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Protein

C-type lectin receptor-like tyrosine-protein kinase At1g52310

Gene

At1g52310

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei296ATPPROSITE-ProRule annotation1
Active sitei394Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi274 – 282ATPPROSITE-ProRule annotation9

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Receptor, Transferase, Tyrosine-protein kinase
LigandATP-binding, Lectin, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
C-type lectin receptor-like tyrosine-protein kinase At1g52310 (EC:2.7.10.1)
Gene namesi
Ordered Locus Names:At1g52310
ORF Names:F19K6.8
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G52310.
TAIRilocus:2018189. AT1G52310.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini28 – 201ExtracellularSequence analysisAdd BLAST174
Transmembranei202 – 222HelicalSequence analysisAdd BLAST21
Topological domaini223 – 552CytoplasmicSequence analysisAdd BLAST330

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_000040332728 – 552C-type lectin receptor-like tyrosine-protein kinase At1g52310Add BLAST525

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi37N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi59N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi69N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi80 ↔ 187PROSITE-ProRule annotation
Glycosylationi106N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi118N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi137N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi154N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi164 ↔ 179PROSITE-ProRule annotation
Glycosylationi169N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi180N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ9C823.

PTM databases

iPTMnetiQ9C823.

Expressioni

Gene expression databases

GenevisibleiQ9C823. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G52310.1.

Structurei

3D structure databases

ProteinModelPortaliQ9C823.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini59 – 188C-type lectinPROSITE-ProRule annotationAdd BLAST130
Domaini268 – 546Protein kinasePROSITE-ProRule annotationAdd BLAST279

Sequence similaritiesi

Belongs to the protein kinase superfamily. Tyr protein kinase family.PROSITE-ProRule annotation

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1187. Eukaryota.
COG0515. LUCA.
HOGENOMiHOG000237405.
InParanoidiQ9C823.
OMAiTLAVVIW.
OrthoDBiEOG093606CH.
PhylomeDBiQ9C823.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR001304. C-type_lectin-like.
IPR016186. C-type_lectin-like/link.
IPR016187. CTDL_fold.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
IPR020635. Tyr_kinase_cat_dom.
PfamiView protein in Pfam
PF00059. Lectin_C. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
SMARTiView protein in SMART
SM00034. CLECT. 1 hit.
SM00220. S_TKc. 1 hit.
SM00219. TyrKc. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
SSF56436. SSF56436. 1 hit.
PROSITEiView protein in PROSITE
PS50041. C_TYPE_LECTIN_2. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9C823-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELKWVSCRK QSLFLISCLA LLCLASLDTI SCESTQNATD FKKRSQTVSC
60 70 80 90 100
PPDWIIGPNQ TKCYAYFKNS TSWEKSEMFC RTYGGHLASL ASSKELSFVQ
110 120 130 140 150
KLCNGNVSSC WIGGRSMNSS TSGFRWSWSD PKTPQWNQSM FPKVPIRTRC
160 170 180 190 200
GNGNGSSSCR ANICIAVTNG SSSIFGERCN ASHAFVCAVD SDIKCRNCHK
210 220 230 240 250
YLVILAVVSG LILFTTFAII LWLLVYKRSK KRRKSRKVSN PASSSSVVPP
260 270 280 290 300
SWKIFTSEEL RSMTKNFSEA NRLAGDAKTG GTYSGGLSDG TKVAVKRLKR
310 320 330 340 350
SSFQRKKEFY SEIRRAAKLY HPNVVAIKGC CYDHGERFIV YEFIASGPLD
360 370 380 390 400
RWLHHVPRGG RSLDWNMRLN IATTLAQGIA FLHDKVKPQV VHRDIRASNV
410 420 430 440 450
LLDEEFGAHL MGVGLSKFVP WEVMQERTVM AGGTYGYLAP EYVYRNELTT
460 470 480 490 500
KSDVYSFGVL LLEIVSGRRP TQAVNSSVGW QSIFEWATPL VQANRWLEIL
510 520 530 540 550
DPVITCGLPE ACVVQKVVDL VYSCTQNVPS MRPRMSHVVH QLQQLVQPLE

VK
Length:552
Mass (Da):61,821
Last modified:June 1, 2001 - v1
Checksum:iC901EB512CCFE4F0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC037424 Genomic DNA. Translation: AAG51547.1.
CP002684 Genomic DNA. Translation: AEE32780.1.
AY062751 mRNA. Translation: AAL32829.1.
BT008903 mRNA. Translation: AAP68342.1.
AK220938 mRNA. Translation: BAD94441.1.
PIRiC96563.
RefSeqiNP_175641.1. NM_104110.3.
UniGeneiAt.27244.

Genome annotation databases

EnsemblPlantsiAT1G52310.1; AT1G52310.1; AT1G52310.
GeneIDi841661.
GrameneiAT1G52310.1; AT1G52310.1; AT1G52310.
KEGGiath:AT1G52310.

Similar proteinsi

Entry informationi

Entry nameiY1523_ARATH
AccessioniPrimary (citable) accession number: Q9C823
Secondary accession number(s): Q56ZM6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: June 1, 2001
Last modified: May 10, 2017
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families