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Protein
Submitted name:

Prolactin

Gene

Prl

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHormoneUniRule annotation

Enzyme and pathway databases

ReactomeiR-MMU-1170546. Prolactin receptor signaling.
R-MMU-982772. Growth hormone receptor signaling.

Names & Taxonomyi

Protein namesi
Submitted name:
ProlactinImported
Gene namesi
Name:PrlImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:97762. Prl.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_501121248729 – 225Sequence analysisAdd BLAST197

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000021342.

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the somatotropin/prolactin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410II74. Eukaryota.
ENOG410XU1S. LUCA.
GeneTreeiENSGT00730000110805.
HOVERGENiHBG104895.

Family and domain databases

InterProiView protein in InterPro
IPR009079. 4_helix_cytokine-like_core.
IPR001400. Somatotropin/Prolactin.
IPR018116. Somatotropin_CS.
PANTHERiPTHR11417. PTHR11417. 1 hit.
PfamiView protein in Pfam
PF00103. Hormone_1. 1 hit.
PRINTSiPR00836. SOMATOTROPIN.
SUPFAMiSSF47266. SSF47266. 1 hit.
PROSITEiView protein in PROSITE
PS00338. SOMATOTROPIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9CPQ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSQGSAQKG TLLLLLISNL LFCQNVQPLP ICSAGDCQTS LRELFDRVVI
60 70 80 90 100
LSHYIHTLYT DMFIEFDKQY VQDREFMVKV INDCPTSSLA TPEDKEQALK
110 120 130 140 150
VPPEVLLNLI LSLVQSSSDP LFQLITGVGG IQEAPEYILS RAKEIEEQNK
160 170 180 190 200
QLLEGVEKII SQAYPEAKGN GIYFVWSQLP SLQGVDEESK ILSLRNTIRC
210 220
LRRDSHKVDN FLKVLRCQIA HQNNC
Length:225
Mass (Da):25,425
Last modified:June 1, 2003 - v2
Checksum:i027245C6EEA3E3DE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591843 Genomic DNA. No translation available.
AK017520 mRNA. Translation: BAB30786.2.
AK017584 mRNA. Translation: BAB30821.2.
UniGeneiMm.1270.

Genome annotation databases

EnsembliENSMUST00000018061; ENSMUSP00000018061; ENSMUSG00000021342.

Similar proteinsi

Entry informationi

Entry nameiQ9CPQ0_MOUSE
AccessioniPrimary (citable) accession number: Q9CPQ0
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2003
Last modified: November 22, 2017
This is version 130 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported