ID   Q9CM43_PASMU            Unreviewed;      1080 AA.
AC   Q9CM43;
DT   01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2001, sequence version 1.
DT   27-MAR-2024, entry version 128.
DE   RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE            EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN   OrderedLocusNames=PM1000 {ECO:0000313|EMBL:AAK03084.1};
OS   Pasteurella multocida (strain Pm70).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Pasteurella.
OX   NCBI_TaxID=272843 {ECO:0000313|EMBL:AAK03084.1, ECO:0000313|Proteomes:UP000000809};
RN   [1] {ECO:0000313|EMBL:AAK03084.1, ECO:0000313|Proteomes:UP000000809}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pm70 {ECO:0000313|EMBL:AAK03084.1,
RC   ECO:0000313|Proteomes:UP000000809};
RX   PubMed=11248100; DOI=10.1073/pnas.051634598;
RA   May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V.;
RT   "Complete genomic sequence of Pasteurella multocida Pm70.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001).
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DR   EMBL; AE004439; AAK03084.1; -; Genomic_DNA.
DR   RefSeq; WP_010906961.1; NC_002663.1.
DR   AlphaFoldDB; Q9CM43; -.
DR   STRING; 272843.PM1000; -.
DR   CAZy; GH33; Glycoside Hydrolase Family 33.
DR   EnsemblBacteria; AAK03084; AAK03084; PM1000.
DR   KEGG; pmu:PM1000; -.
DR   PATRIC; fig|272843.6.peg.1013; -.
DR   HOGENOM; CLU_286180_0_0_6; -.
DR   OrthoDB; 7294637at2; -.
DR   Proteomes; UP000000809; Chromosome.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   Gene3D; 2.40.128.130; Autotransporter beta-domain; 1.
DR   InterPro; IPR005546; Autotransporte_beta.
DR   InterPro; IPR036709; Autotransporte_beta_dom_sf.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   InterPro; IPR023364; Trans_sialidase_dom3.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF03797; Autotransporter; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SMART; SM00869; Autotransporter; 1.
DR   SUPFAM; SSF103515; Autotransporter; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
DR   PROSITE; PS51208; AUTOTRANSPORTER; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000809};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           26..1080
FT                   /note="exo-alpha-sialidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004324463"
FT   DOMAIN          818..1080
FT                   /note="Autotransporter"
FT                   /evidence="ECO:0000259|PROSITE:PS51208"
SQ   SEQUENCE   1080 AA;  121451 MW;  43E1E0F8282AEEDA CRC64;
     MKKFNPSVLA LSISSLLLTS TLTFGQIQQQ DKALFGVKEH QESLLFHQSL VKQGSDNVPI
     WRIPSLLRTK DGVLIAAADK RWQHRGDWGD IDTAIRISHD DGKTWGNITT ILDLPSQNTE
     HSPVMNTSTN PWGDKDNVIR QRIRDPNYSS QYMNSAFLID AQMVQDKRNG RVFLAVDMFP
     ESAGFFHLNG AFNNPGKDGS GRLTIDGKQY LKLIYQDKQW TLREDGSVFD ELNRKTQYKV
     IVKGDPNKNF KDLGDVYNEN NENIGNIYLT NRKGSKNEKA PFYIPTTSYL WMTYSDDNGK
     TWSSPIDISA QIKKDWMRFL GTGPGVGIQT KNGNLIFPVY YTNQNNVQST ALIISKDGGK
     SWELGQSPND KRIELNGMNS HNLRWDSWYA NTAKQKGFEL TEAQLVELEN GELKLFMRNQ
     TGKVMMSTSK DGGYTWVNTE KINELDHGYS QLSVIKYSKR INGKEYIVFS GQSRSGQGGD
     NLRRDGKLFL GEVQESGEIK WDTTNLVREI VSQGKAAGQP NGYVYSSMAE LGDGSIGLAY
     ENTTDYTTIM YLPIEMQEFF WKAGKIFSDV RQKEPLVFTY DGTETLEKIG DGIAIKRGEG
     ESQSGINVSE GLLVLDQQTK DGKNKAFTQL TLNNSGVAQV NSTQNIDRFV VNNGATGYLQ
     FTVTDTHSPR LKINQDVTAH GQIVAVQVNL QKKLKPNDKG YYHAQGEELI AFKDNGQVKW
     RLVNDELKDG MYVYTLASVA KPSVLRTTSQ PHSLYLTNKL ITADGKAVST VSPLKAPLTV
     NARPQVNPVL ASYLTANLAL NKMSEQLQQS FMHETRLLQE KDRSIFVKYL NGKQKYGSNL
     SFIDYGYDFN ASYSGVMLGG KVWQSERGNH ALYTALNKTS YKVTPKAVDG ETKAKYHSWG
     GSINWHSNLP HNLIVDLSAG YQKHKGDIEH AGHVKGYTFN IGADLGYRYQ WMKNAFITPM
     VGLHYLYASL SDVNDQANKA LLKYNNFNAL KTNLGVDVNY RIGKFEVKGL LSYDMYQQKT
     RQLYVDDVAY KQGKLADTLH LNTQFVAHLT PRFAFSTEVG FQHARNKGQS SFAVGAHYQF
//