Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q9CHF1 (Q9CHF1_LACLA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesSubmitted name:
Acetyl-CoA carboxylase carboxyl transferase subunit alpha EMBL AAK04878.1
EC=6.4.1.2 EMBL AAK04878.1
Gene names
Name:accA EMBL AAK04878.1
Ordered Locus Names:LL0780
ORF Names:L0190 EMBL AAK04878.1
OrganismLactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Taxonomic identifier272623 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Streptococcaceae › Lactococcus

Protein attributes

Sequence length260 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA By similarity. SAAS SAAS011763

Catalytic activity

ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA. SAAS SAAS011763

Pathway

Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1. SAAS SAAS011763

Subunit structure

Acetyl-CoA carboxylase is an heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD) By similarity. SAAS SAAS011763

Subcellular location

Cytoplasm By similarity SAAS SAAS011763.

Sequences

Sequence LengthMass (Da)Tools
Q9CHF1 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: EB7B4D247872BEA1

FASTA26028,546
        10         20         30         40         50         60 
MSETIDSLTG EVSQKNIADI INEARAADRI SARDIIDKVF TDFFELHGDR QLTDDEAIVG 

        70         80         90        100        110        120 
GIARFNNQAV TVIGIQKGRN LAENLATNFG QPSPNGYRKA LRLMKQAEKF GRPVITFINT 

       130        140        150        160        170        180 
AGAYPGIEAE ERGQGEAIAR NLLEMSDLKV PIIAFITGEG GSGGALALAL ANKVYILENA 

       190        200        210        220        230        240 
VYSVLSPEGF ATILWKDGSR RDEAAELMKI TAPHLLEMGL VDAIISEENL KRQLTESLGD 

       250        260 
LSLLTETELA EQRYERFRKY

« Hide

References

[1]"The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403."
Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A.
Genome Res. 11:731-753(2001) [PubMed: 11337471] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IL1403.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE005176 Genomic DNA. Translation: AAK04878.1.
PIRD86722.
RefSeqNP_266936.1. NC_002662.1.

3D structure databases

ProteinModelPortalQ9CHF1.
SMRQ9CHF1. Positions 20-260.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1114407.
GenomeReviewsGene locus LL0780 in contig AE005176_GR.
KEGGlla:L0190.
NMPDRfig|272623.1.peg.800.
PATRIC22293856. VBILacLac136773_0835.

Phylogenomic databases

HOGENOMHBG286557.
OMAFHRPIVT.
ProtClustDBCLSK697408.

Family and domain databases

InterProIPR001095. Acetyl_CoA_COase_a_su.
IPR011763. COA_CT_C.
[Graphical view]
KOK01962.
PANTHERPTHR22855:SF3. Ac-CoA_carboxylA. 1 hit.
PfamPF03255. ACCA. 1 hit.
[Graphical view]
PRINTSPR01069. ACCCTRFRASEA.
TIGRFAMsTIGR00513. AccA. 1 hit.
PROSITEPS50989. COA_CT_CTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9CHF1_LACLA
AccessionPrimary (citable) accession number: Q9CHF1
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: December 14, 2011
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info