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Protein

UvrABC system protein C

Gene

uvrC

Organism
Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:LL0840
ORF Names:L0258
OrganismiLactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Taxonomic identifieri272623 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus
Proteomesi
  • UP000002196 Componenti: Chromosome

Subcellular locationi

Q9CH98:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001383071 – 668UvrABC system protein CAdd BLAST668

Proteomic databases

PaxDbiQ9CH98.

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Protein-protein interaction databases

STRINGi272623.L0258.

Structurei

3D structure databases

ProteinModelPortaliQ9CH98.
SMRiQ9CH98.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 91GIY-YIGUniRule annotationAdd BLAST78
Domaini196 – 231UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CII. Bacteria.
COG0322. LUCA.
HOGENOMiHOG000279960.
KOiK03703.
OMAiLFPIRQC.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC. 1 hit.
InterProiView protein in InterPro
IPR000305. GIY-YIG_endonuc.
IPR035901. GIY-YIG_endonuc_sf.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR036876. UVR_dom_sf.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
PfamiView protein in Pfam
PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
SMARTiView protein in SMART
SM00465. GIYc. 1 hit.
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiView protein in PROSITE
PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9CH98-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQTIKAKLE LLPDSPGCYL HKDKNGTVIY VGKAKNLKNR VRSYFHGSHN
60 70 80 90 100
TKTELLVSEI EDLEWIVVGS NIESLVLEIN LIQRYKPKYN IMLKDDKYYP
110 120 130 140 150
FLKITNEKYP RLLVVRKVQK DGATYFGPYP DVKAANEVKR LLDRIFPFRK
160 170 180 190 200
CGLHEKKVCF YFHIHQCLCP VVNHVDPQVF KDMTQEVKEF LTGSDKKIVN
210 220 230 240 250
ELEAKMMVSS DNMEFEQAAE YRDVIKAIGT LRTKQRVMNQ DLKDRDVFGY
260 270 280 290 300
YVDKGWMCVQ VFFVRQGKLI QRDVNMFPYY NDAEEDFLTY IGQFYQDNNH
310 320 330 340 350
MMPREIFIPQ DIDKESVEAV VAASQEGNLL TKAQAKEVDA KVFTAKTLKF
360 370 380 390 400
SDQKDVEQSI VKLDKELSAE KRLSSLLAKT QIVQPSRGEK KQLVNMATKN
410 420 430 440 450
AQSQLQLKFD VAERDILKTT KAVENLGKIL GIPKPVRIES FDNSNIMGTS
460 470 480 490 500
PVSAMVVFID GKPSKKDYRK YKIKTVVGAD DYASMREVMT RRYSRALKEE
510 520 530 540 550
TALPDLIAMD GGAGQVNITK QVLKELGLSI PVAGMQKNDK HQTSELLFGD
560 570 580 590 600
PLDVVPLSRQ SQEFFLLTRI QDEVHRFAIT FHRQLRGKNT FSSKLDGIVG
610 620 630 640 650
LGPKRKQKLL TTFKNLKAIE EASVQEVAEA DIPYEVAERV KTTLSGPIQE
660
NENWESLKDN VPLLEGKK
Length:668
Mass (Da):76,425
Last modified:April 27, 2001 - v1
Checksum:i5A1BB5EF83DB042E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005176 Genomic DNA. Translation: AAK04938.1.
PIRiH86729.
RefSeqiNP_266996.1. NC_002662.1.
WP_010905584.1. NC_002662.1.

Genome annotation databases

EnsemblBacteriaiAAK04938; AAK04938; L0258.
GeneIDi1114468.
KEGGilla:L0258.
PATRICifig|272623.7.peg.899.

Similar proteinsi

Entry informationi

Entry nameiUVRC_LACLA
AccessioniPrimary (citable) accession number: Q9CH98
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: April 27, 2001
Last modified: October 25, 2017
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families