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Protein

50S ribosomal protein L25

Gene

rplY

Organism
Mycobacterium leprae (strain TN)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L25UniRule annotation
Alternative name(s):
General stress protein CTCUniRule annotation
Gene namesi
Name:rplYUniRule annotation
Synonyms:ctcUniRule annotation
Ordered Locus Names:ML0245
OrganismiMycobacterium leprae (strain TN)
Taxonomic identifieri272631 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000000806 Componenti: Chromosome

Organism-specific databases

LepromaiML0245.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 21521550S ribosomal protein L25PRO_0000181568Add
BLAST

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.UniRule annotation

Protein-protein interaction databases

STRINGi272631.ML0245.

Structurei

3D structure databases

ProteinModelPortaliQ9CD48.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L25P family. CTC subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG1825. LUCA.
HOGENOMiHOG000214908.
KOiK02897.
OMAiVTCLPKD.
OrthoDBiEOG6SZ1PC.

Family and domain databases

Gene3Di2.170.120.20. 1 hit.
2.40.240.10. 1 hit.
HAMAPiMF_01334. Ribosomal_L25_CTC.
InterProiIPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR029751. Ribosomal_L25.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR020057. Ribosomal_L25_b-dom.
IPR001021. Ribosomal_L25_long.
[Graphical view]
PfamiPF01386. Ribosomal_L25p. 1 hit.
PF14693. Ribosomal_TL5_C. 1 hit.
[Graphical view]
ProDomiPD012503. Ribosomal_L25. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00731. bL25_bact_ctc. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9CD48-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKSTVNKLS VSVRTNTGKG ASRRARRDGK VPAVLYGHGE EPQHLELPAH
60 70 80 90 100
AFSAVLRHVG TNAVLTLEVA GKEQLALTKA IDVHPIRHTI MHADLLVVRS
110 120 130 140 150
GEKIVVEVPV EVEGDAGPDI LVTQETTSIE IEAEALSIPE QLTMSIEGAE
160 170 180 190 200
PGTQFTARQI PLPVGVTLVS DPEMLVVNVV NAPTDAQTKA KYAGEAHEAP
210
EVGTAENKTA ATESE
Length:215
Mass (Da):22,783
Last modified:April 27, 2001 - v1
Checksum:iB5564D05E813B050
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL583917 Genomic DNA. Translation: CAC29753.1.
PIRiE86939.
RefSeqiNP_301304.1. NC_002677.1.
WP_010907628.1. NC_002677.1.

Genome annotation databases

EnsemblBacteriaiCAC29753; CAC29753; CAC29753.
GeneIDi908726.
KEGGimle:ML0245.
PATRICi18050856. VBIMycLep78757_0379.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL583917 Genomic DNA. Translation: CAC29753.1.
PIRiE86939.
RefSeqiNP_301304.1. NC_002677.1.
WP_010907628.1. NC_002677.1.

3D structure databases

ProteinModelPortaliQ9CD48.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272631.ML0245.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC29753; CAC29753; CAC29753.
GeneIDi908726.
KEGGimle:ML0245.
PATRICi18050856. VBIMycLep78757_0379.

Organism-specific databases

LepromaiML0245.

Phylogenomic databases

eggNOGiCOG1825. LUCA.
HOGENOMiHOG000214908.
KOiK02897.
OMAiVTCLPKD.
OrthoDBiEOG6SZ1PC.

Family and domain databases

Gene3Di2.170.120.20. 1 hit.
2.40.240.10. 1 hit.
HAMAPiMF_01334. Ribosomal_L25_CTC.
InterProiIPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR029751. Ribosomal_L25.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR020057. Ribosomal_L25_b-dom.
IPR001021. Ribosomal_L25_long.
[Graphical view]
PfamiPF01386. Ribosomal_L25p. 1 hit.
PF14693. Ribosomal_TL5_C. 1 hit.
[Graphical view]
ProDomiPD012503. Ribosomal_L25. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00731. bL25_bact_ctc. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TN.

Entry informationi

Entry nameiRL25_MYCLE
AccessioniPrimary (citable) accession number: Q9CD48
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: April 27, 2001
Last modified: November 11, 2015
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.