Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9CPX4

- Q9CPX4_MOUSE

UniProt

Q9CPX4 - Q9CPX4_MOUSE

Protein

Ferritin

Gene

Ftl1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.UniRule annotation

    GO - Molecular functioni

    1. ferric iron binding Source: InterPro

    GO - Biological processi

    1. cellular iron ion homeostasis Source: UniProtKB-KW
    2. iron ion transport Source: InterPro

    Keywords - Biological processi

    Iron storageUniRule annotationSAAS annotation

    Keywords - Ligandi

    Iron, Metal-bindingUniRule annotationSAAS annotation

    Enzyme and pathway databases

    ReactomeiREACT_205755. Iron uptake and transport.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    FerritinUniRule annotation
    Gene namesi
    Name:Ftl1Imported
    ORF Names:mCG_17237Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 7

    Organism-specific databases

    MGIiMGI:95589. Ftl1.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9CPX4.

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-217864.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ferritin family.UniRule annotation
    Contains 1 ferritin-like diiron domain.UniRule annotation
    Contains ferritin-like diiron domain.SAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00740000115277.
    HOVERGENiHBG000410.
    InParanoidiQ9CPX4.
    KOiK13625.
    OMAiMYLQASY.
    OrthoDBiEOG7DRJ49.
    TreeFamiTF313885.

    Family and domain databases

    Gene3Di1.20.1260.10. 1 hit.
    InterProiIPR001519. Ferritin.
    IPR009040. Ferritin-like_diiron.
    IPR009078. Ferritin-like_SF.
    IPR012347. Ferritin-rel.
    IPR014034. Ferritin_CS.
    IPR008331. Ferritin_DPS_dom.
    [Graphical view]
    PANTHERiPTHR11431. PTHR11431. 1 hit.
    PfamiPF00210. Ferritin. 1 hit.
    [Graphical view]
    SUPFAMiSSF47240. SSF47240. 1 hit.
    PROSITEiPS00540. FERRITIN_1. 1 hit.
    PS00204. FERRITIN_2. 1 hit.
    PS50905. FERRITIN_LIKE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9CPX4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTSQIRQNYS TEVEAAVNRL VNLHLRASYT YLSLGFFFDR DDVALEGVGH    50
    FFRELAEEKR EGAERLLEFQ NDRGGRALFQ DVQKPSQDEW GKTQEAMEAA 100
    LAMEKNLNQA LLDLHALGSA RADPHLCDFL ESHYLDKEVK LIKKMGNHLT 150
    NLRRVAGPQP AQTGAPQGSL GEYLFERLTL KHD 183
    Length:183
    Mass (Da):20,772
    Last modified:June 1, 2001 - v1
    Checksum:iED39E8CCBABA590B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC151602 Genomic DNA. No translation available.
    CT009486 Genomic DNA. No translation available.
    BC081462 mRNA. Translation: AAH81462.1.
    BC083350 mRNA. Translation: AAH83350.1.
    BC085309 mRNA. Translation: AAH85309.1.
    BC092259 mRNA. Translation: AAH92259.1.
    BC106146 mRNA. Translation: AAI06147.1.
    AK002242 mRNA. Translation: BAB21959.1.
    AK002253 mRNA. Translation: BAB21967.1.
    AK011009 mRNA. Translation: BAB27328.1.
    AK011029 mRNA. Translation: BAB27345.1.
    AK011244 mRNA. Translation: BAB27491.1.
    AK088647 mRNA. Translation: BAC40475.1.
    AK150480 mRNA. Translation: BAE29596.1.
    AK151255 mRNA. Translation: BAE30244.1.
    AK152030 mRNA. Translation: BAE30889.1.
    AK152385 mRNA. Translation: BAE31173.1.
    AK152393 mRNA. Translation: BAE31181.1.
    AK152564 mRNA. Translation: BAE31317.1.
    AK152612 mRNA. Translation: BAE31357.1.
    AK159574 mRNA. Translation: BAE35195.1.
    AK168735 mRNA. Translation: BAE40576.1.
    AK168862 mRNA. Translation: BAE40681.1.
    AK168866 mRNA. Translation: BAE40685.1.
    AK169100 mRNA. Translation: BAE40883.1.
    AK169159 mRNA. Translation: BAE40938.1.
    CH466563 Genomic DNA. Translation: EDL37096.1.
    CH466563 Genomic DNA. Translation: EDL37097.1.
    RefSeqiNP_034370.2. NM_010240.2.
    XP_003689256.2. XM_003689208.3.
    UniGeneiMm.30357.
    Mm.348374.
    Mm.431913.
    Mm.491102.

    Genome annotation databases

    EnsembliENSMUST00000090860; ENSMUSP00000088372; ENSMUSG00000062382.
    ENSMUST00000094434; ENSMUSP00000092002; ENSMUSG00000050708.
    GeneIDi100862446.
    14325.
    KEGGimmu:100862446.
    mmu:14325.
    UCSCiuc009gvf.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC151602 Genomic DNA. No translation available.
    CT009486 Genomic DNA. No translation available.
    BC081462 mRNA. Translation: AAH81462.1 .
    BC083350 mRNA. Translation: AAH83350.1 .
    BC085309 mRNA. Translation: AAH85309.1 .
    BC092259 mRNA. Translation: AAH92259.1 .
    BC106146 mRNA. Translation: AAI06147.1 .
    AK002242 mRNA. Translation: BAB21959.1 .
    AK002253 mRNA. Translation: BAB21967.1 .
    AK011009 mRNA. Translation: BAB27328.1 .
    AK011029 mRNA. Translation: BAB27345.1 .
    AK011244 mRNA. Translation: BAB27491.1 .
    AK088647 mRNA. Translation: BAC40475.1 .
    AK150480 mRNA. Translation: BAE29596.1 .
    AK151255 mRNA. Translation: BAE30244.1 .
    AK152030 mRNA. Translation: BAE30889.1 .
    AK152385 mRNA. Translation: BAE31173.1 .
    AK152393 mRNA. Translation: BAE31181.1 .
    AK152564 mRNA. Translation: BAE31317.1 .
    AK152612 mRNA. Translation: BAE31357.1 .
    AK159574 mRNA. Translation: BAE35195.1 .
    AK168735 mRNA. Translation: BAE40576.1 .
    AK168862 mRNA. Translation: BAE40681.1 .
    AK168866 mRNA. Translation: BAE40685.1 .
    AK169100 mRNA. Translation: BAE40883.1 .
    AK169159 mRNA. Translation: BAE40938.1 .
    CH466563 Genomic DNA. Translation: EDL37096.1 .
    CH466563 Genomic DNA. Translation: EDL37097.1 .
    RefSeqi NP_034370.2. NM_010240.2.
    XP_003689256.2. XM_003689208.3.
    UniGenei Mm.30357.
    Mm.348374.
    Mm.431913.
    Mm.491102.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-217864.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000090860 ; ENSMUSP00000088372 ; ENSMUSG00000062382 .
    ENSMUST00000094434 ; ENSMUSP00000092002 ; ENSMUSG00000050708 .
    GeneIDi 100862446.
    14325.
    KEGGi mmu:100862446.
    mmu:14325.
    UCSCi uc009gvf.1. mouse.

    Organism-specific databases

    CTDi 14325.
    MGIi MGI:95589. Ftl1.

    Phylogenomic databases

    GeneTreei ENSGT00740000115277.
    HOVERGENi HBG000410.
    InParanoidi Q9CPX4.
    KOi K13625.
    OMAi MYLQASY.
    OrthoDBi EOG7DRJ49.
    TreeFami TF313885.

    Enzyme and pathway databases

    Reactomei REACT_205755. Iron uptake and transport.

    Miscellaneous databases

    ChiTaRSi Ftl1. mouse.
    NextBioi 285769.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q9CPX4.

    Family and domain databases

    Gene3Di 1.20.1260.10. 1 hit.
    InterProi IPR001519. Ferritin.
    IPR009040. Ferritin-like_diiron.
    IPR009078. Ferritin-like_SF.
    IPR012347. Ferritin-rel.
    IPR014034. Ferritin_CS.
    IPR008331. Ferritin_DPS_dom.
    [Graphical view ]
    PANTHERi PTHR11431. PTHR11431. 1 hit.
    Pfami PF00210. Ferritin. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47240. SSF47240. 1 hit.
    PROSITEi PS00540. FERRITIN_1. 1 hit.
    PS00204. FERRITIN_2. 1 hit.
    PS50905. FERRITIN_LIKE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and NODImported.
      Tissue: AmnionImported, Bone marrowImported, KidneyImported, LiverImported, ThymusImported and Whole bodyImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and NODImported.
      Tissue: AmnionImported, Bone marrowImported, KidneyImported, LiverImported, ThymusImported and Whole bodyImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and NODImported.
      Tissue: AmnionImported, Bone marrowImported, KidneyImported, LiverImported, ThymusImported and Whole bodyImported.
    4. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: KidneyImported, LiverImported and Whole bodyImported.
    5. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and NODImported.
      Tissue: AmnionImported, Bone marrowImported, KidneyImported, LiverImported, ThymusImported and Whole bodyImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and NODImported.
      Tissue: AmnionImported, Bone marrowImported, KidneyImported, LiverImported, ThymusImported and Whole bodyImported.
    7. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: NODImported.
      Tissue: ThymusImported.
    9. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6Imported, FVB/NImported and FVB/N-3Imported.
      Tissue: BrainImported, ColonImported, LiverImported and Mammary tumor. MMTV-LTR/INT3 model. 5 month old mouse. Taken by biopsy.Imported.
    10. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Bone marrowImported.
    11. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: AmnionImported and KidneyImported.
    12. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and NODImported.
      Tissue: AmnionImported, Bone marrowImported, KidneyImported, LiverImported, ThymusImported and Whole bodyImported.
    13. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and NODImported.
      Tissue: AmnionImported, Bone marrowImported, KidneyImported, LiverImported, ThymusImported and Whole bodyImported.
    14. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    15. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    16. Ensembl
      Submitted (JUN-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.
    17. Ensembl
      Submitted (MAY-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ9CPX4_MOUSE
    AccessioniPrimary (citable) accession number: Q9CPX4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2001
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 117 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3