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Q9CPR5

- RM15_MOUSE

UniProt

Q9CPR5 - RM15_MOUSE

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Protein

39S ribosomal protein L15, mitochondrial

Gene
Mrpl15
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. structural constituent of ribosome Source: MGI

GO - Biological processi

  1. mitochondrial genome maintenance Source: MGI
  2. translation Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L15, mitochondrial
Short name:
L15mt
Short name:
MRP-L15
Gene namesi
Name:Mrpl15
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 1

Organism-specific databases

MGIiMGI:1351639. Mrpl15.

Subcellular locationi

GO - Cellular componenti

  1. mitochondrial large ribosomal subunit Source: MGI
  2. mitochondrion Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 2020Mitochondrion By similarityAdd
BLAST
Chaini21 – 29527539S ribosomal protein L15, mitochondrialPRO_0000257839Add
BLAST

Proteomic databases

MaxQBiQ9CPR5.
PaxDbiQ9CPR5.
PRIDEiQ9CPR5.

PTM databases

PhosphoSiteiQ9CPR5.

Expressioni

Gene expression databases

ArrayExpressiQ9CPR5.
BgeeiQ9CPR5.
CleanExiMM_MRPL15.
GenevestigatoriQ9CPR5.

Interactioni

Protein-protein interaction databases

BioGridi205202. 6 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ9CPR5.
SMRiQ9CPR5. Positions 21-176.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi33 – 6331Arg-richAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG0200.
GeneTreeiENSGT00390000009040.
HOVERGENiHBG088294.
InParanoidiQ9CPR5.
KOiK02876.
OMAiFRNIFAK.
OrthoDBiEOG7NKKNG.
PhylomeDBiQ9CPR5.
TreeFamiTF105918.

Family and domain databases

InterProiIPR005749. Ribosomal_L15_bac-type.
IPR021131. Ribosomal_L18e/L15P.
[Graphical view]
PANTHERiPTHR12934. PTHR12934. 1 hit.
PfamiPF00828. Ribosomal_L18e. 1 hit.
[Graphical view]
SUPFAMiSSF52080. SSF52080. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9CPR5-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MAGTARGCGT SLDLLRSLPR VSLANLKPSP NSRKRERRPR DRRRGRKCGR    50
GHKGERQRGT RPRLGFEGGQ TPFYIRIPKY GFNEGHSFRH QYQPLSLRRL 100
QYLIDLGRVD PTQPIDLTQL VNGRGVTIQP LKRDYGVQLV EEGADTFQAK 150
INIEVQLASE LAIAAIEKNG GVVTTAFYDP RSLEILCKPI PFFLRGQPIP 200
KRMLPPESLV PYYTDAKNRG YLADPAKFPE ARLELAMKFG YVLPDITKDE 250
LFRMLSARKD PRQIFFGLAP GWVVNMADKK ILKPTDENLL KYYSS 295
Length:295
Mass (Da):33,542
Last modified:June 1, 2001 - v1
Checksum:i2CAA781E82E4670C
GO
Isoform 2 (identifier: Q9CPR5-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     184-204: EILCKPIPFFLRGQPIPKRML → GHLMHSSDFHGFSARYSIHIK
     205-295: Missing.

Show »
Length:204
Mass (Da):23,018
Checksum:iE9EBEF2A98811C16
GO

Sequence cautioni

The sequence BAB27054.1 differs from that shown. Reason: Erroneous initiation.

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei184 – 20421EILCK…PKRML → GHLMHSSDFHGFSARYSIHI K in isoform 2. VSP_021370Add
BLAST
Alternative sequencei205 – 29591Missing in isoform 2. VSP_021371Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti1 – 11M → L in BAB27054. 1 Publication
Sequence conflicti13 – 131D → G in BAB27054. 1 Publication
Sequence conflicti36 – 361E → G in BAB27054. 1 Publication
Sequence conflicti119 – 1191Q → K in BAE29929. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK003367 mRNA. Translation: BAB22741.1.
AK010474 mRNA. Translation: BAB26967.1.
AK010604 mRNA. Translation: BAB27054.1. Different initiation.
AK017804 mRNA. Translation: BAB30943.1.
AK017824 mRNA. Translation: BAB30958.1.
AK019175 mRNA. Translation: BAB31589.1.
AK019249 mRNA. Translation: BAB31626.1.
AK150880 mRNA. Translation: BAE29929.1.
AK160660 mRNA. Translation: BAE35948.1.
BC021304 mRNA. Translation: AAH21304.1.
BC027233 mRNA. Translation: AAH27233.1.
CCDSiCCDS35504.1. [Q9CPR5-2]
CCDS48211.1. [Q9CPR5-1]
RefSeqiNP_001171129.1. NM_001177658.1. [Q9CPR5-1]
NP_079576.1. NM_025300.4. [Q9CPR5-2]
UniGeneiMm.182927.

