Q9CHT4 (RPOE_LACLA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable DNA-directed RNA polymerase subunit delta

Alternative name(s):
RNAP delta factor

Gene names

Name:	rpoE
Ordered Locus Names:	LL0634
ORF Names:	L0141

Organism

Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)

Taxonomic identifier

272623 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Lactococcus

Protein attributes

Sequence length	187 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling By similarity. HAMAP MF_00357
Subunit structure	RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors By similarity.
Sequence similarities	Belongs to the rpoE family.

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 187	187	Probable DNA-directed RNA polymerase subunit delta HAMAP MF_00357		PRO_0000204313
Regions
	Compositional bias	118 – 187	70	Asp/Glu-rich (acidic) HAMAP MF_00357

Sequences

	Sequence		Length	Mass (Da)
	Q9CHT4 [UniParc]. Last modified May 4, 2001. Version 1. Checksum: 2A8E30B4BCFD58C7	FASTA	187	21,387
	10 20 30 40 50 60 MKITALEGQK ISELSMIEVA HALLEQNGKE MQFSEIIRAI QDYLEKSDDE IKASISRFYT 70 80 90 100 110 120 EINTDGSFIP LGNNIWALRS WYAIDEIDEE VIALDEIEDE EEEKPAKKRK KVNAFGIEDE 130 140 150 160 170 180 IDPEDEEGTK ETTEEDMSYD TQAEDEDKDD VAAYDAELAE VELDNVDEEV DIDVEDDEDD SDDTDED

References

[1]

"The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403." Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A. Genome Res. 11:731-753(2001) [PubMed: 11337471] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IL1403.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE005176 Genomic DNA. Translation: AAK04732.1.
PIR	B86704.
RefSeq	NP_266790.1. NC_002662.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1114254.
GenomeReviews	Gene locus LL0634 in contig AE005176_GR.
KEGG	lla:L0141.
NMPDR	fig|272623.1.peg.649.
PATRIC	22293542. VBILacLac136773_0678.
Phylogenomic databases
HOGENOM	HBG535252.
OMA	TDMNTDG.
ProtClustDB	PRK02363.
Enzyme and pathway databases
BioCyc	LLAC272623:L0141-MONOMER.
Family and domain databases
HAMAP	MF_00357. RNApol_bact_RpoE. [Tree]
InterPro	IPR007759. DNA-dir_RNA_pol_delta. [Graphical view]
KO	K03048.
Pfam	PF05066. RNA_pol_delta. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RPOE_LACLA

Accession

Primary (citable) accession number: Q9CHT4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 4, 2001
Last sequence update:	May 4, 2001
Last modified:	January 25, 2012
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program