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Protein

Ferritin

Gene

Ftl1-ps1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Iron storageUniRule annotationSAAS annotation

Keywords - Ligandi

Iron, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-MMU-432722. Golgi Associated Vesicle Biogenesis.
R-MMU-6798695. Neutrophil degranulation.
R-MMU-917937. Iron uptake and transport.

Names & Taxonomyi

Protein namesi
Recommended name:
FerritinUniRule annotation
Gene namesi
Name:Ftl1-ps1Imported
Synonyms:Ftl1Imported
ORF Names:mCG_17237Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componentsi: Chromosome 13, Chromosome 7

Organism-specific databases

MGIiMGI:95589. Ftl1.
MGI:3779109. Ftl1-ps1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

TopDownProteomicsiQ9CPX4.

Expressioni

Gene expression databases

BgeeiENSMUSG00000050708.

Interactioni

Protein-protein interaction databases

MINTiMINT-217864.
STRINGi10090.ENSMUSP00000092002.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 156Ferritin-like diironInterPro annotationAdd BLAST150

Sequence similaritiesi

Belongs to the ferritin family.UniRule annotation
Contains 1 ferritin-like diiron domain.UniRule annotation

Phylogenomic databases

eggNOGiKOG2332. Eukaryota.
COG1528. LUCA.
GeneTreeiENSGT00760000119129.
HOVERGENiHBG000410.
KOiK13625.
OMAiAQDEWGR.
OrthoDBiEOG091G0J20.
TreeFamiTF313885.

Family and domain databases

Gene3Di1.20.1260.10. 1 hit.
InterProiIPR001519. Ferritin.
IPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR014034. Ferritin_CS.
IPR008331. Ferritin_DPS_dom.
[Graphical view]
PANTHERiPTHR11431. PTHR11431. 1 hit.
PfamiPF00210. Ferritin. 1 hit.
[Graphical view]
SUPFAMiSSF47240. SSF47240. 1 hit.
PROSITEiPS00540. FERRITIN_1. 1 hit.
PS00204. FERRITIN_2. 1 hit.
PS50905. FERRITIN_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9CPX4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSQIRQNYS TEVEAAVNRL VNLHLRASYT YLSLGFFFDR DDVALEGVGH
60 70 80 90 100
FFRELAEEKR EGAERLLEFQ NDRGGRALFQ DVQKPSQDEW GKTQEAMEAA
110 120 130 140 150
LAMEKNLNQA LLDLHALGSA RADPHLCDFL ESHYLDKEVK LIKKMGNHLT
160 170 180
NLRRVAGPQP AQTGAPQGSL GEYLFERLTL KHD
Length:183
Mass (Da):20,772
Last modified:June 1, 2001 - v1
Checksum:iED39E8CCBABA590B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC151602 Genomic DNA. No translation available.
CT009486 Genomic DNA. No translation available.
BC081462 mRNA. Translation: AAH81462.1.
BC083350 mRNA. Translation: AAH83350.1.
BC085309 mRNA. Translation: AAH85309.1.
BC092259 mRNA. Translation: AAH92259.1.
BC106146 mRNA. Translation: AAI06147.1.
AK002242 mRNA. Translation: BAB21959.1.
AK002253 mRNA. Translation: BAB21967.1.
AK011009 mRNA. Translation: BAB27328.1.
AK011029 mRNA. Translation: BAB27345.1.
AK011244 mRNA. Translation: BAB27491.1.
AK088647 mRNA. Translation: BAC40475.1.
AK150480 mRNA. Translation: BAE29596.1.
AK151255 mRNA. Translation: BAE30244.1.
AK152030 mRNA. Translation: BAE30889.1.
AK152385 mRNA. Translation: BAE31173.1.
AK152393 mRNA. Translation: BAE31181.1.
AK152564 mRNA. Translation: BAE31317.1.
AK152612 mRNA. Translation: BAE31357.1.
AK159574 mRNA. Translation: BAE35195.1.
AK168735 mRNA. Translation: BAE40576.1.
AK168862 mRNA. Translation: BAE40681.1.
AK168866 mRNA. Translation: BAE40685.1.
AK169100 mRNA. Translation: BAE40883.1.
AK169159 mRNA. Translation: BAE40938.1.
CH466563 Genomic DNA. Translation: EDL37096.1.
CH466563 Genomic DNA. Translation: EDL37097.1.
RefSeqiNP_034370.2. NM_010240.2.
XP_003689256.2. XM_003689208.3.
UniGeneiMm.30357.
Mm.348374.
Mm.431913.
Mm.491102.

