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Protein

Cyclin-A2-4

Gene

CYCA2-4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • cell cycle Source: UniProtKB-KW
  • cell division Source: UniProtKB-KW
  • cell proliferation Source: TAIR
  • stomatal complex development Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Cyclin

Keywords - Biological processi

Cell cycle, Cell division

Enzyme and pathway databases

ReactomeiR-ATH-113510. E2F mediated regulation of DNA replication.
R-ATH-1538133. G0 and Early G1.
R-ATH-174184. Cdc20:Phospho-APC/C mediated degradation of Cyclin A.
R-ATH-5689880. Ub-specific processing proteases.
R-ATH-68911. G2 Phase.
R-ATH-68949. Orc1 removal from chromatin.
R-ATH-69205. G1/S-Specific Transcription.
R-ATH-69273. Cyclin A/B1 associated events during G2/M transition.
R-ATH-69656. Cyclin A:Cdk2-associated events at S phase entry.

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-A2-4
Alternative name(s):
G2/mitotic-specific cyclin-A2-4
Short name:
CycA2;4
Gene namesi
Name:CYCA2-4
Ordered Locus Names:At1g80370
ORF Names:F5I6.12
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G80370.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002869961 – 461Cyclin-A2-4Add BLAST461

Proteomic databases

PaxDbiQ9C968.

Expressioni

Gene expression databases

GenevisibleiQ9C968. AT.

Interactioni

Protein-protein interaction databases

BioGridi29595. 9 interactors.
STRINGi3702.AT1G80370.1.

Structurei

3D structure databases

ProteinModelPortaliQ9C968.
SMRiQ9C968.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cyclin family. Cyclin AB subfamily.Curated

Phylogenomic databases

eggNOGiKOG0654. Eukaryota.
COG5024. LUCA.
HOGENOMiHOG000167672.
InParanoidiQ9C968.
KOiK06627.
OMAiTEWNRES.
OrthoDBiEOG09360C5F.
PhylomeDBiQ9C968.

Family and domain databases

Gene3Di1.10.472.10. 2 hits.
InterProiIPR013763. Cyclin-like.
IPR004367. Cyclin_C-dom.
IPR006671. Cyclin_N.
[Graphical view]
PfamiPF02984. Cyclin_C. 1 hit.
PF00134. Cyclin_N. 1 hit.
[Graphical view]
SMARTiSM00385. CYCLIN. 2 hits.
SM01332. Cyclin_C. 1 hit.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 2 hits.

Sequencei

Sequence statusi: Complete.

Q9C968-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKENAVSGN SIPIHGRPVT RALASALRAS SKLITSSEVA ATTQNQGRVL
60 70 80 90 100
RAKSKRTALD EKKANAPKKR AVLKDITNVT CENSYTSCFS VAVENIKQIK
110 120 130 140 150
KGRQSSSSSK VASSSATSQV TDAKVEVVSN SAGASLSVFT DTSLGTNETS
160 170 180 190 200
YSIIAKPSSR SPPRPFGTVE RSCGGASSPK FVDIDSDDKD PLLCSLYAPD
210 220 230 240 250
IYYNLRVAEL KRRPFPDFME KTQRDVTETM RGILVDWLVE VSEEYTLVPD
260 270 280 290 300
TLYLTVYLID WFLHGNYVER QRLQLLGITC MLIASKYEEI HAPRIEEFCF
310 320 330 340 350
ITDNTYTRDQ VLEMESQVLK HFSFQIYTPT SKTFLRRFLR AAQVSFPNQS
360 370 380 390 400
LEMEFLANYL TELTLMDYPF LKFLPSIIAA SAVFLAKWTL NQSSHPWNPT
410 420 430 440 450
LEHYTTYKAS DLKASVHALQ DLQLNTKGCS LNSIRMKYRQ DKFKSVAVFS
460
SGELPDKLFI S
Length:461
Mass (Da):51,637
Last modified:June 1, 2001 - v1
Checksum:i7282354BBF7BA241
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018848 Genomic DNA. Translation: AAG52439.1.
CP002684 Genomic DNA. Translation: AEE36392.1.
PIRiD96835.
RefSeqiNP_178153.1. NM_106686.3.
UniGeneiAt.33911.

Genome annotation databases

EnsemblPlantsiAT1G80370.1; AT1G80370.1; AT1G80370.
GeneIDi844377.
GrameneiAT1G80370.1; AT1G80370.1; AT1G80370.
KEGGiath:AT1G80370.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018848 Genomic DNA. Translation: AAG52439.1.
CP002684 Genomic DNA. Translation: AEE36392.1.
PIRiD96835.
RefSeqiNP_178153.1. NM_106686.3.
UniGeneiAt.33911.

3D structure databases

ProteinModelPortaliQ9C968.
SMRiQ9C968.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi29595. 9 interactors.
STRINGi3702.AT1G80370.1.

Proteomic databases

PaxDbiQ9C968.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G80370.1; AT1G80370.1; AT1G80370.
GeneIDi844377.
GrameneiAT1G80370.1; AT1G80370.1; AT1G80370.
KEGGiath:AT1G80370.

Organism-specific databases

TAIRiAT1G80370.

Phylogenomic databases

eggNOGiKOG0654. Eukaryota.
COG5024. LUCA.
HOGENOMiHOG000167672.
InParanoidiQ9C968.
KOiK06627.
OMAiTEWNRES.
OrthoDBiEOG09360C5F.
PhylomeDBiQ9C968.

Enzyme and pathway databases

ReactomeiR-ATH-113510. E2F mediated regulation of DNA replication.
R-ATH-1538133. G0 and Early G1.
R-ATH-174184. Cdc20:Phospho-APC/C mediated degradation of Cyclin A.
R-ATH-5689880. Ub-specific processing proteases.
R-ATH-68911. G2 Phase.
R-ATH-68949. Orc1 removal from chromatin.
R-ATH-69205. G1/S-Specific Transcription.
R-ATH-69273. Cyclin A/B1 associated events during G2/M transition.
R-ATH-69656. Cyclin A:Cdk2-associated events at S phase entry.

Miscellaneous databases

PROiQ9C968.

Gene expression databases

GenevisibleiQ9C968. AT.

Family and domain databases

Gene3Di1.10.472.10. 2 hits.
InterProiIPR013763. Cyclin-like.
IPR004367. Cyclin_C-dom.
IPR006671. Cyclin_N.
[Graphical view]
PfamiPF02984. Cyclin_C. 1 hit.
PF00134. Cyclin_N. 1 hit.
[Graphical view]
SMARTiSM00385. CYCLIN. 2 hits.
SM01332. Cyclin_C. 1 hit.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiCCA24_ARATH
AccessioniPrimary (citable) accession number: Q9C968
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: June 1, 2001
Last modified: November 30, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.