Reviewed, UniProtKB/Swiss-Prot Q9CMB5 (UBIC_PASMU)

Names and origin

Protein names

Recommended name:
    Probable chorismate--pyruvate lyase
      Short name=CL
      Short name=CPL
    EC=4.1.3.40

Gene names

Name:	ubiC
Ordered Locus Names:	PM0918

Organism

Pasteurella multocida [Complete proteome] [HAMAP]

Taxonomic identifier

747 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Pasteurella

Protein attributes

Sequence length	170 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity.
Catalytic activity	Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the ubiC family.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis
Cellular component	Cytoplasm
Ligand	Pyruvate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyruvate biosynthetic process Inferred from electronic annotation. Source: HAMAP ubiquinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	chorismate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 170	170	Probable chorismate--pyruvate lyase HAMAP MF_01632		PRO_0000240551
Sites
	Binding site	77	1	Substrate By similarity
	Binding site	114	1	Substrate; via amide nitrogen By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9CMB5-1 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 2C06710819BE2B5F	FASTA	170	19,506
	10 20 30 40 50 60 MSNYSQLLQN ATWQPSTDMQ LPLSISSWLE LSTSLTTQLK QAFGEVNVCV LAESWITTLN 70 80 90 100 110 120 ENERQFFPKQ ACPCWCREVI LKSQDIPLIF ARTLIPASLL TQHSELQQLG NRALGEWLFM 130 140 150 160 170 QSDRIRQKLE LTHDKNTALY ARRALMSIGA ENMMVAELFL TPQIFTRVVK

References

[1]	"Complete genomic sequence of Pasteurella multocida Pm70." May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V. Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001) [PubMed: 11248100] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Pm70.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE004439 Genomic DNA. Translation: AAK03002.1.
RefSeq	NP_245855.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1244265.
GenomeReviews	Gene locus PM0918 in contig AE004439_GR.
KEGG	pmu:PM0918.
NMPDR	fig|272843.1.peg.918.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q9CMB5.
OMA	RISLEWQ.
Enzyme and pathway databases
BRENDA	4.1.3.40. 258935.
Family and domain databases
HAMAP	MF_01632. [Tree]
InterPro	IPR007440. Chorismate--pyruvate_lyase. [Graphical view]
Pfam	PF04345. Chor_lyase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UBIC_PASMU

Accession

Primary (citable) accession number: Q9CMB5

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	June 1, 2001
Last modified:	November 3, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)