Genome annotation databases

EnsembliENSMUST00000090860; ENSMUSP00000088372; ENSMUSG00000062382.
ENSMUST00000094434; ENSMUSP00000092002; ENSMUSG00000050708.
GeneIDi100862446.
14325.
KEGGimmu:100862446.
mmu:14325.
UCSCiuc009gvf.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC151602 Genomic DNA. No translation available.
CT009486 Genomic DNA. No translation available.
BC081462 mRNA. Translation: AAH81462.1.
BC083350 mRNA. Translation: AAH83350.1.
BC085309 mRNA. Translation: AAH85309.1.
BC092259 mRNA. Translation: AAH92259.1.
BC106146 mRNA. Translation: AAI06147.1.
AK002242 mRNA. Translation: BAB21959.1.
AK002253 mRNA. Translation: BAB21967.1.
AK011009 mRNA. Translation: BAB27328.1.
AK011029 mRNA. Translation: BAB27345.1.
AK011244 mRNA. Translation: BAB27491.1.
AK088647 mRNA. Translation: BAC40475.1.
AK150480 mRNA. Translation: BAE29596.1.
AK151255 mRNA. Translation: BAE30244.1.
AK152030 mRNA. Translation: BAE30889.1.
AK152385 mRNA. Translation: BAE31173.1.
AK152393 mRNA. Translation: BAE31181.1.
AK152564 mRNA. Translation: BAE31317.1.
AK152612 mRNA. Translation: BAE31357.1.
AK159574 mRNA. Translation: BAE35195.1.
AK168735 mRNA. Translation: BAE40576.1.
AK168862 mRNA. Translation: BAE40681.1.
AK168866 mRNA. Translation: BAE40685.1.
AK169100 mRNA. Translation: BAE40883.1.
AK169159 mRNA. Translation: BAE40938.1.
CH466563 Genomic DNA. Translation: EDL37096.1.
CH466563 Genomic DNA. Translation: EDL37097.1.
RefSeqiNP_034370.2. NM_010240.2.
XP_003689256.2. XM_003689208.3.
UniGeneiMm.30357.
Mm.348374.
Mm.431913.
Mm.491102.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-217864.
STRINGi10090.ENSMUSP00000092002.

Proteomic databases

TopDownProteomicsiQ9CPX4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000090860; ENSMUSP00000088372; ENSMUSG00000062382.
ENSMUST00000094434; ENSMUSP00000092002; ENSMUSG00000050708.
GeneIDi100862446.
14325.
KEGGimmu:100862446.
mmu:14325.
UCSCiuc009gvf.1. mouse.

Organism-specific databases

CTDi14325.
MGIiMGI:95589. Ftl1.
MGI:3779109. Ftl1-ps1.

Phylogenomic databases

eggNOGiKOG2332. Eukaryota.
COG1528. LUCA.
GeneTreeiENSGT00760000119129.
HOVERGENiHBG000410.
KOiK13625.
OMAiAQDEWGR.
OrthoDBiEOG091G0J20.
TreeFamiTF313885.

Enzyme and pathway databases

ReactomeiR-MMU-432722. Golgi Associated Vesicle Biogenesis.
R-MMU-6798695. Neutrophil degranulation.
R-MMU-917937. Iron uptake and transport.

Miscellaneous databases

ChiTaRSiFtl1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000050708.

Family and domain databases

Gene3Di1.20.1260.10. 1 hit.
InterProiIPR001519. Ferritin.
IPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR014034. Ferritin_CS.
IPR008331. Ferritin_DPS_dom.
[Graphical view]
PANTHERiPTHR11431. PTHR11431. 1 hit.
PfamiPF00210. Ferritin. 1 hit.
[Graphical view]
SUPFAMiSSF47240. SSF47240. 1 hit.
PROSITEiPS00540. FERRITIN_1. 1 hit.
PS00204. FERRITIN_2. 1 hit.
PS50905. FERRITIN_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9CPX4_MOUSE
AccessioniPrimary (citable) accession number: Q9CPX4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: November 30, 2016
This is version 140 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.