SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9CDL9

- GLNA_LACLA

UniProt

Q9CDL9 - GLNA_LACLA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutamine synthetase

Gene
glnA, LL2200, L0118
Organism
Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

Enzyme regulationi

The activity of this enzyme is controlled by adenylation under conditions of abundant glutamine. The fully adenylated enzyme complex is inactive By similarity.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutamate-ammonia ligase activity Source: UniProtKB-EC

GO - Biological processi

  1. glutamine biosynthetic process Source: InterPro
  2. nitrogen fixation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciLLAC272623:GHSH-2341-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine synthetase (EC:6.3.1.2)
Alternative name(s):
Glutamate--ammonia ligase
Gene namesi
Name:glnA
Ordered Locus Names:LL2200
ORF Names:L0118
OrganismiLactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Taxonomic identifieri272623 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus
ProteomesiUP000002196: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 446446Glutamine synthetasePRO_0000153242Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei375 – 3751O-AMP-tyrosine By similarity

Keywords - PTMi

Phosphoprotein

PTM databases

PhosSiteiP0809339.

Interactioni

Subunit structurei

Oligomer of 12 subunits arranged in the form of two hexagons By similarity.

Protein-protein interaction databases

STRINGi272623.L0118.

Structurei

3D structure databases

ProteinModelPortaliQ9CDL9.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0174.
HOGENOMiHOG000005156.
KOiK01915.
OMAiIEWDMFR.
OrthoDBiEOG6B360N.

Family and domain databases

Gene3Di3.10.20.70. 1 hit.
3.30.590.10. 1 hit.
InterProiIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR004809. Gln_synth_I.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamiPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMiSSF54368. SSF54368. 1 hit.
TIGRFAMsiTIGR00653. GlnA. 1 hit.
PROSITEiPS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9CDL9-1 [UniParc]FASTAAdd to Basket

« Hide

MTITAADIRR DVKEKDIKFL RLMFTDILGT LKNVEVPATD EQLDKLFENK    50
MMFDGSSIEG FVRINESDMY LYPDLDTWIV FPWGDEYGKV AGVICDVYTP 100
EGEPFAGDPR GVLKRNLKSM EKLGFKSFNL GPEPEFFLFK LNENDEPTLE 150
VNDKGGYFDL APTDLAGNTR REIVNVLTDL GFEVEASHHE VAIGQHEIDF 200
KYANALKACD NIQIFKLVVK TIARKHGLHA TFMAKPVHGI NGSGMHCNMS 250
LFTEDGANAF ADPTGDMGLS DVAHSFIAGL LKHAYNFTAI TNPTVNSYKR 300
LVPGYEAPVY VAWAGRNRSP LIRVPASRGL STRVELRAVD PTANPYLALA 350
VLLAAGLDGV EHKLEAPEAI ESNIYVMTEE ERKAHGITDL PSTLHNAVKA 400
LPEDTIVTEA LGEHVLVNFV EAKRIEWASY AQFVSQWEID NYLELY 446
Length:446
Mass (Da):49,693
Last modified:June 1, 2001 - v1
Checksum:iC0A953D5341AD5CF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE005176 Genomic DNA. Translation: AAK06298.1.
PIRiH86899.
RefSeqiNP_268357.1. NC_002662.1.

Genome annotation databases

EnsemblBacteriaiAAK06298; AAK06298; L0118.
GeneIDi1115878.
KEGGilla:L0118.
PATRICi22296956. VBILacLac136773_2362.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE005176 Genomic DNA. Translation: AAK06298.1 .
PIRi H86899.
RefSeqi NP_268357.1. NC_002662.1.

3D structure databases

ProteinModelPortali Q9CDL9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272623.L0118.

PTM databases

PhosSitei P0809339.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK06298 ; AAK06298 ; L0118 .
GeneIDi 1115878.
KEGGi lla:L0118.
PATRICi 22296956. VBILacLac136773_2362.

Phylogenomic databases

eggNOGi COG0174.
HOGENOMi HOG000005156.
KOi K01915.
OMAi IEWDMFR.
OrthoDBi EOG6B360N.

Enzyme and pathway databases

BioCyci LLAC272623:GHSH-2341-MONOMER.

Family and domain databases

Gene3Di 3.10.20.70. 1 hit.
3.30.590.10. 1 hit.
InterProi IPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR004809. Gln_synth_I.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view ]
Pfami PF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view ]
SUPFAMi SSF54368. SSF54368. 1 hit.
TIGRFAMsi TIGR00653. GlnA. 1 hit.
PROSITEi PS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403."
    Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A.
    Genome Res. 11:731-753(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IL1403.

Entry informationi

Entry nameiGLNA_LACLA
AccessioniPrimary (citable) accession number: Q9CDL9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: June 1, 2001
Last modified: September 3, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi