Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

N-acetyl-D-glucosamine kinase

Gene

nagK

Organism
Pasteurella multocida (strain Pm70)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.UniRule annotation

Catalytic activityi

ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate.UniRule annotation

Pathway: peptidoglycan recycling

This protein is involved in the pathway peptidoglycan recycling, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan recycling and in Cell wall biogenesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi157 – 1571ZincUniRule annotation
Metal bindingi178 – 1781ZincUniRule annotation
Metal bindingi180 – 1801ZincUniRule annotation
Metal bindingi185 – 1851ZincUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi4 – 118ATPUniRule annotation
Nucleotide bindingi133 – 1408ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Carbohydrate metabolism

Keywords - Ligandi

ATP-binding, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

BioCyciPMUL272843:GC8W-697-MONOMER.
UniPathwayiUPA00544.

Names & Taxonomyi

Protein namesi
Recommended name:
N-acetyl-D-glucosamine kinaseUniRule annotation (EC:2.7.1.59UniRule annotation)
Alternative name(s):
GlcNAc kinaseUniRule annotation
Gene namesi
Name:nagKUniRule annotation
Ordered Locus Names:PM0675
OrganismiPasteurella multocida (strain Pm70)
Taxonomic identifieri272843 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaePasteurella
ProteomesiUP000000809 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 304304N-acetyl-D-glucosamine kinasePRO_0000270109Add
BLAST

Proteomic databases

PRIDEiQ9CMX5.

Interactioni

Protein-protein interaction databases

STRINGi272843.PM0675.

Structurei

3D structure databases

ProteinModelPortaliQ9CMX5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ROK (NagC/XylR) family. NagK subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG1940.
HOGENOMiHOG000150087.
KOiK00884.
OMAiWIGNDAD.
OrthoDBiEOG61P6P0.

Family and domain databases

HAMAPiMF_01271. GlcNAc_kinase.
InterProiIPR023505. N-acetyl-D-glucosamine_kinase.
IPR000600. ROK.
[Graphical view]
PfamiPF00480. ROK. 1 hit.
[Graphical view]
PROSITEiPS01125. ROK. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9CMX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRYGFDIGGT KIELAVFNDQ LEKQYSERVE TPKESYEEWL NTIVRLVHKA
60 70 80 90 100
DEMFQCQGTV GLGIPGFVNP ATGIAEIVNI RAADHKPIIQ DLETRLGREV
110 120 130 140 150
RAENDANCFA LSEAWDEENA QYPSVLGLIL GTGFGGGLIF NGKVHSGQTG
160 170 180 190 200
MAGEVGHTQL NYHALRLLGG DNAPIYDCGC GNRACLDTYL SGRGFEMLYR
210 220 230 240 250
DMQGEALSAQ AIIQRFYAGD QSAVKFVELF IELCAISIGN LITVLDPHVI
260 270 280 290 300
VLGGGLSNFD YLYEALPKAL PARLLRSANV PLIKKAKYGD SGGVRGAAAL

FLSK
Length:304
Mass (Da):33,039
Last modified:June 1, 2001 - v1
Checksum:i9E6A87AF91ABF786
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004439 Genomic DNA. Translation: AAK02759.1.
RefSeqiNP_245612.1. NC_002663.1.
WP_005726560.1. NC_002663.1.

Genome annotation databases

EnsemblBacteriaiAAK02759; AAK02759; PM0675.
GeneIDi1244022.
KEGGipmu:PM0675.
PATRICi22870538. VBIPasMul88067_0684.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE004439 Genomic DNA. Translation: AAK02759.1.
RefSeqiNP_245612.1. NC_002663.1.
WP_005726560.1. NC_002663.1.

3D structure databases

ProteinModelPortaliQ9CMX5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272843.PM0675.

Proteomic databases

PRIDEiQ9CMX5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK02759; AAK02759; PM0675.
GeneIDi1244022.
KEGGipmu:PM0675.
PATRICi22870538. VBIPasMul88067_0684.

Phylogenomic databases

eggNOGiCOG1940.
HOGENOMiHOG000150087.
KOiK00884.
OMAiWIGNDAD.
OrthoDBiEOG61P6P0.

Enzyme and pathway databases

UniPathwayiUPA00544.
BioCyciPMUL272843:GC8W-697-MONOMER.

Family and domain databases

HAMAPiMF_01271. GlcNAc_kinase.
InterProiIPR023505. N-acetyl-D-glucosamine_kinase.
IPR000600. ROK.
[Graphical view]
PfamiPF00480. ROK. 1 hit.
[Graphical view]
PROSITEiPS01125. ROK. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Pm70.

Entry informationi

Entry nameiNAGK_PASMU
AccessioniPrimary (citable) accession number: Q9CMX5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: June 1, 2001
Last modified: May 27, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.