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Q9CLY7 (MTLD_PASMU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannitol-1-phosphate 5-dehydrogenase
EC=1.1.1.17
Gene names
Name:mtlD
Ordered Locus Names:PM1062
OrganismPasteurella multocida (strain Pm70) [Complete proteome] [HAMAP]
Taxonomic identifier272843 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Pasteurella

Protein attributes

Sequence length385 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH. HAMAP MF_00196

Sequence similarities

Belongs to the mannitol dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functioncoenzyme binding

Inferred from electronic annotation. Source: InterPro

mannitol-1-phosphate 5-dehydrogenase activity

Inferred from electronic annotation. Source: EC

nucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 385385Mannitol-1-phosphate 5-dehydrogenase HAMAP MF_00196
PRO_0000170715

Regions

Nucleotide binding3 – 1412NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9CLY7 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: ABEB7345ABB52DE2

FASTA38542,595
        10         20         30         40         50         60 
MKALHFGAGN IGRGFIGKLL ADSGIQVIFA DVNDHVIEQL KTQRAYPVKI VGDRLNVIET 

        70         80         90        100        110        120 
VSNVTGVNSK NEADIIACFT EVDLVTTAVG PNVLKIISST IAKGLSARFR AGNTRPLNII 

       130        140        150        160        170        180 
ACENMVRGTS FLKDNVFSYL TPEEQQQAEA QIGFVDSAVD RIVPPVQFDP ANPLLVTVEE 

       190        200        210        220        230        240 
FSEWIVDKTQ FKGTIPAITG MEQTDNLMAF VERKLFTLNT GHATTAYLGK LKGHQFVKDS 

       250        260        270        280        290        300 
IDDPDIREAV KATMQESGAV LIKRYGFDPH AHAAYIEKIL KRFANPYLQD DVDRVGREPL 

       310        320        330        340        350        360 
RKLSYNDRLI KPLRGTLEYG LPNQHLIQTI ASALAYRNES DPQAVELAQL LQQDTLESAV 

       370        380 
KKITELTESN IVQQIVTAYN ALQKN

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References

[1]"Complete genomic sequence of Pasteurella multocida Pm70."
May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V.
Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001) [PubMed: 11248100] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Pm70.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE004439 Genomic DNA. Translation: AAK03146.1.
RefSeqNP_245999.1. NC_002663.1.

3D structure databases

ProteinModelPortalQ9CLY7.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1244409.
GenomeReviewsGene locus PM1062 in contig AE004439_GR.
KEGGpmu:PM1062.
NMPDRfig|272843.1.peg.1062.
PATRIC22871373. VBIPasMul88067_1076.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG568825.
OMAFANTAVD.
ProtClustDBPRK02318.

Enzyme and pathway databases

BioCycPMUL272843:PM1062-MONOMER.

Family and domain databases

HAMAPMF_00196. Mannitol_dehydrog.
[Tree]
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR023028. Mannitol_1_phos_5_DH.
IPR000669. Mannitol_DH.
IPR013118. Mannitol_DH_C.
IPR023027. Mannitol_DH_CS.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KOK00009.
PfamPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
PRINTSPR00084. MTLDHDRGNASE.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
PROSITEPS00974. MANNITOL_DHGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMTLD_PASMU
AccessionPrimary (citable) accession number: Q9CLY7
Entry history
Integrated into UniProtKB/Swiss-Prot: October 19, 2002
Last sequence update: June 1, 2001
Last modified: January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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