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Q9CCF0 (COX4_MYCLE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable cytochrome c oxidase polypeptide 4

EC=1.9.3.1
Alternative name(s):
Cytochrome aa3 subunit 4
Cytochrome c oxidase polypeptide IV
Gene names
Name:ctaF
Ordered Locus Names:ML0876
OrganismMycobacterium leprae (strain TN) [Complete proteome] [HAMAP]
Taxonomic identifier272631 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium

Protein attributes

Sequence length139 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of cytochrome c oxidase, its function is unknown By similarity.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subunit structure

Associates with subunits I, II and III to form cytochrome c oxidase By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase bacterial subunit CtaF family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 139139Probable cytochrome c oxidase polypeptide 4
PRO_0000220017

Regions

Transmembrane10 – 3021Helical; Potential
Transmembrane36 – 5621Helical; Potential
Transmembrane79 – 9921Helical; Potential
Transmembrane101 – 12121Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q9CCF0 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 0CE348456D833A01

FASTA13914,970
        10         20         30         40         50         60 
MHIEARLFEF VAVFFVIMAV LYGVLTSMFA TGGVDWVGTT ALALTGGLAL IVATFFRFVA 

        70         80         90        100        110        120 
RRLDIRPEDY EGAEISDGAG ELGFFSPHSW WPVLVALSGS VAAVGIALWL PWLIVAGVVF 

       130 
VLASAAGLVF EYYVGPEKH 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL583920 Genomic DNA. Translation: CAC31257.1.
PIRF87018.
RefSeqNP_301662.1. NC_002677.1.

3D structure databases

ProteinModelPortalQ9CCF0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272631.ML0876.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC31257; CAC31257; CAC31257.
GeneID909880.
KEGGmle:ML0876.
PATRIC18053322. VBIMycLep78757_1606.

Organism-specific databases

LepromaML0876.
CMRSearch...

Phylogenomic databases

eggNOGNOG07397.
HOGENOMHOG000237887.
OMAGTYFRFV.
OrthoDBEOG63FW2X.

Family and domain databases

InterProIPR021050. Cyt_c_oxidase_su4_actinobac.
[Graphical view]
PfamPF12270. Cyt_c_ox_IV. 1 hit.
[Graphical view]
PIRSFPIRSF017385. CtaF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCOX4_MYCLE
AccessionPrimary (citable) accession number: Q9CCF0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: June 1, 2001
Last modified: May 14, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families