Q9CPI5 (MENF_PASMU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Menaquinone-specific isochorismate synthase
EC=5.4.4.2

Alternative name(s):
Isochorismate mutase

Gene names

Name:	menF
Ordered Locus Names:	PM0053

Organism

Pasteurella multocida (strain Pm70) [Complete proteome] [HAMAP]

Taxonomic identifier

272843 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Pasteurella

Protein attributes

Sequence length	431 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Chorismate = isochorismate.
Pathway	Cofactor biosynthesis; menaquinone biosynthesis; menaquinone-2 from chorismate: step 1/8.
Sequence similarities	Belongs to the isochorismate synthase family.

Ontologies

Keywords
Biological process	Menaquinone biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	menaquinone biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	isochorismate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 431	431	Menaquinone-specific isochorismate synthase		PRO_0000154149

Sequences

	Sequence		Length	Mass (Da)
	Q9CPI5 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: DE03AB3C43AE740F	FASTA	431	48,727
	10 20 30 40 50 60 MDNLQSIKAQ FIAQINAYQP EKDRDIVVFQ CNTETTFSLL AWLKAQQYYP QFYLHGRDGA 70 80 90 100 110 120 TKWASIGQVR QFSDVSAAAH FIQEQQLALL GGLQFYGDAL FVLPRLLLQQ RQDGMTITLF 130 140 150 160 170 180 IDGKQFEQDK LVALACLSTF EKQTALQTVK QEISLISQKA DQAEWCRWVE QGLQKIKQGE 190 200 210 220 230 240 LSKIVLANER CFKTAAPLAA TDLLAESEKY NLGCYHFMLA ESEQRAFIGS SPELLYRRHG 250 260 270 280 290 300 LQLKTEALAG TAFMGEDEQQ NQQQSDWLLH DKKNEYENQL VVDGICQNLQ PFVQQITIEK 310 320 330 340 350 360 VELKKLRKVQ HLRRRISAQL KAGCGDKDIL LAMHPTAAVA GLPQLEAKQA LRKLENFDRT 370 380 390 400 410 420 WYAGTLGVMG PAYADFCVTI RSAFIEQAEN DSQLCVFAGA GIVEGSIPLL EWREIERKAM 430 GLVSLLQQNQ L

References

[1]	"Complete genomic sequence of Pasteurella multocida Pm70." May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V. Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001) [PubMed: 11248100] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Pm70.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE004439 Genomic DNA. Translation: AAK02137.1.
RefSeq	NP_244990.1. NC_002663.1.
3D structure databases
ProteinModelPortal	Q9CPI5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1243400.
GenomeReviews	Gene locus PM0053 in contig AE004439_GR.
KEGG	pmu:PM0053.
NMPDR	fig|272843.1.peg.53.
PATRIC	22869238. VBIPasMul88067_0054.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG405459.
OMA	WYAGTLG.
ProtClustDB	CLSK869946.
Enzyme and pathway databases
BioCyc	PMUL272843:PM0053-MONOMER.
Family and domain databases
InterPro	IPR005801. ADC_synthase. IPR015890. Chorismate-bd_C. IPR004561. IsoChor_synthase. [Graphical view]
Gene3D	G3DSA:3.60.120.10. TRPE_1_chor_bd. 1 hit.
KO	K02552.
PANTHER	PTHR11236:SF3. Isochor_synth. 1 hit.
Pfam	PF00425. Chorismate_bind. 1 hit. [Graphical view]
SUPFAM	SSF56322. TRPE_1_chor_bd. 1 hit.
TIGRFAMs	TIGR00543. Isochor_syn. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MENF_PASMU

Accession

Primary (citable) accession number: Q9CPI5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 5, 2002
Last sequence update:	June 1, 2001
Last modified:	January 25, 2012
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program