Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9CET9

- TYRA_LACLA

UniProt

Q9CET9 - TYRA_LACLA

Protein

Prephenate dehydrogenase

Gene

tyrA

Organism
Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 87 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Prephenate + NAD+ = 4-hydroxyphenylpyruvate + CO2 + NADH.

    Pathwayi

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi3 – 3331NADSequence AnalysisAdd
    BLAST

    GO - Molecular functioni

    1. amino acid binding Source: InterPro
    2. prephenate dehydrogenase (NADP+) activity Source: InterPro
    3. prephenate dehydrogenase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tyrosine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tyrosine biosynthesis

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciLLAC272623:GHSH-1850-MONOMER.
    UniPathwayiUPA00122; UER00961.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Prephenate dehydrogenase (EC:1.3.1.12)
    Short name:
    PDH
    Gene namesi
    Name:tyrA
    Ordered Locus Names:LL1745
    ORF Names:L0058
    OrganismiLactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
    Taxonomic identifieri272623 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus
    ProteomesiUP000002196: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 354354Prephenate dehydrogenasePRO_0000119193Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272623.L0058.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9CET9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini2 – 283282Prephenate/arogenate dehydrogenasePROSITE-ProRule annotationAdd
    BLAST
    Domaini287 – 35468ACTPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 ACT domain.PROSITE-ProRule annotation
    Contains 1 prephenate/arogenate dehydrogenase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0287.
    HOGENOMiHOG000043494.
    KOiK04517.
    OMAiHAMAGTH.
    OrthoDBiEOG6B8XMB.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    InterProiIPR008927. 6-PGluconate_DH_C-like.
    IPR002912. ACT_dom.
    IPR016040. NAD(P)-bd_dom.
    IPR003099. Prephen_DH.
    [Graphical view]
    PfamiPF02153. PDH. 1 hit.
    [Graphical view]
    SUPFAMiSSF48179. SSF48179. 1 hit.
    PROSITEiPS51671. ACT. 1 hit.
    PS51176. PDH_ADH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9CET9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKKILIIGLG LIGSSIALGI KRAHPDFEIL GSDRENIQEI AQKRGIIDSK    50
    VSLVEGAQKA DIIILAVPII TTLELLKKLA TLNLKKGLLI TDTGSTKSEI 100
    VELANQLFDE DKVRFIGGHP MAGSHKSGVM AADINLFENA YYVLTQENQE 150
    LRDLLKGLHA KFIILDAKEH DRVTGQVSHF PHILASALVW QSDDFSKEHP 200
    LVKHLAAGGF RDLTRIAEAD SLMWTSVLLS NPEITIDRIE NFKKQLDEIA 250
    LKIANKDSAA IEHFFEQGKK IRQAMEIHKG ALPNFYDLFI SVPDEKGVVL 300
    KVLGLLEDFS ITNVKINEEN REDIHGQLQI SFKRAEDLKE AREIIEKATD 350
    FTVV 354
    Length:354
    Mass (Da):39,496
    Last modified:June 1, 2001 - v1
    Checksum:i766A20C932A627E2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE005176 Genomic DNA. Translation: AAK05843.1.
    PIRiA86843.
    RefSeqiNP_267901.1. NC_002662.1.

    Genome annotation databases

    EnsemblBacteriaiAAK05843; AAK05843; L0058.
    GeneIDi1115408.
    KEGGilla:L0058.
    PATRICi22295932. VBILacLac136773_1871.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE005176 Genomic DNA. Translation: AAK05843.1 .
    PIRi A86843.
    RefSeqi NP_267901.1. NC_002662.1.

    3D structure databases

    ProteinModelPortali Q9CET9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272623.L0058.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK05843 ; AAK05843 ; L0058 .
    GeneIDi 1115408.
    KEGGi lla:L0058.
    PATRICi 22295932. VBILacLac136773_1871.

    Phylogenomic databases

    eggNOGi COG0287.
    HOGENOMi HOG000043494.
    KOi K04517.
    OMAi HAMAGTH.
    OrthoDBi EOG6B8XMB.

    Enzyme and pathway databases

    UniPathwayi UPA00122 ; UER00961 .
    BioCyci LLAC272623:GHSH-1850-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    InterProi IPR008927. 6-PGluconate_DH_C-like.
    IPR002912. ACT_dom.
    IPR016040. NAD(P)-bd_dom.
    IPR003099. Prephen_DH.
    [Graphical view ]
    Pfami PF02153. PDH. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48179. SSF48179. 1 hit.
    PROSITEi PS51671. ACT. 1 hit.
    PS51176. PDH_ADH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403."
      Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A.
      Genome Res. 11:731-753(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: IL1403.

    Entry informationi

    Entry nameiTYRA_LACLA
    AccessioniPrimary (citable) accession number: Q9CET9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 26, 2001
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 87 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3