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Protein

U-box domain-containing protein 17

Gene

PUB17

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Functions as an E3 ubiquitin ligase.1 Publication

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Molecular functioni

  • ligase activity Source: UniProtKB-KW
  • ubiquitin-protein transferase activity Source: TAIR

GO - Biological processi

  • defense response, incompatible interaction Source: TAIR
  • protein ubiquitination Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Ubl conjugation pathway

Enzyme and pathway databases

BRENDAi2.3.2.B10. 399.
UniPathwayiUPA00143.

Names & Taxonomyi

Protein namesi
Recommended name:
U-box domain-containing protein 17 (EC:6.3.2.-)
Alternative name(s):
Plant U-box protein 17
Gene namesi
Name:PUB17
Ordered Locus Names:At1g29340
ORF Names:F15D2.34
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G29340.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 729729U-box domain-containing protein 17PRO_0000322161Add
BLAST

Proteomic databases

PaxDbiQ9C7R6.
PRIDEiQ9C7R6.

Expressioni

Gene expression databases

GenevisibleiQ9C7R6. AT.

Interactioni

Protein-protein interaction databases

IntActiQ9C7R6. 1 interaction.
STRINGi3702.AT1G29340.1.

Structurei

3D structure databases

ProteinModelPortaliQ9C7R6.
SMRiQ9C7R6. Positions 306-377, 392-684.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini304 – 37875U-boxAdd
BLAST
Repeati438 – 47740ARM 1Add
BLAST
Repeati479 – 52042ARM 2Add
BLAST
Repeati523 – 56240ARM 3Add
BLAST
Repeati564 – 60138ARM 4Add
BLAST

Sequence similaritiesi

Contains 4 ARM repeats.PROSITE-ProRule annotation
Contains 1 U-box domain.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG410ITMB. Eukaryota.
ENOG410YC2C. LUCA.
HOGENOMiHOG000238412.
InParanoidiQ9C7R6.
OMAiENRAYIA.
PhylomeDBiQ9C7R6.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
3.30.40.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
IPR003613. Ubox_domain.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF00514. Arm. 1 hit.
PF04564. U-box. 1 hit.
[Graphical view]
SMARTiSM00185. ARM. 5 hits.
SM00504. Ubox. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50176. ARM_REPEAT. 1 hit.
PS51698. U_BOX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9C7R6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASAAIFSSL RRRRSPSLEA FLAPVDLSGV ALVQTLASIS SEVVSCFTSV
60 70 80 90 100
RFSFQRKNAR SLIRKIEIFV VLFEFLVDSN WGSTTTRTRA RRRSKSSVSE
110 120 130 140 150
STALLCLKEL YLLLYRSKIL VDYCAQSSKL WLLLQNPSIS GYFHDLNQEI
160 170 180 190 200
STLLDVLPVN DLGLSDDIRE QIELLQRQSR KARLYIDKND ESLRESFYSF
210 220 230 240 250
LDGFENGKIP SSVDLRMFFV EKLGIRDSKS CRSEIEFLEE QIVNHDGDLE
260 270 280 290 300
PTGSVINGFV AITRYCRFLL FGFEEDGMEW WIENNPKKPR KGFVAQEIGD
310 320 330 340 350
TFITVPKDFV CPISLDLMTD PVIISTGQTY DRNSIARWIE EGHCTCPKTG
360 370 380 390 400
QMLMDSRIVP NRALKNLIVQ WCTASGISYE SEFTDSPNES FASALPTKAA
410 420 430 440 450
VEANKATVSI LIKYLADGSQ AAQTVAAREI RLLAKTGKEN RAYIAEAGAI
460 470 480 490 500
PHLCRLLTSE NAIAQENSVT AMLNLSIYEK NKSRIMEEGD CLESIVSVLV
510 520 530 540 550
SGLTVEAQEN AAATLFSLSA VHEYKKRIAI VDQCVEALAL LLQNGTPRGK
560 570 580 590 600
KDAVTALYNL STHPDNCSRM IEGGGVSSLV GALKNEGVAE EAAGALALLV
610 620 630 640 650
RQSLGAEAIG KEDSAVAGLM GMMRCGTPRG KENAVAALLE LCRSGGAAVA
660 670 680 690 700
EKVLRAPAIA GLLQTLLFTG TKRARRKAAS LARVFQRREN AAMRSGVYGF
710 720
VGNTNGNRDG GFTTDVSVPI SISISVPVL
Length:729
Mass (Da):79,834
Last modified:June 1, 2001 - v1
Checksum:i206F96A0C6E9E482
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti571 – 5711I → T in AAL36401 (PubMed:14593172).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC068667 Genomic DNA. Translation: AAG51726.1.
CP002684 Genomic DNA. Translation: AEE31074.1.
AY064045 mRNA. Translation: AAL36401.1.
AY150512 mRNA. Translation: AAN13028.1.
PIRiA86416.
RefSeqiNP_174228.1. NM_102674.3.
UniGeneiAt.17411.
At.27415.

