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Protein

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial

Gene

Ndufb2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.By similarity

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chain, Transport

Enzyme and pathway databases

ReactomeiR-MMU-611105. Respiratory electron transport.
R-MMU-6799198. Complex I biogenesis.

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial
Alternative name(s):
Complex I-AGGG
Short name:
CI-AGGG
NADH-ubiquinone oxidoreductase AGGG subunit
Gene namesi
Name:Ndufb2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:1915448. Ndufb2.

Subcellular locationi

  • Mitochondrion inner membrane By similarity; Peripheral membrane protein By similarity; Matrix side By similarity

GO - Cellular componenti

  • mitochondrial respiratory chain complex I Source: MGI
  • mitochondrion Source: MGI

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 33MitochondrionBy similarityAdd BLAST33
ChainiPRO_000002004334 – 105NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrialAdd BLAST72

Proteomic databases

MaxQBiQ9CPU2.
PaxDbiQ9CPU2.
PeptideAtlasiQ9CPU2.
PRIDEiQ9CPU2.
TopDownProteomicsiQ9CPU2.

PTM databases

PhosphoSitePlusiQ9CPU2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000002416.
GenevisibleiQ9CPU2. MM.

Interactioni

Subunit structurei

Complex I is composed of 45 different subunits.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000114095.

Structurei

3D structure databases

SMRiQ9CPU2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I NDUFB2 subunit family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiENOG410J0BK. Eukaryota.
ENOG41128HF. LUCA.
GeneTreeiENSGT00390000004044.
HOGENOMiHOG000252974.
HOVERGENiHBG006499.
InParanoidiQ9CPU2.
KOiK03958.
OMAiFSATMWF.
OrthoDBiEOG091G0YSW.
PhylomeDBiQ9CPU2.
TreeFamiTF316619.

Family and domain databases

InterProiView protein in InterPro
IPR026627. NDUFB2.
PANTHERiPTHR15223. PTHR15223. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9CPU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSALTRLVPF GRVGGRLLRG CRARAAGDSG VRHAGGGVHI QPRYREFPQL
60 70 80 90 100
TRSQVIQGEF LSSLMWFWIL WRFWHDSDAV LGHFSYPDPS QWTDEELGIP

PDDED
Length:105
Mass (Da):11,967
Last modified:June 1, 2001 - v1
Checksum:iF5D5019BFA33E510
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK007495 mRNA. Translation: BAB25068.1.
AK010642 mRNA. Translation: BAB27084.1.
AK019008 mRNA. Translation: BAB31508.1.
AK028334 mRNA. Translation: BAC25887.1.
BC013510 mRNA. Translation: AAH13510.1.
CCDSiCCDS20025.1.
RefSeqiNP_080888.1. NM_026612.3.
XP_006506592.1. XM_006506529.3.
UniGeneiMm.29415.

Genome annotation databases

EnsembliENSMUST00000119379; ENSMUSP00000114095; ENSMUSG00000002416.
ENSMUST00000135671; ENSMUSP00000118918; ENSMUSG00000002416.
GeneIDi68198.
KEGGimmu:68198.
UCSCiuc009bmc.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiNDUB2_MOUSE
AccessioniPrimary (citable) accession number: Q9CPU2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: June 1, 2001
Last modified: August 30, 2017
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families