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Protein

Probable histone chaperone ASF1A

Gene

ASF1A

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly (By similarity). While encoded by a region of the Arabidopsis thaliana genome that is homologous to the Brassica S-locus for self incompatibility, this protein may not play the same role in Arabidopsis thaliana.By similarity

GO - Biological processi

  • cell division Source: TAIR
  • chromatin assembly or disassembly Source: InterPro
  • double-strand break repair via homologous recombination Source: TAIR
  • mitotic cell size control checkpoint Source: TAIR
  • regulation of cell size Source: TAIR
  • regulation of transcription, DNA-templated Source: UniProtKB-KW
  • transcription, DNA-templated Source: UniProtKB-KW
  • trichome branching Source: TAIR

Keywordsi

Molecular functionChaperone, Chromatin regulator
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Probable histone chaperone ASF1A
Alternative name(s):
Anti-silencing function protein 1-like protein a
Short name:
Anti-silencing function 1a protein
S-locus protein 7
Short name:
AtSP7
Silencing group A protein 2
Gene namesi
Name:ASF1A
Synonyms:SGA2, SP7
Ordered Locus Names:At1g66740
ORF Names:F4N21.13
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G66740
TAIRilocus:2033359 AT1G66740

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002707971 – 196Probable histone chaperone ASF1AAdd BLAST196

Proteomic databases

PaxDbiQ9C9M6

Expressioni

Tissue specificityi

Expressed in leaves and flower buds.1 Publication

Gene expression databases

ExpressionAtlasiQ9C9M6 baseline and differential
GenevisibleiQ9C9M6 AT

Interactioni

Subunit structurei

Interacts with histone H3 and histone H4 (By similarity). Component of the HIRA complex made of UBN1, UBN2, ASF1A, CABIN1 and HIRA. Interacts with HIRA (PubMed:25086063).By similarity1 Publication

Protein-protein interaction databases

BioGridi28213, 1 interactor
STRINGi3702.AT1G66740.1

Structurei

3D structure databases

ProteinModelPortaliQ9C9M6
SMRiQ9C9M6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ASF1 family.Curated

Phylogenomic databases

eggNOGiKOG3265 Eukaryota
COG5137 LUCA
HOGENOMiHOG000197425
InParanoidiQ9C9M6
KOiK10753
OMAiISYECLN
OrthoDBiEOG09360MXQ
PhylomeDBiQ9C9M6

Family and domain databases

Gene3Di2.60.40.1490, 1 hit
InterProiView protein in InterPro
IPR006818 ASF1-like
IPR036747 ASF1-like_sf
PANTHERiPTHR12040 PTHR12040, 1 hit
PfamiView protein in Pfam
PF04729 ASF1_hist_chap, 1 hit
SUPFAMiSSF101546 SSF101546, 1 hit

Sequencei

Sequence statusi: Complete.

Q9C9M6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAIKITNVA VLHNPAPFVS PFQFEISYEC LNSLKDDLEW KLIYVGSAED
60 70 80 90 100
ETYDQLLESV LVGPVNVGNY RFVFQADPPD PSKIQEEDII GVTVLLLTCS
110 120 130 140 150
YMGQEFLRVG YYVNNDYEDE QLKEEPPTKV LIDKVQRNIL SDKPRVTKFP
160 170 180 190
IDFHPEEEQT AATAAPPEQS DEQQPNVNGE AQVLPDQSVE PKPEES
Length:196
Mass (Da):22,133
Last modified:June 1, 2001 - v1
Checksum:i259D9842EA77F115
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB078339 mRNA Translation: BAC54103.1
AC013288 Genomic DNA Translation: AAG60078.1
CP002684 Genomic DNA Translation: AEE34550.1
AY096540 mRNA Translation: AAM20190.1
AY065298 mRNA Translation: AAL38774.1
RefSeqiNP_176846.1, NM_105344.4
UniGeneiAt.28464

Genome annotation databases

EnsemblPlantsiAT1G66740.1; AT1G66740.1; AT1G66740
GeneIDi842992
GrameneiAT1G66740.1; AT1G66740.1; AT1G66740
KEGGiath:AT1G66740

Similar proteinsi

Entry informationi

Entry nameiASF1A_ARATH
AccessioniPrimary (citable) accession number: Q9C9M6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: June 1, 2001
Last modified: April 25, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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