Q9CA71 (FUT3_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Fucosyltransferase 3
Short name=AtFUT3
EC=2.4.1.-

Gene names

Name:	FUT3
Ordered Locus Names:	At1g74420
ORF Names:	F1M20.10

Organism

Arabidopsis thaliana (Mouse-ear cress)

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	521 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	May be involved in cell wall biosynthesis. May act as a fucosyltransferase.
Pathway	Protein modification; protein glycosylation.
Subcellular location	Golgi apparatus › Golgi stack membrane; Single-pass type II membrane protein By similarity. Note: Membrane-bound form in trans cisternae of Golgi By similarity.
Tissue specificity	Expressed in roots, stems, leaves, flowers, siliques and seedlings.
Sequence similarities	Belongs to the glycosyltransferase 37 family.
Sequence caution	The sequence AAG52352.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence AAL50622.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation
Cellular component	Golgi apparatus Membrane
Coding sequence diversity	Alternative splicing
Domain	Signal-anchor Transmembrane Transmembrane helix
Molecular function	Glycosyltransferase Transferase
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cell wall biogenesis Inferred from electronic annotation. Source: InterPro cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	Golgi cisterna membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	galactoside 2-alpha-L-fucosyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 1 isoform produced by alternative splicing. [Select]

Note: A number of isoforms are produced. According to EST sequences.

Isoform 1 (identifier: Q9CA71-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 521	521	Fucosyltransferase 3		PRO_0000193912
Regions
	Topological domain	1 – 39	39	Cytoplasmic Potential
	Transmembrane	40 – 60	21	Helical; Signal-anchor for type II membrane protein; Potential
	Topological domain	61 – 521	461	Lumenal Potential
	Compositional bias	404 – 407	4	Poly-Ser
Amino acid modifications
	Glycosylation	152	1	N-linked (GlcNAc...) Potential
	Glycosylation	222	1	N-linked (GlcNAc...) Potential
	Glycosylation	493	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified May 29, 2007. Version 3. Checksum: D2AB9A0FD84CAFFC	FASTA	521	58,989
	10 20 30 40 50 60 MKRGKKNSDA GDRLTNSDTR TGSSELNAMM KPSLSSMKTM GLLLAVLMVA SVMFSLSVVL 70 80 90 100 110 120 RDPPSDDVIE TEAASRVLQS RLHQDGGLSE KKAQLGNINL VPSFDKESCL SRYEASLYRK 130 140 150 160 170 180 ESPFKQSSYL DYRLQRYEDL HRRCGPFTRS YNLTLDKLKS GDRSDGEVSG CRYVIWLNSN 190 200 210 220 230 240 GDLGNRMLSL ASAFLYALLT NRFLLVELGV DMADLFCEPF PNTTWFLPPE FPLNSHFNEQ 250 260 270 280 290 300 SLLRNSGNPM VAYRHVVRDS SDQQKLFFCE DSQVLLEETP WLILKADSFF LPSLFSVSSF 310 320 330 340 350 360 KQELQMLFPE KDTAFHFLSQ YLFHPTNVVW GLITRYYNAY LAKADQRIGI YIGVSESGNE 370 380 390 400 410 420 QFQHLIDQIL ACGTRHKLLP EVDKQRNLPS SQVLNRKSKA VFISSSSPGY FKSIRDVYWE 430 440 450 460 470 480 NPTVMGEIIS VHKPSYKDYQ KTPRNMESKR AWAEIYLLSC SDALVVTGLW SSLVEVAHGL 490 500 510 520 GGLKPWVLNK AENGTAHEPY CVKARSIEPC SQATLFHGCK D

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed: 11130712] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs." Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K. Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[4]	"Characterization of a family of Arabidopsis genes related to xyloglucan fucosyltransferase1." Sarria R., Wagner T.A., O'Neill M.A., Faik A., Wilkerson C.G., Keegstra K., Raikhel N.V. Plant Physiol. 127:1595-1606(2001) [PubMed: 11743104] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 9-521.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC011765 Genomic DNA. Translation: AAG52352.1. Sequence problems. CP002684 Genomic DNA. Translation: AEE35589.1. AK175419 mRNA. Translation: BAD43182.1. AK176710 mRNA. Translation: BAD44473.1. AF417473 mRNA. Translation: AAL50622.1. Different initiation.
IPI	IPI00522933.
RefSeq	NP_177582.3. NM_106102.4.
UniGene	At.20400. At.28630.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GT37. Glycosyltransferase Family 37.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT1G74420.1; AT1G74420.1; AT1G74420.
GeneID	843783.
GenomeReviews	Gene locus AT1G74420 in contig CT485782_GR.
KEGG	ath:AT1G74420.
NMPDR	fig|3702.1.peg.6954.
Organism-specific databases
TAIR	At1g74420.
Phylogenomic databases
GeneTree	EPGT00050000010289.
HOGENOM	HBG319216.
InParanoid	Q9CA71.
PhylomeDB	Q9CA71.
ProtClustDB	CLSN2681300.
Gene expression databases
Genevestigator	Q9CA71.
Family and domain databases
InterPro	IPR004938. XG_FTase. [Graphical view]
KO	K13681.
Pfam	PF03254. XG_FTase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FUT3_ARATH

Accession

Primary (citable) accession number: Q9CA71
Secondary accession number(s): Q67XV8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 5, 2002
Last sequence update:	May 29, 2007
Last modified:	December 14, 2011
This is version 63 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program