Q9CHN1 (GLGC_LACLA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glucose-1-phosphate adenylyltransferase
EC=2.7.7.27

Alternative name(s):
ADP-glucose pyrophosphorylase
Short name=ADPGlc PPase
ADP-glucose synthase

Gene names

Name:	glgC
Ordered Locus Names:	LL0697
ORF Names:	L95975

Organism

Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)

Taxonomic identifier

272623 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Lactococcus

Protein attributes

Sequence length	380 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans By similarity. HAMAP MF_00624
Catalytic activity	ATP + alpha-D-glucose 1-phosphate = diphosphate + ADP-glucose. HAMAP MF_00624
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00624
Sequence similarities	Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glycogen biosynthesis Glycogen metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glucose-1-phosphate adenylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 380	380	Glucose-1-phosphate adenylyltransferase HAMAP MF_00624		PRO_0000195301

Sequences

	Sequence		Length	Mass (Da)
	Q9CHN1 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 524E9934E69CF6F8	FASTA	380	42,053
	10 20 30 40 50 60 MAIEMLGLIL AGGQGTRLGK LTKDVAKPAV PFGGRYRIID FALSNCANSN VKNVGVITQY 70 80 90 100 110 120 QPLTLNAHIG NGAPWGLNGI NSGVTILQPY SSQEGSKWFE GTSHAVYQNI SYIDQQNPEY 130 140 150 160 170 180 VLILSGDHIY KMDYEAMLES HKEREASLTV SVMEVPLEEA SRFGIMNTDD NDRIIEFEEK 190 200 210 220 230 240 PKEPKSNLAS MGIYIFNWKR LREVLVNGYS KGNPMEDFGG DVIPAYIEAG ENVFAYRFKG 250 260 270 280 290 300 YWKDVGTIDS LHQSSMEFLD LNNELNITDK SWRIYSHNDI SAPQFITEKS NVKNALVGDG 310 320 330 340 350 360 CYVDGTVLHS ILSQNVHVQE GTVIEDSFIM SGTFIGENVT IKNAIIGENA KIGDNVEIIG 370 380 ENEVAVIGHG EIKGENKNEQ

References

[1]	"The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403." Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A. Genome Res. 11:731-753(2001) [PubMed: 11337471] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IL1403.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE005176 Genomic DNA. Translation: AAK04795.1.
PIR	A86712.
RefSeq	NP_266853.1. NC_002662.1.
3D structure databases
ProteinModelPortal	Q9CHN1.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1114322.
GenomeReviews	Gene locus LL0697 in contig AE005176_GR.
KEGG	lla:L95975.
NMPDR	fig|272623.1.peg.715.
PATRIC	22293682. VBILacLac136773_0748.
Phylogenomic databases
HOGENOM	HBG703946.
OMA	DPLMLAR.
ProtClustDB	PRK05293.
Enzyme and pathway databases
BioCyc	LLAC272623:L95975-MONOMER.
Family and domain databases
HAMAP	MF_00624. GlgC. [Tree]
InterPro	IPR005836. ADP_Glu_pyroP_CS. IPR011831. GlgC. IPR023049. GlgC_bac. IPR001451. Hexapep_transf. IPR005835. NTP_transferase. IPR011004. Trimer_LpxA-like. [Graphical view]
KO	K00975.
Pfam	PF00132. Hexapep. 1 hit. PF00483. NTP_transferase. 1 hit. [Graphical view]
SUPFAM	SSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMs	TIGR02091. GlgC. 1 hit.
PROSITE	PS00808. ADP_GLC_PYROPHOSPH_1. 1 hit. PS00809. ADP_GLC_PYROPHOSPH_2. 1 hit. PS00810. ADP_GLC_PYROPHOSPH_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLGC_LACLA

Accession

Primary (citable) accession number: Q9CHN1

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 25, 2003
Last sequence update:	June 1, 2001
Last modified:	January 25, 2012
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program