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Protein

Probable serine/threonine-protein kinase PknB

Gene

pknB

Organism
Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei42 – 421ATPPROSITE-ProRule annotation
Active sitei136 – 1361Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi18 – 269ATPPROSITE-ProRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciLLAC272623:GHSH-1994-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable serine/threonine-protein kinase PknB (EC:2.7.11.1)
Gene namesi
Name:pknB
Ordered Locus Names:LL1887
ORF Names:L138452
OrganismiLactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Taxonomic identifieri272623 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus
ProteomesiUP000002196 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 627627Probable serine/threonine-protein kinase PknBPRO_0000171200Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272623.L138452.

Structurei

3D structure databases

ProteinModelPortaliQ9CEF5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini12 – 275264Protein kinasePROSITE-ProRule annotationAdd
BLAST
Domaini361 – 42868PASTA 1PROSITE-ProRule annotationAdd
BLAST
Domaini430 – 50273PASTA 2PROSITE-ProRule annotationAdd
BLAST
Domaini503 – 57472PASTA 3PROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi579 – 62749Ser-richAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 3 PASTA domains.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000037186.
KOiK08884.
OMAiPVCHALQ.
OrthoDBiEOG6B35XT.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00740. PASTA. 3 hits.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 2 hits.
PROSITEiPS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9CEF5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIQIGKIFAD RYRIIKEIGR GGMANVYQGE DTFLGDRLVA IKVLRSNFEN
60 70 80 90 100
DDIAIARFQR EAFAMAELSH PNIVGISDVG EFESQQYIVM EFVDGMTLKQ
110 120 130 140 150
YINQNAPLAN DEAIEIITEI LSAMDMAHSH GIIHRDLKPQ NVLVSSSGTV
160 170 180 190 200
KVTDFGIAKA LSETSLTQTN TMFGSVHYLS PEQARGSNAT VQSDIYAIGI
210 220 230 240 250
ILFELLTGQI PFDGDSAVAI ALKHFQESIP SIINLNPEVP QALENVVIKA
260 270 280 290 300
TAKDIKNRYT DVEEMMTDVA TSTSLDRRGE EKLVFNKDHD ETKIMPANLI
310 320 330 340 350
NPYDTKPLID KKEDNDSQTD EKAASSEVGN KNKKSKKGLI IGLIILLLVV
360 370 380 390 400
GGATLAWVVS TPTNVKIPNV TNSTLSQAKS KIKDAKLKVG TVHKQQSSTI
410 420 430 440 450
AEGKVIKTDP TSGTTVRSNS SVDIYVSTGN EDIIKMKDFV GEKIDEAMAT
460 470 480 490 500
LLKDYGIDES QVTQTSVPSD SYPAGTIIKQ SPKKGSSFDT KGSEKITFEV
510 520 530 540 550
SSGKQVEVPD YKPNGQYMTY SQYQAALKAA GFTNITLDPQ ATTNQQADGY
560 570 580 590 600
VYSVYPNVGT SVDPTQEIVV TYSVYTAPSS SSTTSESTTT SETSSSTTSS
610 620
TSSSTTSQPS TDNNNSSKES STTSSSS
Length:627
Mass (Da):67,878
Last modified:June 1, 2001 - v1
Checksum:i00B30B68C5C28A81
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005176 Genomic DNA. Translation: AAK05985.1.
PIRiG86860.
RefSeqiNP_268044.1. NC_002662.1.
WP_003130801.1. NC_002662.1.

Genome annotation databases

EnsemblBacteriaiAAK05985; AAK05985; L138452.
GeneIDi1115552.
KEGGilla:L138452.
PATRICi22296232. VBILacLac136773_2021.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005176 Genomic DNA. Translation: AAK05985.1.
PIRiG86860.
RefSeqiNP_268044.1. NC_002662.1.
WP_003130801.1. NC_002662.1.

3D structure databases

ProteinModelPortaliQ9CEF5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272623.L138452.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK05985; AAK05985; L138452.
GeneIDi1115552.
KEGGilla:L138452.
PATRICi22296232. VBILacLac136773_2021.

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000037186.
KOiK08884.
OMAiPVCHALQ.
OrthoDBiEOG6B35XT.

Enzyme and pathway databases

BioCyciLLAC272623:GHSH-1994-MONOMER.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00740. PASTA. 3 hits.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 2 hits.
PROSITEiPS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403."
    Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A.
    Genome Res. 11:731-753(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IL1403.

Entry informationi

Entry nameiPKNB_LACLA
AccessioniPrimary (citable) accession number: Q9CEF5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: June 1, 2001
Last modified: July 22, 2015
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.