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Protein
Submitted name:

Growth hormone a1

Gene

Prl

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHormoneUniRule annotation

Enzyme and pathway databases

ReactomeiR-MMU-1170546. Prolactin receptor signaling.
R-MMU-982772. Growth hormone receptor signaling.

Names & Taxonomyi

Protein namesi
Submitted name:
Growth hormone a1Imported
Submitted name:
ProlactinImported
Submitted name:
Prolactin, isoform CRA_aImported
Gene namesi
Name:PrlImported
Synonyms:Gha1Imported
ORF Names:mCG_15525Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:97762. Prl.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 31Sequence analysisAdd BLAST31
ChainiPRO_501097729932 – 228Sequence analysisAdd BLAST197

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000021342.

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the somatotropin/prolactin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410II74. Eukaryota.
ENOG410XU1S. LUCA.
GeneTreeiENSGT00730000110805.
HOGENOMiHOG000264241.
HOVERGENiHBG104895.
OMAiDSHKIDN.
OrthoDBiEOG091G0O08.
TreeFamiTF332592.

Family and domain databases

InterProiView protein in InterPro
IPR009079. 4_helix_cytokine-like_core.
IPR001400. Somatotropin/Prolactin.
IPR018116. Somatotropin_CS.
PANTHERiPTHR11417. PTHR11417. 1 hit.
PfamiView protein in Pfam
PF00103. Hormone_1. 1 hit.
PRINTSiPR00836. SOMATOTROPIN.
SUPFAMiSSF47266. SSF47266. 1 hit.
PROSITEiView protein in PROSITE
PS00338. SOMATOTROPIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9CPQ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTMNSQGSAQ KAGTLLLLLI SNLLFCQNVQ PLPICSAGDC QTSLRELFDR
60 70 80 90 100
VVILSHYIHT LYTDMFIEFD KQYVQDREFM VKVINDCPTS SLATPEDKEQ
110 120 130 140 150
ALKVPPEVLL NLILSLVQSS SDPLFQLITG VGGIQEAPEY ILSRAKEIEE
160 170 180 190 200
QNKQLLEGVE KIISQAYPEA KGNGIYFVWS QLPSLQGVDE ESKILSLRNT
210 220
IRCLRRDSHK VDNFLKVLRC QIAHQNNC
Length:228
Mass (Da):25,729
Last modified:June 1, 2001 - v1
Checksum:iAFCADF003728CD77
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591843 Genomic DNA. No translation available.
BC061141 mRNA. Translation: AAH61141.1.
AK077493 mRNA. Translation: BAC36829.1.
AK133736 mRNA. Translation: BAE21811.1.
AK133752 mRNA. Translation: BAE21822.1.
AK161557 mRNA. Translation: BAE36462.1.
AK161565 mRNA. Translation: BAE36467.1.
AK161619 mRNA. Translation: BAE36497.1.
LM644166 mRNA. Translation: CDW51413.1.
CH466561 Genomic DNA. Translation: EDL32452.1.
PIRiA43789. LCMS.
RefSeqiNP_035294.2. NM_011164.2.
UniGeneiMm.1270.

Genome annotation databases

EnsembliENSMUST00000110369; ENSMUSP00000105998; ENSMUSG00000021342.
GeneIDi19109.
UCSCiuc007pxb.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ9CPQ2_MOUSE
AccessioniPrimary (citable) accession number: Q9CPQ2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: September 27, 2017
This is version 137 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported