Q9CJ44 (GATC_LACLA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamyl-tRNA(Gln) amidotransferase subunit C
Short name=Glu-ADT subunit C
EC=6.3.5.-

Gene names

Name:	gatC
Ordered Locus Names:	LL0162
ORF Names:	L0475

Organism

Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)

Taxonomic identifier

272623 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Lactococcus

Protein attributes

Sequence length	101 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) By similarity. HAMAP MF_00122
Catalytic activity	ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate. HAMAP MF_00122 ATP + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + phosphate + L-asparaginyl-tRNA(Asn) + L-glutamate. HAMAP MF_00122
Subunit structure	Heterotrimer of A, B and C subunits By similarity. HAMAP MF_00122
Sequence similarities	Belongs to the GatC family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	ATP-binding Nucleotide-binding
Molecular function	Ligase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	regulation of translational fidelity Inferred from electronic annotation. Source: InterPro translation Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ligase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 101	101	Glutamyl-tRNA(Gln) amidotransferase subunit C HAMAP MF_00122		PRO_0000105303

Sequences

	Sequence		Length	Mass (Da)
	Q9CJ44 [UniParc]. Last modified April 27, 2001. Version 1. Checksum: 2FC34329C2AA4966	FASTA	101	11,214
	10 20 30 40 50 60 MSQITEEQVK HVALLSKLEF SENEVKSFTD TFGKIIDMVE MLDEVDGEGV PFTMNVADNL 70 80 90 100 NFMREDVAEK GLDREKLMAA VPEKEDGFIK VPAMLSDGGD A

References

[1]

"The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403." Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A. Genome Res. 11:731-753(2001) [PubMed: 11337471] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IL1403.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE005176 Genomic DNA. Translation: AAK04260.1.
PIR	B86645.
RefSeq	NP_266318.1. NC_002662.1.
3D structure databases
ProteinModelPortal	Q9CJ44.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1113770.
GenomeReviews	Gene locus LL0162 in contig AE005176_GR.
KEGG	lla:L0475.
NMPDR	fig|272623.1.peg.169.
PATRIC	22292490. VBILacLac136773_0180.
Phylogenomic databases
HOGENOM	HBG586403.
OMA	QNVPEKE.
ProtClustDB	PRK00034.
Enzyme and pathway databases
BioCyc	LLAC272623:L0475-MONOMER.
Family and domain databases
HAMAP	MF_00122. GatC. [Tree]
InterPro	IPR003837. Glu-tRNAGlntrans. [Graphical view]
KO	K02435.
Pfam	PF02686. Glu-tRNAGln. 1 hit. [Graphical view]
TIGRFAMs	TIGR00135. GatC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GATC_LACLA

Accession

Primary (citable) accession number: Q9CJ44

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 27, 2001
Last sequence update:	April 27, 2001
Last modified:	January 25, 2012
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program