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Protein

Glutathione S-transferase U28

Gene

GSTU28

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

GO - Biological processi

  • glutathione metabolic process Source: GO_Central
  • response to cadmium ion Source: TAIR
  • toxin catabolic process Source: TAIR

Keywordsi

Molecular functionTransferase
Biological processDetoxification

Enzyme and pathway databases

BioCyciARA:AT1G53680-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase U28 (EC:2.5.1.18)
Short name:
AtGSTU28
Alternative name(s):
GST class-tau member 28
Gene namesi
Name:GSTU28
Ordered Locus Names:At1g53680
ORF Names:F22G10.22
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G53680
TAIRilocus:2024857 AT1G53680

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004135731 – 224Glutathione S-transferase U28Add BLAST224

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei154PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9C8M3

Expressioni

Gene expression databases

ExpressionAtlasiQ9C8M3 baseline and differential
GenevisibleiQ9C8M3 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G53680.1

Structurei

3D structure databases

ProteinModelPortaliQ9C8M3
SMRiQ9C8M3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 85GST N-terminalAdd BLAST80
Domaini91 – 217GST C-terminalAdd BLAST127

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni16 – 17Glutathione bindingBy similarity2
Regioni42 – 43Glutathione bindingBy similarity2
Regioni56 – 57Glutathione bindingBy similarity2
Regioni69 – 70Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Tau family.Curated

Phylogenomic databases

eggNOGiKOG0406 Eukaryota
ENOG410XSIX LUCA
HOGENOMiHOG000125749
InParanoidiQ9C8M3
KOiK00799
OMAiVDITLVP
OrthoDBiEOG09360MNS
PhylomeDBiQ9C8M3

Family and domain databases

InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF02798 GST_N, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q9C8M3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKENSKVVV LDFWASPYAM RTKVALREKG VEFEVQEEDL WNKSELLLKS
60 70 80 90 100
NPVHKKVPVL IHNNTPISES LIQVQYIDET WTDAASFLPS DPQSRATARF
110 120 130 140 150
WADYADKTIS FEGGRKIWGN KKGEEQEKGK KEFLESLKVL EAELGDKSYF
160 170 180 190 200
GGETFGYVDI TLVPFYSWFY ALEKCGDFSV EAECPKIVAW GKRCVERNSV
210 220
AATLPESEKV YQQVLKLRQI FGVE
Length:224
Mass (Da):25,591
Last modified:June 1, 2001 - v1
Checksum:i1EC8B43B38573E5D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC024260 Genomic DNA Translation: AAG51968.1
CP002684 Genomic DNA Translation: AEE32981.1
PIRiA96577
RefSeqiNP_175772.1, NM_104246.2

Genome annotation databases

EnsemblPlantsiAT1G53680.1; AT1G53680.1; AT1G53680
GeneIDi841805
GrameneiAT1G53680.1; AT1G53680.1; AT1G53680
KEGGiath:AT1G53680

Similar proteinsi

Entry informationi

Entry nameiGSTUS_ARATH
AccessioniPrimary (citable) accession number: Q9C8M3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: June 1, 2001
Last modified: April 25, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health