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Q9CE35 (ACKA1_LACLA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase 1
EC=2.7.2.1
Alternative name(s):
Acetokinase 1
Gene names
Name:ackA1
Ordered Locus Names:LL2013
ORF Names:L73818
OrganismLactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Taxonomic identifier272623 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Streptococcaceae › Lactococcus

Protein attributes

Sequence length395 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 395395Acetate kinase 1 HAMAP MF_00020
PRO_0000107569

Sequences

Sequence LengthMass (Da)Tools
Q9CE35 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 27D3C29227FA5724

FASTA39543,138
        10         20         30         40         50         60 
MTKTLAVNAG SSSMKWQMYE MPEEKVLAKG LIERIGLKDS IVTVKFGEQK EERVFDIPNH 

        70         80         90        100        110        120 
TEAVEVLLED LKRLKIVEEF TEITGVGHRV VAGGEIFQKS TVVTPEVLQQ VKDLSALAPL 

       130        140        150        160        170        180 
HNPANAAGIE AFLNLLPDAT SVVVFDTAFH TTMPEKAFRY PLPKKYYTDY AVRKYGAHGT 

       190        200        210        220        230        240 
SHMYVSQEAA KLLGKPIEET KIITAHIGNG ASLTAVKGGK SIDTSMGFTP LAGVMMGTRT 

       250        260        270        280        290        300 
GEMDPSVFPY LIENDSELKD AQGVVDMMNK ESGLYGVSGI SSDMRDIIAA KDTDTDAKLA 

       310        320        330        340        350        360 
FEMYVDRIQK FIGQYLAVLN GADALVFTAG IGENSVPVRE AILSGLTWFG IEVDPEKNVF 

       370        380        390 
GVEGEISTPH SRVKVFVIPT DEELVIARDV EALKK

« Hide

References

[1]"The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403."
Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A.
Genome Res. 11:731-753(2001) [PubMed: 11337471] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IL1403.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE005176 Genomic DNA. Translation: AAK06111.1.
PIRE86876.
RefSeqNP_268170.1. NC_002662.1.

3D structure databases

ProteinModelPortalQ9CE35.
SMRQ9CE35. Positions 3-393.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1115689.
GenomeReviewsGene locus LL2013 in contig AE005176_GR.
KEGGlla:L73818.
NMPDRfig|272623.1.peg.2067.
PATRIC22296550. VBILacLac136773_2168.

Phylogenomic databases

HOGENOMHBG285863.
OMALIDMTNE.
ProtClustDBCLSK698067.

Enzyme and pathway databases

BioCycLLAC272623:L73818-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA1_LACLA
AccessionPrimary (citable) accession number: Q9CE35
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: June 1, 2001
Last modified: January 25, 2012
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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