Reviewed, UniProtKB/Swiss-Prot Q9CDA9 (EMBB_MYCLE)

Names and origin

Protein names

Recommended name:
    Probable arabinosyltransferase B
    EC=2.4.2.-

Gene names

Name:	embB
Ordered Locus Names:	ML0104

Organism

Mycobacterium leprae [Complete proteome] [HAMAP]

Taxonomic identifier

1769 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	1083 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan By similarity.
Subcellular location	Cell membrane; Multi-pass membrane protein Probable.
Sequence similarities	Belongs to the emb family.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation
Cellular component	Cell membrane Membrane
Domain	Transmembrane
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	transferase activity, transferring pentosyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1083	1083	Probable arabinosyltransferase B		PRO_0000220567
Regions
	Transmembrane	23 – 45	23	Potential
	Transmembrane	222 – 239	18	Potential
	Transmembrane	252 – 274	23	Potential
	Transmembrane	331 – 350	20	Potential
	Transmembrane	357 – 379	23	Potential
	Transmembrane	421 – 443	23	Potential
	Transmembrane	456 – 478	23	Potential
	Transmembrane	525 – 542	18	Potential
	Transmembrane	555 – 572	18	Potential
	Transmembrane	576 – 598	23	Potential
	Transmembrane	611 – 633	23	Potential
	Transmembrane	648 – 670	23	Potential
	Transmembrane	690 – 712	23	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9CDA9-1 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 391009AF336F0DCF	FASTA	1,083	117,158
	10 20 30 40 50 60 MSVIYRAHRV AIANRTASRN VRVARWVAAI AGLIGFVSSV VTPLLPVVQT TATLNWPQNG 70 80 90 100 110 120 QLNSVTAPLI SLTPVDITAT VPCAVVAALP PSGGVVLGTA PKQGKDANLN ALFIDVNSQR 130 140 150 160 170 180 VDVTDRNVVI LSVPRNQVAG DAGAPGCSSI EVTSTHAGTF ATFVGVTDSA GNPLRGGFPD 190 200 210 220 230 240 PNLRPQIVGV FTDLTGGAPS GLRLSATIDT RFSSTPTTLK RFAMMLAIIT TVGALVALWR 250 260 270 280 290 300 LDQLDGRRMR RLIPARWSMF TLVDVAVIFG FLLWHVIGAN SSDDGYQMQM ARTADHSGYM 310 320 330 340 350 360 ANYFRWFGSP EDPFGWYYNL LALMIHVSDA SMWIRLPDLI CGVACWLLLS REVLPRLGPA 370 380 390 400 410 420 IVGFKPALWA AGLVLLAAWM PFNNGLRPEG QIALGALITY VLIERAITYG RMTPVALATL 430 440 450 460 470 480 TAAFTIGIQP TGLIAVAALL AGGRPMLYIL VRRHRAVGAW PLVAPLLAAG TVVLTVVFAE 490 500 510 520 530 540 QTLSTVLEAT KVRTAIGPAQ AWYTENLRYY YLILPTVDGS LSRRFGFLIT ALCLFTAVLI 550 560 570 580 590 600 TLRRKQIPGV ARGPAWRLIG TILGTMFFLT FAPTKWVHHF GLFAALGAAV AALTTVLVSH 610 620 630 640 650 660 EVLRWSRNRM AFLAALLFVM TLCFATTNGW WYVSSYGVPF NSAMPRIDGI TFSTIFFILF 670 680 690 700 710 720 AIVALYAYYL HFTNTGHGEG RLIRTLTVSF WAPIPFAAGL MTLVFIGSMV AGIVRQYPTY 730 740 750 760 770 780 SNGWANIRAL TGGCGLADDV LVEPDSNAGY MTALPSNYGP LGPLGGVNAI GFTANGVPEH 790 800 810 820 830 840 TVAEAIRITP NQPGTDYDWE APTKLKAPGI NGSVVPLPYG LNPNKVPIAG TYTTGAQQQS 850 860 870 880 890 900 RLTSAWYQLP KPDDRHPLVV VTAAGKITGN SVLHGHTYGQ TVVLEYGDPG PNGGLVPAGR 910 920 930 940 950 960 LVPDDLYGEQ PKAWRNLRFA RSQMPFDAVA VRVVAENLSL TPEDWIAVTP PRVPELRSLQ 970 980 990 1000 1010 1020 EYVGSSQPVL LDWEVGLAFP CQQPMLHANG VTDIPKFRIT PDYSAKKIDT DTWEDGANGG 1030 1040 1050 1060 1070 1080 LLGITDLLLR AHVMSTYLAR DWGRDWGSLR KFDPLVDTHP AQLDLDTATR SGWWSPGKIR IKP

References

[1]

"Massive gene decay in the leprosy bacillus." Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R., Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E., Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K., Duthoy S. , Feltwell T., Fraser A., Hamlin N., Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S., Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R., Barrell B.G. Nature 409:1007-1011(2001) [PubMed: 11234002] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TN.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL583917 Genomic DNA. Translation: CAC29612.1.
PIR	H86921.
RefSeq	NP_301201.1.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GT53. Glycosyltransferase Family 53.
Genome annotation databases
GeneID	908335.
GenomeReviews	Gene locus ML0104 in contig AL450380_GR.
KEGG	mle:ML0104.
NMPDR	fig|272631.1.peg.73.
Organism-specific databases
Leproma	ML0104.
CMR	Search...
Phylogenomic databases
HOGENOM	Q9CDA9.
OMA	Q9CDA9. NGWANIR.
Enzyme and pathway databases
BioCyc	MLEP272631:ML0104-MON.
Family and domain databases
InterPro	IPR007680. Arab_transf. [Graphical view]
Pfam	PF04602. Arabinose_trans. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EMBB_MYCLE

Accession

Primary (citable) accession number: Q9CDA9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2002
Last sequence update:	June 1, 2001
Last modified:	June 16, 2009
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)