Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q9CHQ4 (Q9CHQ4_LACLA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446
EC=1.1.1.42 RuleBase RU004446
Gene names
Name:icd EMBL AAK04770.1
Ordered Locus Names:LL0672
ORF Names:L71075 EMBL AAK04770.1
OrganismLactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Taxonomic identifier272623 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Streptococcaceae › Lactococcus

Protein attributes

Sequence length412 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
Q9CHQ4 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 6FAC5BCC9A522CA0

FASTA41245,789
        10         20         30         40         50         60 
MKIEMKNGKL VVPDYPAIGY IRGDGVGEDI FPQAQKVFDA AVLKIYGQKK KIEWQKLLAG 

        70         80         90        100        110        120 
GEAFETCGEY LPKETLAHIN ENLIAIKGPL MTPVGESFRS INVTLRQKMD LYACVRPVEY 

       130        140        150        160        170        180 
FKGIKSPVKA PEKVDMTIFR ENTEDIYAGI EFASETNESH NLLKFLEKEL NVHSIRFPKT 

       190        200        210        220        230        240 
SALGIKPVSP EGSKRLVNAA FEYALKMNKK RVTFVHKGNI MKFTEGGFRN WAYEVAREYP 

       250        260        270        280        290        300 
TFTKLEYDEI KNERGSLQAE NEKKAALKSG KIYVDDVIAD NFLQQIILNP ENFEVIATLN 

       310        320        330        340        350        360 
LNGDYISDAL AAQVGGIGIA PGANINYKSG HAIFEATHGT APDIAGKNIA NPSSLILSGV 

       370        380        390        400        410 
MMFEYLGWQE VAELIKIALS FSFRNGNLTA DLGGKLSTSK FSDVLIDFIK TY

« Hide

References

[1]"The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403."
Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A.
Genome Res. 11:731-753(2001) [PubMed: 11337471] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IL1403.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE005176 Genomic DNA. Translation: AAK04770.1.
PIRH86708.
RefSeqNP_266828.1. NC_002662.1.

3D structure databases

HSSPHSSP built from PDB template 1HQS based on UniProtKB P39126.
ProteinModelPortalQ9CHQ4.
SMRQ9CHQ4. Positions 2-409.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1114296.
GenomeReviewsGene locus LL0672 in contig AE005176_GR.
KEGGlla:L71075.
NMPDRfig|272623.1.peg.690.
PATRIC22293624. VBILacLac136773_0719.

Phylogenomic databases

HOGENOMHBG518924.
OMAFQQIQTR.
ProtClustDBCLSK697344.

Family and domain databases

InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
Gene3DG3DSA:3.40.718.10. IDH_IMDH. 1 hit.
KOK00031.
PANTHERPTHR11835. IDH_IMDH_dimeric. 1 hit.
PTHR11835:SF1. NADP_IDH_prok. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9CHQ4_LACLA
AccessionPrimary (citable) accession number: Q9CHQ4
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: December 14, 2011
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info