Reviewed, UniProtKB/Swiss-Prot Q9CN08 (BIOD1_PASMU)

Names and origin

Protein names

Recommended name:
    Probable dethiobiotin synthetase 1
      Short name=Dethiobiotin synthase 1
      Short name=DTB synthetase 1
      Short name=DTBS 1
    EC=6.3.3.3

Gene names

Name:	bioD1
Ordered Locus Names:	PM0641

Organism

Pasteurella multocida [Complete proteome] [HAMAP]

Taxonomic identifier

747 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Pasteurella

Protein attributes

Sequence length	244 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin. HAMAP MF_00336
Cofactor	Magnesium By similarity.
Pathway	Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2. HAMAP MF_00336
Sequence similarities	Belongs to the dethiobiotin synthetase family.

Ontologies

Keywords
Biological process	Biotin biosynthesis
Ligand	ATP-binding Magnesium Nucleotide-binding
Molecular function	Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	biotin biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP dethiobiotin synthase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 244	244	Probable dethiobiotin synthetase 1 HAMAP MF_00336		PRO_0000187980
Regions
	Nucleotide binding	8 – 16	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9CN08-1 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: B7E06C1A7C41DDFA	FASTA	244	27,581
	10 20 30 40 50 60 MSSFFLTGTD TNVGKTVASR AIIQALQNQG IQIVGYKPVA FSREECVYTD MENQQAAESD 70 80 90 100 110 120 YDSQNNSDVL TLMKSTHEKV SYQEINSYTF RHSLPVFSVQ GKHIRIEKMD ADLARLNQKY 130 140 150 160 170 180 QSVLVEGSYG WLTPINKTYC FADWAKSHQM PVVLVVGIKE GCLNHALLTV ESIQQKGLPL 190 200 210 220 230 240 LGWIANRINP CLGHYAEIID LLSEKIDAPL LGQIPYLHKP EEQDLARYIH NLDRLTYMET VLAD

References

[1]	"Complete genomic sequence of Pasteurella multocida Pm70." May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V. Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001) [PubMed: 11248100] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Pm70.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE004439 Genomic DNA. Translation: AAK02725.1.
RefSeq	NP_245578.1.
3D structure databases
HSSP	HSSP built from PDB template 1DAI based on UniProtKB P13000.
ModBase	Search...
Genome annotation databases
GeneID	1243988.
GenomeReviews	Gene locus PM0641 in contig AE004439_GR.
KEGG	pmu:PM0641.
NMPDR	fig|272843.1.peg.641.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q9CN08.
OMA	ETPEGMR.
Enzyme and pathway databases
BRENDA	6.3.3.3. 258935.
Family and domain databases
HAMAP	MF_00336. [Tree]
InterPro	IPR004472. BioD_synth. [Graphical view]
PIRSF	PIRSF006755. DTB_synth. 1 hit.
TIGRFAMs	TIGR00347. bioD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

BIOD1_PASMU

Accession

Primary (citable) accession number: Q9CN08

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 19, 2002
Last sequence update:	June 1, 2001
Last modified:	November 3, 2009
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)