Bone marrow EMBL BAE29596.1, Kidney EMBL BAB21959.1, Liver EMBL BAB27328.1, Thymus EMBL BAC40475.1 and Whole body EMBL BAB27491.1.
[3]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB27491.1 and NOD EMBL BAC40475.1. Tissue: Amnion EMBL BAE40576.1, Bone marrow EMBL BAE29596.1, Kidney EMBL BAB21959.1, Liver EMBL BAB27328.1, Thymus EMBL BAC40475.1 and Whole body EMBL BAB27491.1.
[4]	Adachi J., Aizawa K., Akahira S., Akimura T., Arai A., Aono H., Arakawa T., Bono H., Carninci P., Fukuda S., Fukunishi Y., Furuno M., Hanagaki T., Hara A., Hayatsu N., Hiramoto K., Hiraoka T., Hori F. , Imotani K., Ishii Y., Itoh M., Izawa M., Kasukawa T., Kato H., Kawai J., Kojima Y., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Nishi K., Nomura K., Numazaki R., Ohno M., Okazaki Y., Okido T., Owa C., Saito H., Saito R., Sakai C., Sakai K., Sano H., Sasaki D., Shibata K., Shibata Y., Shinagawa A., Shiraki T., Sogabe Y., Suzuki H., Tagami M., Tagawa A., Takahashi F., Tanaka T., Tejima Y., Toya T., Yamamura T., Yasunishi A., Yoshida K., Yoshino M., Muramatsu M., Hayashizaki Y. Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB27491.1. Tissue: Kidney EMBL BAB21959.1, Liver EMBL BAB27328.1 and Whole body EMBL BAB27491.1.
[5]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB27491.1 and NOD EMBL BAC40475.1. Tissue: Amnion EMBL BAE40576.1, Bone marrow EMBL BAE29596.1, Kidney EMBL BAB21959.1, Liver EMBL BAB27328.1, Thymus EMBL BAC40475.1 and Whole body EMBL BAB27491.1.
[6]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB27491.1 and NOD EMBL BAC40475.1. Tissue: Amnion EMBL BAE40576.1, Bone marrow EMBL BAE29596.1, Kidney EMBL BAB21959.1, Liver EMBL BAB27328.1, Thymus EMBL BAC40475.1 and Whole body EMBL BAB27491.1.
[7]	"A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome." Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D. Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL37096.1.
[8]	Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P., Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W., Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T., Hori F., Imotani K. , Ishii Y., Itoh M., Kagawa I., Kasukawa T., Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M., Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y., Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H., Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M., Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T., Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y. Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: NOD EMBL BAC40475.1. Tissue: Thymus EMBL BAC40475.1.
[9]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6 EMBL AAH81462.1, FVB/N EMBL AAH92259.1 and FVB/N-3 EMBL AAH85309.1. Tissue: Brain EMBL AAH81462.1, Colon EMBL AAI06147.1, Liver EMBL AAH92259.1 and Mammary tumor. MMTV-LTR/INT3 model. 5 month old mouse. Taken by biopsy. EMBL AAH85309.1.
[10]	Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y. Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE29596.1. Tissue: Bone marrow EMBL BAE29596.1.
[11]	Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y. Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE40576.1. Tissue: Amnion EMBL BAE40576.1 and Kidney EMBL BAE40685.1.
[12]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB27491.1 and NOD EMBL BAC40475.1. Tissue: Amnion EMBL BAE40576.1, Bone marrow EMBL BAE29596.1, Kidney EMBL BAB21959.1, Liver EMBL BAB27328.1, Thymus EMBL BAC40475.1 and Whole body EMBL BAB27491.1.
