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Q9CJ84 (Q9CJ84_LACLA) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phospho-2-dehydro-3-deoxyheptonate aldolase PIRNR PIRNR001361

EC=2.5.1.54 PIRNR PIRNR001361
Alternative name(s):
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase PIRNR PIRNR001361
DAHP synthase PIRNR PIRNR001361
Phospho-2-keto-3-deoxyheptonate aldolase PIRNR PIRNR001361
Gene names
Name:Stac MGI 1201400
Synonyms:aroF EMBL AAK04214.1
Ordered Locus Names:LL0116
ORF Names:L0063 EMBL AAK04214.1
OrganismLactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Taxonomic identifier272623 [NCBI]
Taxonomic lineageBacteriaFirmicutesLactobacillalesStreptococcaceaeLactococcus

Protein attributes

Sequence length345 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) By similarity. PIRNR PIRNR001361

Catalytic activity

Phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate. PIRNR PIRNR001361

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7. PIRNR PIRNR001361

Sequence similarities

Belongs to the class-I DAHP synthase family. PIRNR PIRNR001361

Sequences

Sequence LengthMass (Da)Tools
Q9CJ84 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: C58A1F050C8A4EBB

FASTA34539,220
        10         20         30         40         50         60 
MSFKEISPKI NIDAIKMLGH LNSEQQEKKL QRDKELEAII KGEDDRLLLI IGPCSSDNEE 

        70         80         90        100        110        120 
AVLEYARRLA KLQEAVKDKI FMVMRVYTAK PRTNGDGYKG LIHEPDADGH TDLINGIKMV 

       130        140        150        160        170        180 
RDLHYKVITE TGLTTADEML YPENLPMVDD LVSYHAIGAR SVENQQHRFV ASGIDVPTGL 

       190        200        210        220        230        240 
KNPTSGNLKV MFNGIYAAQQ SQDFLFGRAE VQTSGNPLAH AILRGGQDEN GKYHPNYYTD 

       250        260        270        280        290        300 
NLLDTIEIYE KMGLKNPFIV IDTNHDNSGK KFMEQIRIVR QTLVNRDWDD KIRQNVRGFM 

       310        320        330        340 
IESYLEDGRQ DKPEVFGKSI TDPCLGWDKT EALVQEIYEA ENKNN 

« Hide

References

[1]"The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403."
Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A.
Genome Res. 11:731-753(2001) [PubMed: 11337471] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IL1403.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE005176 Genomic DNA. Translation: AAK04214.1.
PIRD86639.
RefSeqNP_266272.1. NC_002662.1.

3D structure databases

HSSPHSSP built from PDB template 1GG1 based on UniProtKB P00886.
ProteinModelPortalQ9CJ84.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1113722.
GenomeReviewsGene locus LL0116 in contig AE005176_GR.
KEGGlla:L0063.
NMPDRfig|272623.1.peg.123.
PATRIC22292384. VBILacLac136773_0130.

Phylogenomic databases

HOGENOMHBG670536.
OMAMDNSFKL.
ProtClustDBPRK09261.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR006218. DAHP1/KDSA.
IPR006219. DHAP_synth_1.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01626.
PANTHERPTHR21225. AroFGH. 1 hit.
PfamPF00793. DAHP_synth_1. 1 hit.
[Graphical view]
PIRSFPIRSF001361. DAHP_synthase. 1 hit.
TIGRFAMsTIGR00034. AroFGH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ9CJ84_LACLA
AccessionPrimary (citable) accession number: Q9CJ84
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)