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Reviewed, UniProtKB/Swiss-Prot Q9CCL9 (ADD_MYCLE)

Last modified February 9, 2010. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Adenosine deaminase
    EC=3.5.4.4
Alternative name(s):
    Adenosine aminohydrolase
Gene names
Name: add
Ordered Locus Names: ML0700
ORF Names: L308_C2_206
OrganismMycobacterium leprae [Complete proteome] [HAMAP]
Taxonomic identifier1769 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium

Protein attributes

Sequence length362 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Adenosine + H2O = inosine + NH3. HAMAP MF_00540

Sequence similarities

Belongs to the adenosine and AMP deaminases family.

Ontologies

Keywords
   Biological processNucleotide metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processpurine ribonucleoside monophosphate biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionadenosine deaminase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 362362Adenosine deaminase HAMAP MF_00540
PRO_0000194373

Sites

Active site2081 Potential
Active site2671 Potential
Active site3001 Potential
Active site3011 Potential

Sequences

Sequence LengthMass (Da)Tools
Q9CCL9-1 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: ED0C43B5C92908F5

FASTA36239,637
        10         20         30         40         50         60 
MNTPLHLENI KQAPKALLHD HLDGGLRPAT VLDIAGQVGY DRLPATDVES LETWFRTASH 

        70         80         90        100        110        120 
SGSLERYLEP FSHTVAVMQT PEALHRVAYE CVEDLAADSV VYAEVRFAPE LHIDEGLSFD 

       130        140        150        160        170        180 
EVLASVLAGF ADGERACAAE GNAITVRCLV TAMRHAAMSR EIAELAIRFR DKGVVGFDIA 

       190        200        210        220        230        240 
GAEAGHPPTR HLDAFEYMRS NNARFTIHAG EAFGLPSIHE AIAFCGADRL GHGVRIVDDI 

       250        260        270        280        290        300 
DVDPGGGIRL GPLASILRDK RIPLELCPSS NLQTGAVASI TEHPFDLLAW ARFRVTVNTD 

       310        320        330        340        350        360 
NRLMSDTSMS LEMHRLVEAF GYGWGDLERF TINAMKSAFI PFDQRLAIID EVIKPRFAVL 


VG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00022 Genomic DNA. Translation: AAA17330.1. Different initiation.
AL583919 Genomic DNA. Translation: CAC30209.1.
PIRE86996.
S73031.
RefSeqNP_301559.1.

3D structure databases

SMRQ9CCL9. Positions 12-354.
ModBaseSearch...

Genome annotation databases

GeneID910518.
KEGGmle:ML0700.
NMPDRfig|272631.1.peg.431.

Organism-specific databases

LepromaML0700.
CMRSearch...

Phylogenomic databases

HOGENOMHBG630382.
OMAFLKKLDW.

Enzyme and pathway databases

BioCycMLEP272631:ML0700-MONOMER.
BRENDA3.5.4.4. 808.

Family and domain databases

HAMAPMF_00540. A_deaminase.
[Tree]
InterProIPR001365. A/AMP_deaminase.
IPR006330. A_deaminase.
[Graphical view]
PANTHERPTHR11409. A/AMP_deaminase. 1 hit.
PfamPF00962. A_deaminase. 1 hit.
[Graphical view]
TIGRFAMsTIGR01430. aden_deam. 1 hit.
PROSITEPS00485. A_DEAMINASE. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameADD_MYCLE
AccessionPrimary (citable) accession number: Q9CCL9
Secondary accession number(s): Q49907
Entry history
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: June 1, 2001
Last modified: February 9, 2010
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents