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Q9CNL2 (G6PI_PASMU) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:PM0416
OrganismPasteurella multocida (strain Pm70) [Complete proteome] [HAMAP]
Taxonomic identifier272843 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaePasteurella

Protein attributes

Sequence length549 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 549549Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180700

Sites

Active site3551Proton donor By similarity
Active site3871 By similarity
Active site5151 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9CNL2 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: E6E4856927B93283

FASTA54961,438
        10         20         30         40         50         60 
MKNINPTTTN AWKALQQHHK TQSAVTIQQL FAQEKDRFTD YSLSFNNEVL VDFSKNNVTK 

        70         80         90        100        110        120 
ETLGLLRQLA QECALSEAVD AMFSGAKINK TEDRAVLHTA LRNRSNSPVL VDGKDVMPEV 

       130        140        150        160        170        180 
NAVLAKMKDF CHRVISGEWK GYTGKAITDV VNIGIGGSDL GPYMVTEALR PYKNHLNLHF 

       190        200        210        220        230        240 
VSNVDGTHIA ETLKKVNPET TLFLVASKTF TTQETMTNAH SARNWFLATA KDESHVAKHF 

       250        260        270        280        290        300 
AALSTNSKAV AEFGIDTNNM FEFWDWVGGR YSLWSAIGLS IALSIGFEHF EALLAGAHEM 

       310        320        330        340        350        360 
DKHFRTAPIE QNIPTTLALI GLWNTNFLGA QTEAILPYDQ YLHRFAAYFQ QGNMESNGKY 

       370        380        390        400        410        420 
VDRNGEVIDN YQTGPIIWGE PGTNGQHAFY QLIHQGTTLI PCDFIAPAQT HNPLADHHEK 

       430        440        450        460        470        480 
LLSNFFAQTE ALAFGKTKEE VEAEFVKAGK SLDEVKEVVP FKVFTGNKPT NSILVQKITP 

       490        500        510        520        530        540 
FTLGALIAMY EHKIFVQGVM FNIYSFDQWG VELGKQLANR ILPELANRET ITTHDSSTNG 


LINQYKQWR 

« Hide

References

[1]"Complete genomic sequence of Pasteurella multocida Pm70."
May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V.
Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Pm70.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE004439 Genomic DNA. Translation: AAK02500.1.
RefSeqNP_245353.1. NC_002663.1.

3D structure databases

ProteinModelPortalQ9CNL2.
SMRQ9CNL2. Positions 7-549.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272843.PM0416.

Proteomic databases

PRIDEQ9CNL2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK02500; AAK02500; PM0416.
GeneID1243763.
KEGGpmu:PM0416.
PATRIC22870006. VBIPasMul88067_0428.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261371.
KOK01810.
OMANCHFVAN.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycPMUL272843:GC8W-427-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_PASMU
AccessionPrimary (citable) accession number: Q9CNL2
Entry history
Integrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: June 1, 2001
Last modified: June 11, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways