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Q9CPX4

- Q9CPX4_MOUSE

UniProt

Q9CPX4 - Q9CPX4_MOUSE

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Protein

Ferritin

Gene
Ftl1, mCG_17237
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation By similarity.UniRule annotation

GO - Molecular functioni

  1. ferric iron binding Source: InterPro

GO - Biological processi

  1. cellular iron ion homeostasis Source: UniProtKB-KW
  2. iron ion transport Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Iron storageUniRule annotationSAAS annotations

Keywords - Ligandi

Iron, Metal-bindingUniRule annotationSAAS annotations

Enzyme and pathway databases

ReactomeiREACT_205755. Iron uptake and transport.

Names & Taxonomyi

Protein namesi
Recommended name:
FerritinUniRule annotation
Gene namesi
Name:Ftl1Imported
ORF Names:mCG_17237Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 13, UP000000589: Chromosome 7

Organism-specific databases

MGIiMGI:95589. Ftl1.

Expressioni

Gene expression databases

GenevestigatoriQ9CPX4.

Interactioni

Protein-protein interaction databases

MINTiMINT-217864.

Family & Domainsi

Sequence similaritiesi

Belongs to the ferritin family.UniRule annotation
Contains 1 ferritin-like diiron domain.UniRule annotation
Contains ferritin-like diiron domain.SAAS annotations

Phylogenomic databases

GeneTreeiENSGT00740000115277.
HOVERGENiHBG000410.
InParanoidiQ9CPX4.
KOiK13625.
OMAiMYLQASY.
OrthoDBiEOG7DRJ49.
TreeFamiTF313885.

Family and domain databases

Gene3Di1.20.1260.10. 1 hit.
InterProiIPR001519. Ferritin.
IPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR014034. Ferritin_CS.
IPR008331. Ferritin_DPS_dom.
[Graphical view]
PANTHERiPTHR11431. PTHR11431. 1 hit.
PfamiPF00210. Ferritin. 1 hit.
[Graphical view]
SUPFAMiSSF47240. SSF47240. 1 hit.
PROSITEiPS00540. FERRITIN_1. 1 hit.
PS00204. FERRITIN_2. 1 hit.
PS50905. FERRITIN_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9CPX4-1 [UniParc]FASTAAdd to Basket

« Hide

MTSQIRQNYS TEVEAAVNRL VNLHLRASYT YLSLGFFFDR DDVALEGVGH    50
FFRELAEEKR EGAERLLEFQ NDRGGRALFQ DVQKPSQDEW GKTQEAMEAA 100
LAMEKNLNQA LLDLHALGSA RADPHLCDFL ESHYLDKEVK LIKKMGNHLT 150
NLRRVAGPQP AQTGAPQGSL GEYLFERLTL KHD 183
Length:183
Mass (Da):20,772
Last modified:June 1, 2001 - v1
Checksum:iED39E8CCBABA590B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC151602 Genomic DNA. No translation available.
CT009486 Genomic DNA. No translation available.
BC081462 mRNA. Translation: AAH81462.1.
BC083350 mRNA. Translation: AAH83350.1.
BC085309 mRNA. Translation: AAH85309.1.
BC092259 mRNA. Translation: AAH92259.1.
BC106146 mRNA. Translation: AAI06147.1.
AK002242 mRNA. Translation: BAB21959.1.
AK002253 mRNA. Translation: BAB21967.1.
AK011009 mRNA. Translation: BAB27328.1.
AK011029 mRNA. Translation: BAB27345.1.
AK011244 mRNA. Translation: BAB27491.1.
AK088647 mRNA. Translation: BAC40475.1.
AK150480 mRNA. Translation: BAE29596.1.
AK151255 mRNA. Translation: BAE30244.1.
AK152030 mRNA. Translation: BAE30889.1.
AK152385 mRNA. Translation: BAE31173.1.
AK152393 mRNA. Translation: BAE31181.1.
AK152564 mRNA. Translation: BAE31317.1.
AK152612 mRNA. Translation: BAE31357.1.
AK159574 mRNA. Translation: BAE35195.1.
AK168735 mRNA. Translation: BAE40576.1.
AK168862 mRNA. Translation: BAE40681.1.
AK168866 mRNA. Translation: BAE40685.1.
AK169100 mRNA. Translation: BAE40883.1.
AK169159 mRNA. Translation: BAE40938.1.
CH466563 Genomic DNA. Translation: EDL37096.1.
CH466563 Genomic DNA. Translation: EDL37097.1.
RefSeqiNP_034370.2. NM_010240.2.
XP_003689256.2. XM_003689208.3.
UniGeneiMm.30357.
Mm.348374.
Mm.431913.
Mm.491102.

