Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q9CIF5 (IDI2_LACLA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Isopentenyl-diphosphate delta-isomerase
Short name=IPP isomerase
EC=5.3.3.2
Alternative name(s):
Isopentenyl pyrophosphate isomerase
Gene names
Name:fni
Ordered Locus Names:LL0407
ORF Names:L11083
OrganismLactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Taxonomic identifier272623 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Streptococcaceae › Lactococcus

Protein attributes

Sequence length347 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) By similarity. HAMAP MF_00354

Catalytic activity

Isopentenyl diphosphate = dimethylallyl diphosphate. HAMAP MF_00354

Cofactor

FMN By similarity. HAMAP MF_00354

NADPH By similarity. HAMAP MF_00354

Subcellular location

Cytoplasm By similarity HAMAP MF_00354.

Sequence similarities

Belongs to the IPP isomerase type 2 family.

Ontologies

Keywords
   Biological processIsoprene biosynthesis
   Cellular componentCytoplasm
   LigandFMN
Flavoprotein
NADP
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processisoprenoid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionFMN binding

Inferred from electronic annotation. Source: InterPro

isopentenyl-diphosphate delta-isomerase activity

Inferred from electronic annotation. Source: EC

oxidoreductase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 347347Isopentenyl-diphosphate delta-isomerase HAMAP MF_00354
PRO_0000134410

Sequences

Sequence LengthMass (Da)Tools
Q9CIF5 [UniParc].

Last modified April 27, 2001. Version 1.
Checksum: CE10EDDBBA0D36E3

FASTA34738,686
        10         20         30         40         50         60 
MKTEKEIHQH RKDEHLSLAY KYWREEKNQT SGLTFSDSRI IPNSLPELST KKINFSSEVF 

        70         80         90        100        110        120 
GQNFEFPFYI EAMTGGTERA DKINAQLAEI AKNQHLAMAV GSQSIALKFP ELAAGFSEVR 

       130        140        150        160        170        180 
KIHSSGFLFA NIGAGHSLEN AKRAVDMIEA NALEIHVNTA QELPMDEGDR EFYWLENINE 

       190        200        210        220        230        240 
IASQLEVPVV VKEVGFGISQ KTFKALAKTS VSGINIGGAG GTNFAWIERK RSKNGFNLDE 

       250        260        270        280        290        300 
FGLSTLESLL EAKMADNRKS LIATGGITSA QEIFKSLILG ADLSSSAGFI LKNLMQTGPE 

       310        320        330        340 
KVEEVIEQWK QDLNKLFVLT GSKNIEECRK VELLYSINML NFIQQRK

« Hide

References

[1]"The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403."
Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A.
Genome Res. 11:731-753(2001) [PubMed: 11337471] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IL1403.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE005176 Genomic DNA. Translation: AAK04505.1.
PIRG86675.
RefSeqNP_266563.1. NC_002662.1.

3D structure databases

ProteinModelPortalQ9CIF5.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1114018.
GenomeReviewsGene locus LL0407 in contig AE005176_GR.
KEGGlla:L11083.
NMPDRfig|272623.1.peg.415.
PATRIC22293020. VBILacLac136773_0441.

Phylogenomic databases

HOGENOMHBG354479.
OMAGSQRAAI.
ProtClustDBPRK05437.

Enzyme and pathway databases

BioCycLLAC272623:L11083-MONOMER.

Family and domain databases

HAMAPMF_00354. Idi_2.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR000262. FMN-dep_DH.
IPR011179. IPdP_isomerase.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01823.
PANTHERPTHR10578:SF3. IPdP_isomerase. 1 hit.
PfamPF01070. FMN_dh. 1 hit.
[Graphical view]
PIRSFPIRSF003314. IPP_isomerase. 1 hit.
TIGRFAMsTIGR02151. IPP_isom_2. 1 hit.
ProtoNetSearch...

Entry information

Entry nameIDI2_LACLA
AccessionPrimary (citable) accession number: Q9CIF5
Entry history
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: April 27, 2001
Last modified: January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents