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Q9CPR5 (RM15_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
39S ribosomal protein L15, mitochondrial
Short name=L15mt
Short name=MRP-L15
Gene names
Name:Mrpl15
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length295 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Mitochondrion.

Sequence similarities

Belongs to the ribosomal protein L15P family.

Sequence caution

The sequence BAB27054.1 differs from that shown. Reason: Erroneous initiation.

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q9CPR5-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q9CPR5-2)

The sequence of this isoform differs from the canonical sequence as follows:
     184-204: EILCKPIPFFLRGQPIPKRML → GHLMHSSDFHGFSARYSIHIK
     205-295: Missing.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 2020Mitochondrion By similarity
Chain21 – 29527539S ribosomal protein L15, mitochondrial
PRO_0000257839

Regions

Compositional bias33 – 6331Arg-rich

Natural variations

Alternative sequence184 – 20421EILCK…PKRML → GHLMHSSDFHGFSARYSIHI K in isoform 2.
VSP_021370
Alternative sequence205 – 29591Missing in isoform 2.
VSP_021371

Experimental info

Sequence conflict11M → L in BAB27054. Ref.1
Sequence conflict131D → G in BAB27054. Ref.1
Sequence conflict361E → G in BAB27054. Ref.1
Sequence conflict1191Q → K in BAE29929. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 2CAA781E82E4670C

FASTA29533,542
        10         20         30         40         50         60 
MAGTARGCGT SLDLLRSLPR VSLANLKPSP NSRKRERRPR DRRRGRKCGR GHKGERQRGT 

        70         80         90        100        110        120 
RPRLGFEGGQ TPFYIRIPKY GFNEGHSFRH QYQPLSLRRL QYLIDLGRVD PTQPIDLTQL 

       130        140        150        160        170        180 
VNGRGVTIQP LKRDYGVQLV EEGADTFQAK INIEVQLASE LAIAAIEKNG GVVTTAFYDP 

       190        200        210        220        230        240 
RSLEILCKPI PFFLRGQPIP KRMLPPESLV PYYTDAKNRG YLADPAKFPE ARLELAMKFG 

       250        260        270        280        290 
YVLPDITKDE LFRMLSARKD PRQIFFGLAP GWVVNMADKK ILKPTDENLL KYYSS

« Hide

Isoform 2 [UniParc].

Checksum: E9EBEF2A98811C16
Show »

FASTA20423,018

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
Strain: C57BL/6J.
Tissue: Bone marrow and Embryo.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
Strain: FVB/N.
Tissue: Mammary tumor.
[3]"Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria."
Mootha V.K., Bunkenborg J., Olsen J.V., Hjerrild M., Wisniewski J.R., Stahl E., Bolouri M.S., Ray H.N., Sihag S., Kamal M., Patterson N., Lander E.S., Mann M.
Cell 115:629-640(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], SUBCELLULAR LOCATION.
Strain: C57BL/6J.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AK003367 mRNA. Translation: BAB22741.1.
AK010474 mRNA. Translation: BAB26967.1.
AK010604 mRNA. Translation: BAB27054.1. Different initiation.
AK017804 mRNA. Translation: BAB30943.1.
AK017824 mRNA. Translation: BAB30958.1.
AK019175 mRNA. Translation: BAB31589.1.
AK019249 mRNA. Translation: BAB31626.1.
AK150880 mRNA. Translation: BAE29929.1.
AK160660 mRNA. Translation: BAE35948.1.
BC021304 mRNA. Translation: AAH21304.1.
BC027233 mRNA. Translation: AAH27233.1.
IPIIPI00131732.
IPI00798614.
RefSeqNP_001171129.1. NM_001177658.1.
NP_079576.1. NM_025300.4.
UniGeneMm.182927.

3D structure databases

ProteinModelPortalQ9CPR5.
SMRQ9CPR5. Positions 23-82.
ModBaseSearch...

PTM databases

PhosphoSiteQ9CPR5.

Proteomic databases

PaxDbQ9CPR5.
PRIDEQ9CPR5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000130201; ENSMUSP00000114649; ENSMUSG00000033845.
ENSMUST00000156816; ENSMUSP00000115512; ENSMUSG00000033845.
GeneID27395.
KEGGmmu:27395.
UCSCuc007afd.3. mouse.
uc007aff.3. mouse.

Organism-specific databases

CTD29088.
MGIMGI:1351639. Mrpl15.

Phylogenomic databases

eggNOGCOG0200.
GeneTreeENSGT00390000009040.
HOVERGENHBG088294.
InParanoidQ9CPR5.
KOK02876.
OMAVHKFTAS.
OrthoDBEOG441QC5.

Gene expression databases

ArrayExpressQ9CPR5.
BgeeQ9CPR5.
CleanExMM_MRPL15.
GenevestigatorQ9CPR5.
GermOnlineENSMUSG00000033845. Mus musculus.

Family and domain databases

InterProIPR005749. Ribosomal_L15_bac-type.
IPR021131. Ribosomal_L18e/L15P.
[Graphical view]
PANTHERPTHR12934. PTHR12934. 1 hit.
PfamPF00828. Ribosomal_L18e. 1 hit.
[Graphical view]
SUPFAMSSF52080. Ribosomal_L18e/L15. 1 hit.
PROSITEPS00475. RIBOSOMAL_L15. False negative.
[Graphical view]
ProtoNetSearch...

Other

NextBio305370.
SOURCESearch...

Entry information

Entry nameRM15_MOUSE
AccessionPrimary (citable) accession number: Q9CPR5
Secondary accession number(s): Q3UBN5, Q9CPP5, Q9CRH4
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: June 1, 2001
Last modified: May 29, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

Ribosomal proteins

Ribosomal proteins families and list of entries

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents