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Q9CMU1 (Q9CMU1_PASMU) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonucleoside-diphosphate reductase RuleBase RU003410
EC=1.17.4.1 RuleBase RU003410
Gene names
Name:nrdA EMBL AAK02801.1
Ordered Locus Names:PM0717
OrganismPasteurella multocida (strain Pm70) [Complete proteome] [HAMAP]
Taxonomic identifier272843 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Pasteurella

Protein attributes

Sequence length756 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides By similarity. RuleBase RU003410

Catalytic activity

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. RuleBase RU003410

Pathway

Genetic information processing; DNA replication. RuleBase RU003410

Sequence similarities

Belongs to the ribonucleoside diphosphate reductase large chain family. RuleBase RU003410

Ontologies

Keywords
   Biological processDNA replication RuleBase RU003410
   Molecular functionOxidoreductase RuleBase RU003410
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processDNA replication

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentribonucleoside-diphosphate reductase complex

Inferred from electronic annotation. Source: InterPro

   Molecular functionATP binding

Inferred from electronic annotation. Source: InterPro

ribonucleoside-diphosphate reductase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q9CMU1 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: E6F80D1053131BDF

FASTA75685,417
        10         20         30         40         50         60 
MNKALMVTKR DGHLEPIDLD KIHRVITWAA EGLDNVSVSQ VELRSHIQFY EGIRTSDIHE 

        70         80         90        100        110        120 
TIIKAAADLI SKDSPDYQYL AARLAVFHLR KKAYGHFDPP RLYDHVKKLV RMGKYDPALL 

       130        140        150        160        170        180 
VDYTREEWDE MDSYLDHWRD MTFSYAAVKQ LEGKYLVQNR VTGEIYESAQ FLYLLVAASL 

       190        200        210        220        230        240 
FSKYPTETRL SYIRRFYDAT STFKISLPTP IMAGVRTPTR QFSSCVLIEC GDSLDSINAT 

       250        260        270        280        290        300 
ASAIVKYVSQ RAGIGVNAGA IRALGSPIRG GEAFHTGCIP FYKYFQTAVK SCSQGGVRGG 

       310        320        330        340        350        360 
AATVYYPIWH LEVESLLVLK NNRGVEDNRV RHMDYGVQLN KLMYQRLIKG GDITLFSPSD 

       370        380        390        400        410        420 
VPGLYEAFFA DQDKFEQLYL QYEQDPTIRQ RSVKAVELFS LLMQERASTG RIYIQNVDHC 

       430        440        450        460        470        480 
NTHSPFDPKV APVRQSNLCL EIALPTKPLQ HFHDEKGEIA LCTLSAFNLG TLENLDELEG 

       490        500        510        520        530        540 
LADLAVRALD ALLDYQDYPV IAAKKSSLAR RSLGIGVINY AYYLAKNGVR YSDSSANDLT 

       550        560        570        580        590        600 
HRTFEAIQYY LLKASMNLAK EIGPCEYFNE TTYSQGILPI DTYKKDIDNL TKEPLHYDWE 

       610        620        630        640        650        660 
TLRKEIQEFG LRNSTLTALM PSETSSQISN ATNGIEPPRG HVSVKASKDG ILKQVVPEYE 

       670        680        690        700        710        720 
TLGENYELLW DLPNNDGYLH LVGIMQKFVD QAISANTNYD PQRFEDGKVP MKRLLGDLLT 

       730        740        750 
AYKYGLKTLY YQNTRDGAED VQEDIDDGCS GGACKI

« Hide

References

[1]"Complete genomic sequence of Pasteurella multocida Pm70."
May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V.
Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001) [PubMed: 11248100] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Pm70.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE004439 Genomic DNA. Translation: AAK02801.1.
RefSeqNP_245654.1. NC_002663.1.

3D structure databases

HSSPHSSP built from PDB template 5R1R based on UniProtKB P00452.
ProteinModelPortalQ9CMU1.
SMRQ9CMU1. Positions 5-737.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1244064.
GenomeReviewsGene locus PM0717 in contig AE004439_GR.
KEGGpmu:PM0717.
NMPDRfig|272843.1.peg.717.
PATRIC22870628. VBIPasMul88067_0725.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG297012.
OMAYELLWQM.
ProtClustDBPRK09103.

Enzyme and pathway databases

BioCycPMUL272843:PM0717-MONOMER.

Family and domain databases

InterProIPR005144. ATP-cone.
IPR013346. NrdE_NrdA.
IPR013509. Ribncl_Rdtase_lsu_N.
IPR000788. Ribncl_red_lg_C.
IPR008926. Ribnucl_Rdtase_R1-su_N.
[Graphical view]
KOK00525.
PfamPF03477. ATP-cone. 1 hit.
PF02867. Ribonuc_red_lgC. 1 hit.
PF00317. Ribonuc_red_lgN. 1 hit.
[Graphical view]
PRINTSPR01183. RIBORDTASEM1.
SUPFAMSSF48168. Ribonucleo_red_N. 1 hit.
TIGRFAMsTIGR02506. NrdE_NrdA. 1 hit.
PROSITEPS51161. ATP_CONE. 1 hit.
PS00089. RIBORED_LARGE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9CMU1_PASMU
AccessionPrimary (citable) accession number: Q9CMU1
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: December 14, 2011
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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