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Q9CEF5 (PKNB_LACLA) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable serine/threonine-protein kinase PknB

EC=2.7.11.1
Gene names
Name:pknB
Ordered Locus Names:LL1887
ORF Names:L138452
OrganismLactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis) [Reference proteome] [HAMAP]
Taxonomic identifier272623 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus

Protein attributes

Sequence length627 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 3 PASTA domains.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 627627Probable serine/threonine-protein kinase PknB
PRO_0000171200

Regions

Domain12 – 275264Protein kinase
Domain361 – 42868PASTA 1
Domain430 – 50273PASTA 2
Domain503 – 57472PASTA 3
Nucleotide binding18 – 269ATP By similarity
Compositional bias579 – 62749Ser-rich

Sites

Active site1361Proton acceptor By similarity
Binding site421ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9CEF5 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 00B30B68C5C28A81

FASTA62767,878
        10         20         30         40         50         60 
MIQIGKIFAD RYRIIKEIGR GGMANVYQGE DTFLGDRLVA IKVLRSNFEN DDIAIARFQR 

        70         80         90        100        110        120 
EAFAMAELSH PNIVGISDVG EFESQQYIVM EFVDGMTLKQ YINQNAPLAN DEAIEIITEI 

       130        140        150        160        170        180 
LSAMDMAHSH GIIHRDLKPQ NVLVSSSGTV KVTDFGIAKA LSETSLTQTN TMFGSVHYLS 

       190        200        210        220        230        240 
PEQARGSNAT VQSDIYAIGI ILFELLTGQI PFDGDSAVAI ALKHFQESIP SIINLNPEVP 

       250        260        270        280        290        300 
QALENVVIKA TAKDIKNRYT DVEEMMTDVA TSTSLDRRGE EKLVFNKDHD ETKIMPANLI 

       310        320        330        340        350        360 
NPYDTKPLID KKEDNDSQTD EKAASSEVGN KNKKSKKGLI IGLIILLLVV GGATLAWVVS 

       370        380        390        400        410        420 
TPTNVKIPNV TNSTLSQAKS KIKDAKLKVG TVHKQQSSTI AEGKVIKTDP TSGTTVRSNS 

       430        440        450        460        470        480 
SVDIYVSTGN EDIIKMKDFV GEKIDEAMAT LLKDYGIDES QVTQTSVPSD SYPAGTIIKQ 

       490        500        510        520        530        540 
SPKKGSSFDT KGSEKITFEV SSGKQVEVPD YKPNGQYMTY SQYQAALKAA GFTNITLDPQ 

       550        560        570        580        590        600 
ATTNQQADGY VYSVYPNVGT SVDPTQEIVV TYSVYTAPSS SSTTSESTTT SETSSSTTSS 

       610        620 
TSSSTTSQPS TDNNNSSKES STTSSSS 

« Hide

References

[1]"The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403."
Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A.
Genome Res. 11:731-753(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IL1403.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE005176 Genomic DNA. Translation: AAK05985.1.
PIRG86860.
RefSeqNP_268044.1. NC_002662.1.

3D structure databases

ProteinModelPortalQ9CEF5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272623.L138452.

PTM databases

PhosSiteP0810478.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK05985; AAK05985; L138452.
GeneID1115552.
KEGGlla:L138452.
PATRIC22296232. VBILacLac136773_2021.

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000037186.
KOK08884.
OMATGKDPGT.
OrthoDBEOG6B35XT.
ProtClustDBCLSK698007.

Enzyme and pathway databases

BioCycLLAC272623:GHSH-1994-MONOMER.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR005543. PASTA.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00740. PASTA. 3 hits.
[Graphical view]
SUPFAMSSF56112. SSF56112. 2 hits.
PROSITEPS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKNB_LACLA
AccessionPrimary (citable) accession number: Q9CEF5
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: June 1, 2001
Last modified: November 13, 2013
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families