Genome annotation databases

EnsemblPlantsiAT1G29340.1; AT1G29340.1; AT1G29340.
GeneIDi839808.
GrameneiAT1G29340.1; AT1G29340.1; AT1G29340.
KEGGiath:AT1G29340.

Cross-referencesi

Web resourcesi

PlantsUBQ

A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC068667 Genomic DNA. Translation: AAG51726.1.
CP002684 Genomic DNA. Translation: AEE31074.1.
AY064045 mRNA. Translation: AAL36401.1.
AY150512 mRNA. Translation: AAN13028.1.
PIRiA86416.
RefSeqiNP_174228.1. NM_102674.3.
UniGeneiAt.17411.
At.27415.

3D structure databases

ProteinModelPortaliQ9C7R6.
SMRiQ9C7R6. Positions 306-377, 392-684.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9C7R6. 1 interaction.
STRINGi3702.AT1G29340.1.

Proteomic databases

PaxDbiQ9C7R6.
PRIDEiQ9C7R6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G29340.1; AT1G29340.1; AT1G29340.
GeneIDi839808.
GrameneiAT1G29340.1; AT1G29340.1; AT1G29340.
KEGGiath:AT1G29340.

Organism-specific databases

TAIRiAT1G29340.

Phylogenomic databases

eggNOGiENOG410ITMB. Eukaryota.
ENOG410YC2C. LUCA.
HOGENOMiHOG000238412.
InParanoidiQ9C7R6.
OMAiENRAYIA.
PhylomeDBiQ9C7R6.

Enzyme and pathway databases

UniPathwayiUPA00143.
BRENDAi2.3.2.B10. 399.

Miscellaneous databases

PROiQ9C7R6.

Gene expression databases

GenevisibleiQ9C7R6. AT.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
3.30.40.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
IPR003613. Ubox_domain.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF00514. Arm. 1 hit.
PF04564. U-box. 1 hit.
[Graphical view]
SMARTiSM00185. ARM. 5 hits.
SM00504. Ubox. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50176. ARM_REPEAT. 1 hit.
PS51698. U_BOX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. Cited for: GENE FAMILY ORGANIZATION, NOMENCLATURE.
  5. "A large complement of the predicted Arabidopsis ARM repeat proteins are members of the U-box E3 ubiquitin ligase family."
    Mudgil Y., Shiu S.-H., Stone S.L., Salt J.N., Goring D.R.
    Plant Physiol. 134:59-66(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY ORGANIZATION.
  6. "The E3 ubiquitin ligase activity of arabidopsis PLANT U-BOX17 and its functional tobacco homolog ACRE276 are required for cell death and defense."
    Yang C.-W., Gonzalez-Lamothe R., Ewan R.A., Rowland O., Yoshioka H., Shenton M., Ye H., O'Donnell E., Jones J.D.G., Sadanandom A.
    Plant Cell 18:1084-1098(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.

Entry informationi

Entry nameiPUB17_ARATH
AccessioniPrimary (citable) accession number: Q9C7R6
Secondary accession number(s): Q8VZK7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: June 1, 2001
Last modified: June 8, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.