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Q9CEV7 (PEPF_LACLA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Oligoendopeptidase F homolog
EC=3.4.24.-
Gene names
Name:pepF
Ordered Locus Names:LL1727
ORF Names:L166370
OrganismLactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis) [Reference proteome] [HAMAP]
Taxonomic identifier272623 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Lactococcus ›

Protein attributes

Sequence length601 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Hydrolyzes peptides containing between 7 and 17 amino acids with a rather wide specificity By similarity.

Cofactor

Binds 1 zinc ion By similarity.

Sequence similarities

Belongs to the peptidase M3 family.

Ontologies

Keywords
   LigandMetal-binding
Zinc
   Molecular functionHydrolase
Metalloprotease
Protease
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processproteolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionmetalloendopeptidase activity

Inferred from electronic annotation. Source: InterPro

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 601601Oligoendopeptidase F homolog
PRO_0000078162

Sites

Active site3881 By similarity
Metal binding3871Zinc; catalytic By similarity
Metal binding3911Zinc; catalytic By similarity
Metal binding3941Zinc; catalytic By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9CEV7 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 045E6873F10FE19A

FASTA60169,884
        10         20         30         40         50         60 
MAKNRNEITE KLTWDLTTIY KTDKEWEAEL TRIKSELSLV EETDPGHLLD SAESLLTITE 

        70         80         90        100        110        120 
KMLSISQQVE KLYVYASMKN DQDTREAKYQ EYQSKATALY VKFGEVYAFY EPEFLKISKE 

       130        140        150        160        170        180 
VYNKWLGELQ KLKNYDHMFE RLFAKKAHIL SQKEEKLLAA AGEIFESPSE TFEIFDNADI 

       190        200        210        220        230        240 
KLPMVKNESD EMIQLTHGNY SSLMESKNRG VRKAAYKALY SNYEQYQHTY AKTLQTNVKV 

       250        260        270        280        290        300 
HNLKAQIRSY DSARQAALAN NFVPEKVYDV LMEAIHQHLP LLHRYIELRK KILGITDLKM 

       310        320        330        340        350        360 
YDIYTPLSNL DYKFNYEDGV KKAEEVLAIF GKEYKGKVKA AFEQRWIDVE ENIGKRSGAY 

       370        380        390        400        410        420 
SGGSYDTNAF MLLNWQETLD DLFTLVHEMG HSMHSAFTRE NQPYVYGDYP IFLAEIASTT 

       430        440        450        460        470        480 
NENILTETLL KESKDDKERF ALLNHWLDSF RGTVFRQSQF AEFEQKIHEA DAAGEVLTSE 

       490        500        510        520        530        540 
YLNSLYGEIN EKYYNLAAKE NPEIQYEWAR IPHFYYNFYV FQYATGFAAA TFLAEKVVHG 

       550        560        570        580        590        600 
STEDRQKYLE YLKAGSSAYP LEVIAKAGVD MESTDYLDAA FELFENRLSE LEKLVEKGVH 


L

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References

[1]"The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403."
Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A.
Genome Res. 11:731-753(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IL1403.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE005176 Genomic DNA. Translation: AAK05825.1.
PIRG86840.
RefSeqNP_267883.1. NC_002662.1.

3D structure databases

ProteinModelPortalQ9CEV7.
ModBaseSearch...

Protein-protein interaction databases

STRING272623.L166370.

Protein family/group databases

MEROPSM03.007.

PTM databases

PhosSiteP0809327.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK05825; AAK05825; L166370.
GeneID1115390.
KEGGlla:L166370.
PATRIC22295894. VBILacLac136773_1852.

Phylogenomic databases

eggNOGCOG1164.
HOGENOMHOG000059490.
KOK08602.
OMAMFAEFEL.
ProtClustDBCLSK876915.

Enzyme and pathway databases

BioCycLLAC272623:GHSH-1870-MONOMER.

Family and domain databases

Gene3D3.40.390.10. 1 hit.
InterProIPR024079. MetalloPept_cat_dom.
IPR001567. Pept_M3A_M3B.
IPR004438. Peptidase_M3B.
IPR013647. Peptidase_M3B_oligopepF_N.
[Graphical view]
PfamPF01432. Peptidase_M3. 1 hit.
PF08439. Peptidase_M3_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR00181. pepF. 1 hit.
PROSITEPS00142. ZINC_PROTEASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePEPF_LACLA
AccessionPrimary (citable) accession number: Q9CEV7
Entry history
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: June 1, 2001
Last modified: May 1, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Peptidase families

Classification of peptidase families and list of entries

SIMILARITY comments

Index of protein domains and families

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