Genome annotation databases

EnsembliENSMUST00000090860; ENSMUSP00000088372; ENSMUSG00000062382.
ENSMUST00000094434; ENSMUSP00000092002; ENSMUSG00000050708.
GeneIDi100862446.
14325.
KEGGimmu:100862446.
mmu:14325.
UCSCiuc009gvf.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC151602 Genomic DNA. No translation available.
CT009486 Genomic DNA. No translation available.
BC081462 mRNA. Translation: AAH81462.1 .
BC083350 mRNA. Translation: AAH83350.1 .
BC085309 mRNA. Translation: AAH85309.1 .
BC092259 mRNA. Translation: AAH92259.1 .
BC106146 mRNA. Translation: AAI06147.1 .
AK002242 mRNA. Translation: BAB21959.1 .
AK002253 mRNA. Translation: BAB21967.1 .
AK011009 mRNA. Translation: BAB27328.1 .
AK011029 mRNA. Translation: BAB27345.1 .
AK011244 mRNA. Translation: BAB27491.1 .
AK088647 mRNA. Translation: BAC40475.1 .
AK150480 mRNA. Translation: BAE29596.1 .
AK151255 mRNA. Translation: BAE30244.1 .
AK152030 mRNA. Translation: BAE30889.1 .
AK152385 mRNA. Translation: BAE31173.1 .
AK152393 mRNA. Translation: BAE31181.1 .
AK152564 mRNA. Translation: BAE31317.1 .
AK152612 mRNA. Translation: BAE31357.1 .
AK159574 mRNA. Translation: BAE35195.1 .
AK168735 mRNA. Translation: BAE40576.1 .
AK168862 mRNA. Translation: BAE40681.1 .
AK168866 mRNA. Translation: BAE40685.1 .
AK169100 mRNA. Translation: BAE40883.1 .
AK169159 mRNA. Translation: BAE40938.1 .
CH466563 Genomic DNA. Translation: EDL37096.1 .
CH466563 Genomic DNA. Translation: EDL37097.1 .
RefSeqi NP_034370.2. NM_010240.2.
XP_003689256.2. XM_003689208.3.
UniGenei Mm.30357.
Mm.348374.
Mm.431913.
Mm.491102.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

MINTi MINT-217864.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000090860 ; ENSMUSP00000088372 ; ENSMUSG00000062382 .
ENSMUST00000094434 ; ENSMUSP00000092002 ; ENSMUSG00000050708 .
GeneIDi 100862446.
14325.
KEGGi mmu:100862446.
mmu:14325.
UCSCi uc009gvf.1. mouse.

Organism-specific databases

CTDi 14325.
MGIi MGI:95589. Ftl1.

Phylogenomic databases

GeneTreei ENSGT00740000115277.
HOVERGENi HBG000410.
InParanoidi Q9CPX4.
KOi K13625.
OMAi MYLQASY.
OrthoDBi EOG7DRJ49.
TreeFami TF313885.

Enzyme and pathway databases

Reactomei REACT_205755. Iron uptake and transport.

Miscellaneous databases

ChiTaRSi Ftl1. mouse.
NextBioi 285769.
SOURCEi Search...

Gene expression databases

Genevestigatori Q9CPX4.

Family and domain databases

Gene3Di 1.20.1260.10. 1 hit.
InterProi IPR001519. Ferritin.
IPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR014034. Ferritin_CS.
IPR008331. Ferritin_DPS_dom.
[Graphical view ]
PANTHERi PTHR11431. PTHR11431. 1 hit.
Pfami PF00210. Ferritin. 1 hit.
[Graphical view ]
SUPFAMi SSF47240. SSF47240. 1 hit.
PROSITEi PS00540. FERRITIN_1. 1 hit.
PS00204. FERRITIN_2. 1 hit.
PS50905. FERRITIN_LIKE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported and NODImported.
    Tissue: AmnionImported, Bone marrowImported, KidneyImported, LiverImported, ThymusImported and Whole bodyImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported and NODImported.
    Tissue: AmnionImported, Bone marrowImported, KidneyImported, LiverImported, ThymusImported and Whole bodyImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported and NODImported.
    Tissue: AmnionImported, Bone marrowImported, KidneyImported, LiverImported, ThymusImported and Whole bodyImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: KidneyImported, LiverImported and Whole bodyImported.
  5. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported and NODImported.
    Tissue: AmnionImported, Bone marrowImported, KidneyImported, LiverImported, ThymusImported and Whole bodyImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported and NODImported.
    Tissue: AmnionImported, Bone marrowImported, KidneyImported, LiverImported, ThymusImported and Whole bodyImported.
  7. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
    Tissue: ThymusImported.
  9. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6Imported, FVB/NImported and FVB/N-3Imported.
    Tissue: BrainImported, ColonImported, LiverImported and Mammary tumor. MMTV-LTR/INT3 model. 5 month old mouse. Taken by biopsy.Imported.
  10. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Bone marrowImported.
  11. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: AmnionImported and KidneyImported.
  12. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported and NODImported.
    Tissue: AmnionImported, Bone marrowImported, KidneyImported, LiverImported, ThymusImported and Whole bodyImported.
  13. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported and NODImported.
    Tissue: AmnionImported, Bone marrowImported, KidneyImported, LiverImported, ThymusImported and Whole bodyImported.
  14. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  15. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  16. Ensembl
    Submitted (JUN-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.
  17. Ensembl
    Submitted (MAY-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ9CPX4_MOUSE
AccessioniPrimary (citable) accession number: Q9CPX4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: September 3, 2014
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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