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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Pasteurella multocida (strain Pm70)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei355Proton donorBy similarity1
Active sitei387By similarity1
Active sitei515By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciPMUL272843:G1FZ8-436-MONOMER
UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:PM0416
OrganismiPasteurella multocida (strain Pm70)
Taxonomic identifieri272843 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaePasteurella
Proteomesi
  • UP000000809 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001807001 – 549Glucose-6-phosphate isomeraseAdd BLAST549

Proteomic databases

PRIDEiQ9CNL2

Interactioni

Protein-protein interaction databases

STRINGi272843.PM0416

Structurei

3D structure databases

ProteinModelPortaliQ9CNL2
SMRiQ9CNL2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.Curated

Phylogenomic databases

eggNOGiENOG4107QP8 Bacteria
COG0166 LUCA
HOGENOMiHOG000261371
KOiK01810
OMAiTNSQHAF

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.101 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q9CNL2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNINPTTTN AWKALQQHHK TQSAVTIQQL FAQEKDRFTD YSLSFNNEVL
60 70 80 90 100
VDFSKNNVTK ETLGLLRQLA QECALSEAVD AMFSGAKINK TEDRAVLHTA
110 120 130 140 150
LRNRSNSPVL VDGKDVMPEV NAVLAKMKDF CHRVISGEWK GYTGKAITDV
160 170 180 190 200
VNIGIGGSDL GPYMVTEALR PYKNHLNLHF VSNVDGTHIA ETLKKVNPET
210 220 230 240 250
TLFLVASKTF TTQETMTNAH SARNWFLATA KDESHVAKHF AALSTNSKAV
260 270 280 290 300
AEFGIDTNNM FEFWDWVGGR YSLWSAIGLS IALSIGFEHF EALLAGAHEM
310 320 330 340 350
DKHFRTAPIE QNIPTTLALI GLWNTNFLGA QTEAILPYDQ YLHRFAAYFQ
360 370 380 390 400
QGNMESNGKY VDRNGEVIDN YQTGPIIWGE PGTNGQHAFY QLIHQGTTLI
410 420 430 440 450
PCDFIAPAQT HNPLADHHEK LLSNFFAQTE ALAFGKTKEE VEAEFVKAGK
460 470 480 490 500
SLDEVKEVVP FKVFTGNKPT NSILVQKITP FTLGALIAMY EHKIFVQGVM
510 520 530 540
FNIYSFDQWG VELGKQLANR ILPELANRET ITTHDSSTNG LINQYKQWR
Length:549
Mass (Da):61,438
Last modified:June 1, 2001 - v1
Checksum:iE6E4856927B93283
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004439 Genomic DNA Translation: AAK02500.1
RefSeqiWP_005726133.1, NC_002663.1

Genome annotation databases

EnsemblBacteriaiAAK02500; AAK02500; PM0416
KEGGipmu:PM0416
PATRICifig|272843.6.peg.428

Similar proteinsi

Entry informationi

Entry nameiG6PI_PASMU
AccessioniPrimary (citable) accession number: Q9CNL2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: June 1, 2001
Last modified: February 28, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome