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Q9CMX5 (NAGK_PASMU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-acetyl-D-glucosamine kinase

EC=2.7.1.59
Alternative name(s):
GlcNAc kinase
Gene names
Name:nagK
Ordered Locus Names:PM0675
OrganismPasteurella multocida (strain Pm70) [Complete proteome] [HAMAP]
Taxonomic identifier272843 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaePasteurella

Protein attributes

Sequence length304 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P By similarity. HAMAP-Rule MF_01271

Catalytic activity

ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate. HAMAP-Rule MF_01271

Pathway

Cell wall biogenesis; peptidoglycan recycling. HAMAP-Rule MF_01271

Sequence similarities

Belongs to the ROK (NagC/XylR) family. NagK subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 304304N-acetyl-D-glucosamine kinase HAMAP-Rule MF_01271
PRO_0000270109

Regions

Nucleotide binding4 – 118ATP Potential
Nucleotide binding133 – 1408ATP Potential

Sites

Metal binding1571Zinc By similarity
Metal binding1781Zinc By similarity
Metal binding1801Zinc By similarity
Metal binding1851Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9CMX5 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 9E6A87AF91ABF786

FASTA30433,039
        10         20         30         40         50         60 
MRYGFDIGGT KIELAVFNDQ LEKQYSERVE TPKESYEEWL NTIVRLVHKA DEMFQCQGTV 

        70         80         90        100        110        120 
GLGIPGFVNP ATGIAEIVNI RAADHKPIIQ DLETRLGREV RAENDANCFA LSEAWDEENA 

       130        140        150        160        170        180 
QYPSVLGLIL GTGFGGGLIF NGKVHSGQTG MAGEVGHTQL NYHALRLLGG DNAPIYDCGC 

       190        200        210        220        230        240 
GNRACLDTYL SGRGFEMLYR DMQGEALSAQ AIIQRFYAGD QSAVKFVELF IELCAISIGN 

       250        260        270        280        290        300 
LITVLDPHVI VLGGGLSNFD YLYEALPKAL PARLLRSANV PLIKKAKYGD SGGVRGAAAL 


FLSK 

« Hide

References

[1]"Complete genomic sequence of Pasteurella multocida Pm70."
May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V.
Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Pm70.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE004439 Genomic DNA. Translation: AAK02759.1.
RefSeqNP_245612.1. NC_002663.1.

3D structure databases

ProteinModelPortalQ9CMX5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272843.PM0675.

Proteomic databases

PRIDEQ9CMX5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK02759; AAK02759; PM0675.
GeneID1244022.
KEGGpmu:PM0675.
PATRIC22870538. VBIPasMul88067_0684.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1940.
HOGENOMHOG000150087.
KOK00884.
OMAEHVDRFM.
OrthoDBEOG61P6P0.
ProtClustDBPRK13310.

Enzyme and pathway databases

BioCycPMUL272843:GC8W-697-MONOMER.
UniPathwayUPA00544.

Family and domain databases

HAMAPMF_01271. GlcNAc_kinase.
InterProIPR023505. N-acetyl-D-glucosamine_kinase.
IPR000600. ROK.
[Graphical view]
PfamPF00480. ROK. 1 hit.
[Graphical view]
PROSITEPS01125. ROK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNAGK_PASMU
AccessionPrimary (citable) accession number: Q9CMX5
Entry history
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: June 1, 2001
Last modified: April 16, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways