Q9CJ12 (Q9CJ12_LACLA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Glucose-1-phosphate thymidylyltransferase RuleBase RU003706
EC=2.7.7.24 RuleBase RU003706

Gene names

Name:	rmlA EMBL AAK04292.1
Ordered Locus Names:	LL0194
ORF Names:	L197041 EMBL AAK04292.1

Organism

Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)

Taxonomic identifier

272623 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Lactococcus

Protein attributes

Sequence length	289 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis By similarity. RuleBase RU003706
Catalytic activity	dTTP + alpha-D-glucose 1-phosphate = diphosphate + dTDP-glucose. RuleBase RU003706
Sequence similarities	Belongs to the glucose-1-phosphate thymidylyltransferase family. RuleBase RU003706

Ontologies

Keywords
Ligand	Magnesium RuleBase RU003706 Metal-binding RuleBase RU003706
Molecular function	Nucleotidyltransferase RuleBase RU003706 EMBL AAK04292.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	extracellular polysaccharide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	glucose-1-phosphate thymidylyltransferase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9CJ12 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 90F72C534C1D41D0	FASTA	289	32,131
	10 20 30 40 50 60 MKGIILAGGS GTRLYPLTRA ASKQLMPIYD KPMIYYPLST LMLAGIKDIL IISTPTDTPR 70 80 90 100 110 120 FKELLQDGSE FGINLQYAVQ PSPDGLAQAF IIGEEFIGDD SVALILGDNI YHGPGMSKML 130 140 150 160 170 180 QNAAAKEKGA TVFGYHVPDP ERFGVVEFDE NMNAVSIEEK PEEPKSNYAV TGLYFYDNDV 190 200 210 220 230 240 IEIAKNIEPS PRGELEITDV NKAYLERGDL SVELMGRGFA WLDTGTHESL LEAAQYIETV 250 260 270 280 QRMQNMQVAN LEEIAYRMGY ITADDVLKLA QPLKKNEYGQ YLLRLIGKD

References

[1]	"The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403." Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A. Genome Res. 11:731-753(2001) [PubMed: 11337471] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IL1403.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE005176 Genomic DNA. Translation: AAK04292.1.
PIR	B86649.
RefSeq	NP_266350.1. NC_002662.1.
3D structure databases
HSSP	HSSP built from PDB template 1H5R based on UniProtKB P37744.
ProteinModelPortal	Q9CJ12.
SMR	Q9CJ12. Positions 2-285.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1113803.
GenomeReviews	Gene locus LL0194 in contig AE005176_GR.
KEGG	lla:L197041.
NMPDR	fig|272623.1.peg.202.
PATRIC	22292560. VBILacLac136773_0215.
Phylogenomic databases
HOGENOM	HBG688195.
OMA	YRAGWID.
ProtClustDB	CLSK2517770.
Family and domain databases
InterPro	IPR005907. G1P_thy_trans_s. IPR005835. NTP_transferase. [Graphical view]
KO	K00973.
PANTHER	PTHR22572:SF13. PTHR22572:SF13. 1 hit.
Pfam	PF00483. NTP_transferase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01207. RmlA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q9CJ12_LACLA

Accession

Primary (citable) accession number: Q9CJ12

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	December 14, 2011
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)