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Q9CMY2

- FNR_PASMU

UniProt

Q9CMY2 - FNR_PASMU

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Protein

Anaerobic regulatory protein

Gene

fnr

Organism
Pasteurella multocida (strain Pm70)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

It is involved in the activation of genes necessary for anaerobic respiration.

Cofactori

[4Fe-4S] clusterBy similarityNote: Binds 1 [4Fe-4S] cluster per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi39 – 391Iron-sulfur (4Fe-4S)Sequence Analysis
Metal bindingi42 – 421Iron-sulfur (4Fe-4S)Sequence Analysis
Metal bindingi48 – 481Iron-sulfur (4Fe-4S)Sequence Analysis
Metal bindingi141 – 1411Iron-sulfur (4Fe-4S)Sequence Analysis

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi216 – 23520H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
  2. DNA binding Source: UniProtKB-KW
  3. metal ion binding Source: UniProtKB-KW
  4. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator, Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

4Fe-4S, DNA-binding, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciPMUL272843:GC8W-690-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Anaerobic regulatory protein
Gene namesi
Name:fnr
Ordered Locus Names:PM0668
OrganismiPasteurella multocida (strain Pm70)
Taxonomic identifieri272843 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaePasteurella
ProteomesiUP000000809: Chromosome

Subcellular locationi

Cytoplasm Curated

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 273273Anaerobic regulatory proteinPRO_0000100178Add
BLAST

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi272843.PM0668.

Structurei

3D structure databases

ProteinModelPortaliQ9CMY2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini183 – 25674HTH crp-typePROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni39 – 4810Essential for the oxygen-regulated activityBy similarity
Regioni159 – 17820DimerizationSequence AnalysisAdd
BLAST

Sequence similaritiesi

Contains 1 cyclic nucleotide-binding domain.PROSITE-ProRule annotation
Contains 1 HTH crp-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0664.
HOGENOMiHOG000186461.
KOiK01420.
OMAiFSANQFR.
OrthoDBiEOG6RVFWF.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProiIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
IPR001808. Tscrpt_reg_HTH_Crp.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00027. cNMP_binding. 1 hit.
PF00325. Crp. 1 hit.
[Graphical view]
PRINTSiPR00034. HTHCRP.
SMARTiSM00100. cNMP. 1 hit.
SM00419. HTH_CRP. 1 hit.
[Graphical view]
SUPFAMiSSF51206. SSF51206. 1 hit.
PROSITEiPS50042. CNMP_BINDING_3. 1 hit.
PS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9CMY2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MILFEIDQFY IIFVVLIKVL FMDTKIGRKV QSGGCAIHCQ DCSISQLCIP
60 70 80 90 100
FTLNEQELDQ LDNIIERKKP IQKSQVLFKA GDPLNSLYAI RSGTIKTYTI
110 120 130 140 150
SETGEEQITS FQLPGDLVGF DAIMNMQHPS FAQALETSMV CEIPFDILDD
160 170 180 190 200
LSGKMPKLRQ QIMRLMSNEI KNDQEMILLL SKMNAEERLA AFIYNLSRRY
210 220 230 240 250
SARGFSAREF RLTMTRGDIG NYLGLTVETI SRLLGRLQKM GILSVQGKYI
260 270
TINDMVALIE LSGTTKTNIK MGI
Length:273
Mass (Da):30,887
Last modified:June 1, 2001 - v1
Checksum:i9BF91D046DD35182
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004439 Genomic DNA. Translation: AAK02752.1.
RefSeqiNP_245605.1. NC_002663.1.
WP_010906782.1. NC_002663.1.

Genome annotation databases

EnsemblBacteriaiAAK02752; AAK02752; PM0668.
GeneIDi1244015.
KEGGipmu:PM0668.
PATRICi22870522. VBIPasMul88067_0676.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004439 Genomic DNA. Translation: AAK02752.1 .
RefSeqi NP_245605.1. NC_002663.1.
WP_010906782.1. NC_002663.1.

3D structure databases

ProteinModelPortali Q9CMY2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272843.PM0668.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK02752 ; AAK02752 ; PM0668 .
GeneIDi 1244015.
KEGGi pmu:PM0668.
PATRICi 22870522. VBIPasMul88067_0676.

Phylogenomic databases

eggNOGi COG0664.
HOGENOMi HOG000186461.
KOi K01420.
OMAi FSANQFR.
OrthoDBi EOG6RVFWF.

Enzyme and pathway databases

BioCyci PMUL272843:GC8W-690-MONOMER.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProi IPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
IPR001808. Tscrpt_reg_HTH_Crp.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00027. cNMP_binding. 1 hit.
PF00325. Crp. 1 hit.
[Graphical view ]
PRINTSi PR00034. HTHCRP.
SMARTi SM00100. cNMP. 1 hit.
SM00419. HTH_CRP. 1 hit.
[Graphical view ]
SUPFAMi SSF51206. SSF51206. 1 hit.
PROSITEi PS50042. CNMP_BINDING_3. 1 hit.
PS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Pm70.

Entry informationi

Entry nameiFNR_PASMU
AccessioniPrimary (citable) accession number: Q9CMY2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2002
Last sequence update: June 1, 2001
Last modified: November 26, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3