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Protein

Auxin transporter-like protein 3

Gene

LAX3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Carrier protein involved in proton-driven auxin influx. Mediates the formation of auxin gradient from developing leaves (site of auxin biosynthesis) to tips by contributing to the loading of auxin in vascular tissues and facilitating acropetal (base to tip) auxin transport within inner tissues of the root apex, and basipetal (tip to base) auxin transport within outer tissues of the root apex (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

  • amino acid transmembrane transport Source: GO_Central
  • auxin-activated signaling pathway Source: UniProtKB-KW
  • auxin polar transport Source: TAIR
  • lateral root formation Source: TAIR
  • response to auxin Source: TAIR
  • root cap development Source: TAIR

Keywordsi

Biological processAmino-acid transport, Auxin signaling pathway, Symport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Auxin transporter-like protein 3
Alternative name(s):
AUX1-like protein 3
Gene namesi
Name:LAX3
Ordered Locus Names:At1g77690
ORF Names:T32E8.2
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G77690
TAIRilocus:2203226 AT1G77690

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 57CytoplasmicSequence analysisAdd BLAST57
Transmembranei58 – 75HelicalSequence analysisAdd BLAST18
Topological domaini76 – 77ExtracellularSequence analysis2
Transmembranei78 – 98HelicalSequence analysisAdd BLAST21
Topological domaini99 – 134CytoplasmicSequence analysisAdd BLAST36
Transmembranei135 – 155HelicalSequence analysisAdd BLAST21
Topological domaini156 – 170ExtracellularSequence analysisAdd BLAST15
Transmembranei171 – 191HelicalSequence analysisAdd BLAST21
Topological domaini192CytoplasmicSequence analysis1
Transmembranei193 – 213HelicalSequence analysisAdd BLAST21
Topological domaini214 – 230ExtracellularSequence analysisAdd BLAST17
Transmembranei231 – 251HelicalSequence analysisAdd BLAST21
Topological domaini252 – 264CytoplasmicSequence analysisAdd BLAST13
Transmembranei265 – 285HelicalSequence analysisAdd BLAST21
Topological domaini286 – 312ExtracellularSequence analysisAdd BLAST27
Transmembranei313 – 333HelicalSequence analysisAdd BLAST21
Topological domaini334 – 354CytoplasmicSequence analysisAdd BLAST21
Transmembranei355 – 375HelicalSequence analysisAdd BLAST21
Topological domaini376ExtracellularSequence analysis1
Transmembranei377 – 397HelicalSequence analysisAdd BLAST21
Topological domaini398 – 426CytoplasmicSequence analysisAdd BLAST29
Transmembranei427 – 447HelicalSequence analysisAdd BLAST21
Topological domaini448 – 470ExtracellularSequence analysisAdd BLAST23

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000938441 – 470Auxin transporter-like protein 3Add BLAST470

Proteomic databases

PaxDbiQ9CA25

Expressioni

Gene expression databases

ExpressionAtlasiQ9CA25 baseline and differential
GenevisibleiQ9CA25 AT

Interactioni

Protein-protein interaction databases

BioGridi29324, 6 interactors
IntActiQ9CA25, 3 interactors
STRINGi3702.AT1G77690.1

Structurei

3D structure databases

ProteinModelPortaliQ9CA25
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1303 Eukaryota
COG0814 LUCA
HOGENOMiHOG000238482
InParanoidiQ9CA25
KOiK13946
OMAiPSFLGGW
OrthoDBiEOG093606UF
PhylomeDBiQ9CA25

Family and domain databases

InterProiView protein in InterPro
IPR013057 AA_transpt_TM
PfamiView protein in Pfam
PF01490 Aa_trans, 1 hit

Sequencei

Sequence statusi: Complete.

Q9CA25-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAEKIETVV AGNYLEMERE EENISGNKKS STKTKLSNFF WHGGSVYDAW
60 70 80 90 100
FSCASNQVAQ VLLTLPYSFS QLGMMSGILF QLFYGLMGSW TAYLISVLYV
110 120 130 140 150
EYRTRKEREK FDFRNHVIQW FEVLDGLLGK HWRNLGLIFN CTFLLFGSVI
160 170 180 190 200
QLIACASNIY YINDKLDKRT WTYIFGACCA TTVFIPSFHN YRIWSFLGLA
210 220 230 240 250
MTTYTSWYLT IASLLHGQAE DVKHSGPTTM VLYFTGATNI LYTFGGHAVT
260 270 280 290 300
VEIMHAMWKP QKFKAIYLLA TIYVLTLTLP SASAVYWAFG DKLLTHSNAL
310 320 330 340 350
SLLPKTGFRD TAVILMLIHQ FITFGFASTP LYFVWEKLIG VHETKSMFKR
360 370 380 390 400
AMARLPVVVP IWFLAIIFPF FGPINSAVGS LLVSFTVYII PALAHMLTFA
410 420 430 440 450
PAPSRENAVE RPPRVVGGWM GTYCINIFVV VWVFVVGFGF GGWASMVNFV
460 470
RQIDTFGLFT KCYQCPPHKP
Length:470
Mass (Da):53,305
Last modified:June 1, 2001 - v1
Checksum:iB6A50B7900DA7130
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY127575 Genomic DNA Translation: AAN02284.1
AC012193 Genomic DNA Translation: AAG51630.1
CP002684 Genomic DNA Translation: AEE36010.1
AY054266 mRNA Translation: AAL06925.1
BT008300 mRNA Translation: AAP37659.1
PIRiF96806
RefSeqiNP_177892.1, NM_106418.4
UniGeneiAt.17772

Genome annotation databases

EnsemblPlantsiAT1G77690.1; AT1G77690.1; AT1G77690
GeneIDi844105
GrameneiAT1G77690.1; AT1G77690.1; AT1G77690
KEGGiath:AT1G77690

Similar proteinsi

Entry informationi

Entry nameiLAX3_ARATH
AccessioniPrimary (citable) accession number: Q9CA25
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: June 1, 2001
Last modified: May 23, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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