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Protein

Glutathione S-transferase U11

Gene

GSTU11

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

GO - Biological processi

  • glutathione metabolic process Source: GO_Central
  • toxin catabolic process Source: TAIR

Keywordsi

Molecular functionTransferase
Biological processDetoxification, Stress response

Enzyme and pathway databases

BioCyciARA:AT1G69930-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase U11 (EC:2.5.1.18)
Short name:
AtGSTU11
Alternative name(s):
GST class-tau member 11
Gene namesi
Name:GSTU11
Ordered Locus Names:At1g69930
ORF Names:T17F3.4
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G69930.
TAIRilocus:2196810. AT1G69930.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004135571 – 234Glutathione S-transferase U11Add BLAST234

Proteomic databases

PaxDbiQ9CAS6.

PTM databases

iPTMnetiQ9CAS6.

Expressioni

Inductioni

By fungal elicitor.1 Publication

Gene expression databases

ExpressionAtlasiQ9CAS6. baseline and differential.
GenevisibleiQ9CAS6. AT.

Interactioni

Protein-protein interaction databases

BioGridi28550. 1 interactor.
IntActiQ9CAS6. 1 interactor.
STRINGi3702.AT1G69930.1.

Structurei

3D structure databases

ProteinModelPortaliQ9CAS6.
SMRiQ9CAS6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 90GST N-terminalAdd BLAST80
Domaini96 – 228GST C-terminalAdd BLAST133

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni21 – 22Glutathione bindingBy similarity2
Regioni47 – 48Glutathione bindingBy similarity2
Regioni61 – 62Glutathione bindingBy similarity2
Regioni74 – 75Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Tau family.Curated

Phylogenomic databases

eggNOGiKOG0406. Eukaryota.
ENOG410XSIX. LUCA.
HOGENOMiHOG000125749.
InParanoidiQ9CAS6.
KOiK00799.
OMAiFIHPKNT.
OrthoDBiEOG09360N01.
PhylomeDBiQ9CAS6.

Family and domain databases

InterProiView protein in InterPro
IPR010987. Glutathione-S-Trfase_C-like.
IPR036282. Glutathione-S-Trfase_C_sf.
IPR004045. Glutathione_S-Trfase_N.
IPR036249. Thioredoxin-like_sf.
PfamiView protein in Pfam
PF13417. GST_N_3. 1 hit.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiView protein in PROSITE
PS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9CAS6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLMNRSKND EYVKLLGAWP SPFVLRTRIA LNLKNVAYEY LEEEDTLSSE
60 70 80 90 100
SVLNYNPVHK QIPILIHGNK PIRESLNIVM YVDETWLSGP PILPSDPFDR
110 120 130 140 150
AVARFWDVYI DEHCFTSING VAVAKGEENI NAAIAKLEQC MALLEETFQE
160 170 180 190 200
CSKGRGFFGG ENIGFIDIGF GSMLGPLTVL EKFTGVKFIH PENTPGLFHW
210 220 230
ADRFYAHEAV KPVMPDIEKL VQFARLKFNT SIFK
Length:234
Mass (Da):26,516
Last modified:June 1, 2001 - v1
Checksum:i5B2686289DB65206
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010675 Genomic DNA. Translation: AAG52568.1.
CP002684 Genomic DNA. Translation: AEE34999.1.
AK119143 mRNA. Translation: BAC43713.1.
BT006220 mRNA. Translation: AAP12869.1.
PIRiG96721.
RefSeqiNP_177151.1. NM_105661.5.
UniGeneiAt.20559.

Genome annotation databases

EnsemblPlantsiAT1G69930.1; AT1G69930.1; AT1G69930.
GeneIDi843329.
GrameneiAT1G69930.1; AT1G69930.1; AT1G69930.
KEGGiath:AT1G69930.

Similar proteinsi

Entry informationi

Entry nameiGSTUB_ARATH
AccessioniPrimary (citable) accession number: Q9CAS6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: June 1, 2001
Last modified: October 25, 2017
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families