[13]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB27491.1 and NOD EMBL BAC40475.1. Tissue: Amnion EMBL BAE40576.1, Bone marrow EMBL BAE29596.1, Kidney EMBL BAB21959.1, Liver EMBL BAB27328.1, Thymus EMBL BAC40475.1 and Whole body EMBL BAB27491.1.
[14]	Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL37096.1.
[15]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000088372 Ensembl ENSMUSP00000092002.
[16]	Ensembl Submitted (JUN-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000088372 Ensembl ENSMUSP00000092002.
[17]	Ensembl Submitted (MAY-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000092002.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC151602 Genomic DNA. No translation available. CT009486 Genomic DNA. No translation available. BC081462 mRNA. Translation: AAH81462.1. BC083350 mRNA. Translation: AAH83350.1. BC085309 mRNA. Translation: AAH85309.1. BC092259 mRNA. Translation: AAH92259.1. BC106146 mRNA. Translation: AAI06147.1. AK002242 mRNA. Translation: BAB21959.1. AK002253 mRNA. Translation: BAB21967.1. AK011009 mRNA. Translation: BAB27328.1. AK011029 mRNA. Translation: BAB27345.1. AK011244 mRNA. Translation: BAB27491.1. AK088647 mRNA. Translation: BAC40475.1. AK150480 mRNA. Translation: BAE29596.1. AK151255 mRNA. Translation: BAE30244.1. AK152030 mRNA. Translation: BAE30889.1. AK152385 mRNA. Translation: BAE31173.1. AK152393 mRNA. Translation: BAE31181.1. AK152564 mRNA. Translation: BAE31317.1. AK152612 mRNA. Translation: BAE31357.1. AK159574 mRNA. Translation: BAE35195.1. AK168735 mRNA. Translation: BAE40576.1. AK168862 mRNA. Translation: BAE40681.1. AK168866 mRNA. Translation: BAE40685.1. AK169100 mRNA. Translation: BAE40883.1. AK169159 mRNA. Translation: BAE40938.1. CH466563 Genomic DNA. Translation: EDL37096.1. CH466563 Genomic DNA. Translation: EDL37097.1.
IPI	IPI00608020.
RefSeq	NP_034370.2. NM_010240.2. XP_003689256.2. XM_003689208.2. XP_003945736.1. XM_003945687.1. XP_003945737.1. XM_003945688.1.
UniGene	Mm.30357. Mm.348374. Mm.431913. Mm.486189.
3D structure databases
SMR	Q9CPX4. Positions 3-180.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9CPX4. 2 interactions.
MINT	MINT-217864.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000090860; ENSMUSP00000088372; ENSMUSG00000062382. ENSMUST00000094434; ENSMUSP00000092002; ENSMUSG00000050708.
GeneID	100862446. 14325.
KEGG	mmu:100862446. mmu:14325.
UCSC	uc009gvf.1. mouse.
Organism-specific databases
CTD	14325.
MGI	MGI:95589. Ftl1.
Phylogenomic databases
GeneTree	ENSGT00700000104338.
HOVERGEN	HBG000410.
InParanoid	Q9CPX4.
KO	K13625.
OMA	YLRASYT.
Gene expression databases
Genevestigator	Q9CPX4.
Family and domain databases
Gene3D	1.20.1260.10. 1 hit.
InterPro	IPR001519. Ferritin. IPR009040. Ferritin-like_diiron. IPR009078. Ferritin-like_SF. IPR012347. Ferritin-rel. IPR014034. Ferritin_CS. IPR008331. Ferritin_DPS_dom. [Graphical view]
PANTHER	PTHR11431. PTHR11431. 1 hit.
Pfam	PF00210. Ferritin. 1 hit. [Graphical view]
SUPFAM	SSF47240. Ferritin/RR_like. 1 hit.
PROSITE	PS00540. FERRITIN_1. 1 hit. PS00204. FERRITIN_2. 1 hit. PS50905. FERRITIN_LIKE. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	Ftl1. mouse.
NextBio	285769.
SOURCE	Search...

Entry information

Entry name

Q9CPX4_MOUSE

Accession

Primary (citable) accession number: Q9CPX4

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	May 29, 2013
This is version 107 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)