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Q9CPB1 (Q9CPB1_PASMU) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase RuleBase RU004136
EC=6.3.2.10 RuleBase RU004136
Gene names
Name:murF EMBL AAK02222.1
Ordered Locus Names:PM0138
OrganismPasteurella multocida (strain Pm70) [Complete proteome] [HAMAP]
Taxonomic identifier272843 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Pasteurella

Protein attributes

Sequence length460 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein By similarity. RuleBase RU004136

Catalytic activity

ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine. RuleBase RU004136

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. RuleBase RU004136

Subcellular location

Cytoplasm By similarity RuleBase RU004136.

Sequence similarities

Belongs to the MurCDEF family. RuleBase RU003630

Sequences

Sequence LengthMass (Da)Tools
Q9CPB1 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 174676BB004E7B1E

FASTA46050,353
        10         20         30         40         50         60 
MLKLTTKQLA TILQAELVGE ANVVVENIST DTRQRVASSL FFALKGEHFD AHNYLDKAVA 

        70         80         90        100        110        120 
QGANALVVER ADTQISVPQL IVKDTRIALG ELAKWVKQQV NPRTLAMTGS SGKTTVKEMT 

       130        140        150        160        170        180 
ASILQSAVGV EQVLFTQGNF NNDIGVPLTL LRLTEQHQFA VIELGANHQG EIAYTTGLVQ 

       190        200        210        220        230        240 
PNVALVNNVA AAHLEGFGSL EGVATAKGEI YRGLQPDGVA IINKEHDYRS TWAQDIGAHR 

       250        260        270        280        290        300 
VQYFAYQDNT ADFYADNVIF HEAGSTFDLC TPQGKTTIHL PYLGEHNVKN ALAASALAMN 

       310        320        330        340        350        360 
VGATLAQIKQ GLEVRTQVKG RLYPVQPCDN LLLLDDTYNA NVDSLQSAIR VLQKYDAFRI 

       370        380        390        400        410        420 
LVVGDMAELG ENSQICHQQV AECAKAAKLE RVYSFGSESA VISQACLGKH FTDKALLCRE 

       430        440        450        460 
LTQLLSEKLK ENQKIVLLAK GSRRMQMEDV INTLRENFVC

« Hide

References

[1]"Complete genomic sequence of Pasteurella multocida Pm70."
May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V.
Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001) [PubMed: 11248100] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Pm70.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE004439 Genomic DNA. Translation: AAK02222.1.
RefSeqNP_245075.1. NC_002663.1.

3D structure databases

HSSPHSSP built from PDB template 1GG4 based on UniProtKB P11880.
ProteinModelPortalQ9CPB1.
SMRQ9CPB1. Positions 1-455.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1243485.
GenomeReviewsGene locus PM0138 in contig AE004439_GR.
KEGGpmu:PM0138.
NMPDRfig|272843.1.peg.138.
PATRIC22869420. VBIPasMul88067_0143.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG617121.
OMAYAVIEMG.
ProtClustDBCLSK869981.

Enzyme and pathway databases

BioCycPMUL272843:PM0138-MONOMER.

Family and domain databases

InterProIPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
IPR000713. Mur_ligase_N.
IPR005863. UDP-N-AcMur-pentapeptide_synth.
[Graphical view]
Gene3DG3DSA:3.90.190.20. Mur_ligase_C. 1 hit.
G3DSA:3.40.1190.10. Mur_ligase_cen. 1 hit.
KOK01929.
PANTHERPTHR23135:SF3. MurF. 1 hit.
PfamPF01225. Mur_ligase. 1 hit.
PF02875. Mur_ligase_C. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view]
SUPFAMSSF53244. Mur_ligase_C. 1 hit.
SSF53623. Mur_ligase_cen. 1 hit.
TIGRFAMsTIGR01143. MurF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ9CPB1_PASMU
AccessionPrimary (citable) accession number: Q9CPB1
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: December 14, 2011
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info