Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q9CHF6 (Q9CHF6_LACLA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
3-oxoacyl-[acyl-carrier-protein] synthase 2 PIRNR PIRNR000447
EC=2.3.1.179 PIRNR PIRNR000447
Gene names
Name:fabF EMBL AAK04873.1
Ordered Locus Names:LL0775
ORF Names:L0186 EMBL AAK04873.1
OrganismLactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Taxonomic identifier272623 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Streptococcaceae › Lactococcus

Protein attributes

Sequence length409 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP By similarity. PIRNR PIRNR000447

Catalytic activity

(Z)-hexadec-11-enoyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-carrier-protein] + CO2 + [acyl-carrier-protein]. PIRNR PIRNR000447

Pathway

Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000447

Sequence similarities

Belongs to the beta-ketoacyl-ACP synthases family. PIRNR PIRNR000447 RuleBase RU003694

Sequences

Sequence LengthMass (Da)Tools
Q9CHF6 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 773B29D8D8BA95C5

FASTA40942,474
        10         20         30         40         50         60 
MTNRVVISGY GVVSAIGNSP EEFWNNLKAG KTGIGPITHF DAEATGISVA AEVKEFPFDK 

        70         80         90        100        110        120 
YFQKKDARRM DTFSLYAVYA ALDAMEMSGI TEENTNFDRL GCIMASGIGG LEQSQKNSQA 

       130        140        150        160        170        180 
IVAKGPRKGV APLYVPLAIA NMATGNVALR TGARGVSRAE VTACAAGANS IGSAFREIKH 

       190        200        210        220        230        240 
GYADAMIAGG AEAAICELGI AGFANLTALT KETDPEKACI PFDKNRSGFV MGEGSGVLIL 

       250        260        270        280        290        300 
ESLEHAQARG ANILAEIVGY GNTNDAFHMT TPSGVGAENA IKLALEEAGA SPADVDYVNA 

       310        320        330        340        350        360 
HGTSTHANEE TESKAIHNVI GDKAYVSSTK ALHGHALGAT GAIEAVATVQ ALLNQYAPVN 

       370        380        390        400 
AGTTELDEGM TINVVLGEGK PADINLALSQ DFGFGGHNAV LAFKKWTGE

« Hide

References

[1]"The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403."
Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A.
Genome Res. 11:731-753(2001) [PubMed: 11337471] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IL1403.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE005176 Genomic DNA. Translation: AAK04873.1.
PIRG86721.
RefSeqNP_266931.1. NC_002662.1.

3D structure databases

HSSPHSSP built from PDB template 1OX0 based on UniProtKB Q9FBC2.
ProteinModelPortalQ9CHF6.
SMRQ9CHF6. Positions 2-407.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1114402.
GenomeReviewsGene locus LL0775 in contig AE005176_GR.
KEGGlla:L0186.
NMPDRfig|272623.1.peg.795.
PATRIC22293846. VBILacLac136773_0830.

Phylogenomic databases

HOGENOMHBG757733.
OMATHANEET.
ProtClustDBCLSK697407.

Family and domain databases

InterProIPR017568. 3-oxoacyl-ACP_synth-2.
IPR000794. Beta-ketoacyl_synthase.
IPR014031. Ketoacyl_synth_C.
IPR014030. Ketoacyl_synth_N.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
Gene3DG3DSA:3.40.47.10. Thiolase-like_subgr. 2 hits.
KOK09458.
PANTHERPTHR11712. Ketoacyl_synth. 1 hit.
PfamPF00109. ketoacyl-synt. 1 hit.
PF02801. Ketoacyl-synt_C. 1 hit.
[Graphical view]
PIRSFPIRSF000447. KAS_II. 1 hit.
SUPFAMSSF53901. Thiolase-like. 2 hits.
TIGRFAMsTIGR03150. FabF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ9CHF6_LACLA
AccessionPrimary (citable) accession number: Q9CHF6
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: December 14, 2011
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info