Q9CJ08 (Q9CJ08_LACLA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
dTDP-glucose 4,6-dehydratase RuleBase RU004473
EC=4.2.1.46 RuleBase RU004473

Gene names

Name:	rmlB EMBL AAK04296.1
Ordered Locus Names:	LL0198
ORF Names:	L199221 EMBL AAK04296.1

Organism

Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)

Taxonomic identifier

272623 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Lactococcus

Protein attributes

Sequence length	349 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dTDP-glucose = dTDP-4-dehydro-6-deoxy-D-glucose + H2O. RuleBase RU004473
Cofactor	NAD By similarity. RuleBase RU004473
Sequence similarities	Belongs to the sugar epimerase family. dTDP-glucose dehydratase subfamily. RuleBase RU004473

Ontologies

Keywords
Molecular function	Lyase RuleBase RU004473
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	nucleotide-sugar metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	coenzyme binding Inferred from electronic annotation. Source: InterPro dTDP-glucose 4,6-dehydratase activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9CJ08 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 331342A508B25654	FASTA	349	39,461
	10 20 30 40 50 60 MTEFKNIVVT GGAGFIGSNF VHYVYNNHPD VHITVLDKLT YAGNVNNINM LFDSGRVELV 70 80 90 100 110 120 VGDIADPEIV DQVASKADAI VHYAAESHND NSLKSQDEFI QTNFIGTYTL IQAARKYDLR 130 140 150 160 170 180 FHHVSTDEVY GDLPYREDLP GHGEGEGEKF TDKTPYNPSS PYSSTKAASD LIVRAWVRSF 190 200 210 220 230 240 GLKATISNCS NNYGPFQHIE KFIPRQITNI LSGIKPKLYG DGKNVRDWIH TEDHSSGVWT 250 260 270 280 290 300 ILTKGRMGET YLIGADGEKN NKEVLEDILT RMGKDKDDYD RVTDRAGHDL RYAIDNSKLR 310 320 330 340 TELGWAPKHT DFESGLQATI DWYRENENWW KAEKEAVEAK YAETQKVLD

References

[1]	"The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403." Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A. Genome Res. 11:731-753(2001) [PubMed: 11337471] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IL1403.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE005176 Genomic DNA. Translation: AAK04296.1.
PIR	F86649.
RefSeq	NP_266354.1. NC_002662.1.
3D structure databases
HSSP	HSSP built from PDB template 1KEP based on UniProtKB P95780.
ProteinModelPortal	Q9CJ08.
SMR	Q9CJ08. Positions 2-348.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1113807.
GenomeReviews	Gene locus LL0198 in contig AE005176_GR.
KEGG	lla:L199221.
NMPDR	fig|272623.1.peg.206.
PATRIC	22292568. VBILacLac136773_0219.
Phylogenomic databases
HOGENOM	HBG755066.
OMA	VRDWIHA.
ProtClustDB	CLSK797013.
Family and domain databases
InterPro	IPR005888. dTDP_Gluc_deHydtase. IPR001509. Epimerase_deHydtase. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K01710.
PANTHER	PTHR10366:SF41. PTHR10366:SF41. 1 hit.
Pfam	PF01370. Epimerase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01181. DTDP_gluc_dehyt. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q9CJ08_LACLA

Accession

Primary (citable) accession number: Q9CJ08

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	December 14, 2011
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)