Genome annotation databases

EnsembliENSMUST00000130201; ENSMUSP00000114649; ENSMUSG00000033845. [Q9CPR5-2]
ENSMUST00000156816; ENSMUSP00000115512; ENSMUSG00000033845. [Q9CPR5-1]
GeneIDi27395.
KEGGimmu:27395.
UCSCiuc007afd.3. mouse. [Q9CPR5-2]
uc007aff.3. mouse. [Q9CPR5-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK003367 mRNA. Translation: BAB22741.1 .
AK010474 mRNA. Translation: BAB26967.1 .
AK010604 mRNA. Translation: BAB27054.1 . Different initiation.
AK017804 mRNA. Translation: BAB30943.1 .
AK017824 mRNA. Translation: BAB30958.1 .
AK019175 mRNA. Translation: BAB31589.1 .
AK019249 mRNA. Translation: BAB31626.1 .
AK150880 mRNA. Translation: BAE29929.1 .
AK160660 mRNA. Translation: BAE35948.1 .
BC021304 mRNA. Translation: AAH21304.1 .
BC027233 mRNA. Translation: AAH27233.1 .
CCDSi CCDS35504.1. [Q9CPR5-2 ]
CCDS48211.1. [Q9CPR5-1 ]
RefSeqi NP_001171129.1. NM_001177658.1. [Q9CPR5-1 ]
NP_079576.1. NM_025300.4. [Q9CPR5-2 ]
UniGenei Mm.182927.

3D structure databases

ProteinModelPortali Q9CPR5.
SMRi Q9CPR5. Positions 21-176.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 205202. 6 interactions.

PTM databases

PhosphoSitei Q9CPR5.

Proteomic databases

MaxQBi Q9CPR5.
PaxDbi Q9CPR5.
PRIDEi Q9CPR5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000130201 ; ENSMUSP00000114649 ; ENSMUSG00000033845 . [Q9CPR5-2 ]
ENSMUST00000156816 ; ENSMUSP00000115512 ; ENSMUSG00000033845 . [Q9CPR5-1 ]
GeneIDi 27395.
KEGGi mmu:27395.
UCSCi uc007afd.3. mouse. [Q9CPR5-2 ]
uc007aff.3. mouse. [Q9CPR5-1 ]

Organism-specific databases

CTDi 29088.
MGIi MGI:1351639. Mrpl15.

Phylogenomic databases

eggNOGi COG0200.
GeneTreei ENSGT00390000009040.
HOVERGENi HBG088294.
InParanoidi Q9CPR5.
KOi K02876.
OMAi FRNIFAK.
OrthoDBi EOG7NKKNG.
PhylomeDBi Q9CPR5.
TreeFami TF105918.

Miscellaneous databases

NextBioi 305370.
PROi Q9CPR5.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q9CPR5.
Bgeei Q9CPR5.
CleanExi MM_MRPL15.
Genevestigatori Q9CPR5.

Family and domain databases

InterProi IPR005749. Ribosomal_L15_bac-type.
IPR021131. Ribosomal_L18e/L15P.
[Graphical view ]
PANTHERi PTHR12934. PTHR12934. 1 hit.
Pfami PF00828. Ribosomal_L18e. 1 hit.
[Graphical view ]
SUPFAMi SSF52080. SSF52080. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Strain: C57BL/6J.
    Tissue: Bone marrow and Embryo.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Strain: FVB/N.
    Tissue: Mammary tumor.

Entry informationi

Entry nameiRM15_MOUSE
AccessioniPrimary (citable) accession number: Q9CPR5
Secondary accession number(s): Q3UBN5, Q9CPP5, Q9CRH4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: June 1, 2001
Last modified: July 9, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi