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Protein

ABC transporter B family member 13

Gene

ABCB13

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi406 – 413ATP 1PROSITE-ProRule annotation8
Nucleotide bindingi1039 – 1046ATP 2PROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT1G27940-MONOMER
ReactomeiR-ATH-159418 Recycling of bile acids and salts
R-ATH-193368 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
R-ATH-382556 ABC-family proteins mediated transport

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter B family member 13
Short name:
ABC transporter ABCB.13
Short name:
AtABCB13
Alternative name(s):
P-glycoprotein 13
Putative multidrug resistance protein 15
Gene namesi
Name:ABCB13
Synonyms:MDR15, PGP13
Ordered Locus Names:At1g27940
ORF Names:F13K9.5
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G27940
TAIRilocus:2010464 AT1G27940

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei48 – 68HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei94 – 114HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei171 – 191HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei195 – 215HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei276 – 296HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei314 – 334HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei686 – 706HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei725 – 745HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei805 – 822HelicalPROSITE-ProRule annotationAdd BLAST18
Transmembranei828 – 848HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei913 – 933HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei947 – 967HelicalPROSITE-ProRule annotationAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002279261 – 1245ABC transporter B family member 13Add BLAST1245

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi77N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi351N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi391N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi778N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1008N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1106N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9C7F8
PRIDEiQ9C7F8

Expressioni

Gene expression databases

ExpressionAtlasiQ9C7F8 baseline and differential
GenevisibleiQ9C7F8 AT

Interactioni

Protein-protein interaction databases

BioGridi24922, 2 interactors
STRINGi3702.AT1G27940.1

Structurei

3D structure databases

ProteinModelPortaliQ9C7F8
SMRiQ9C7F8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini47 – 336ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST290
Domaini372 – 607ABC transporter 1PROSITE-ProRule annotationAdd BLAST236
Domaini681 – 969ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST289
Domaini1004 – 1240ABC transporter 2PROSITE-ProRule annotationAdd BLAST237

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi616 – 665Ser-richAdd BLAST50

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0055 Eukaryota
COG1132 LUCA
InParanoidiQ9C7F8
KOiK05658
OMAiNALMEGE
OrthoDBiEOG093601EV
PhylomeDBiQ9C7F8

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

Sequencei

Sequence statusi: Complete.

Q9C7F8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNTERSSNG NIQAETEAKE EKKNIKKESV SLMGLFSAAD KLDYFLMLLG
60 70 80 90 100
GLGACIHGAT LPLFFVFFGK MLDSLGNLST DPKAISSRVS QNALYLVYLG
110 120 130 140 150
LVNFVSAWIG VSCWMQTGER QTARLRINYL KSILAKDITF FDTEARDSNL
160 170 180 190 200
IFHISSDAIL VQDAIGDKTD HVLRYLSQFI AGFVIGFLSV WQLTLLTLGV
210 220 230 240 250
VPLIAIAGGG YAIVMSTISE KSETAYADAG KVAEEVMSQV RTVYAFVGEE
260 270 280 290 300
KAVKSYSNSL KKALKLGKRS GLAKGLGVGL TYSLLFCAWA LLLWYASLLV
310 320 330 340 350
RHGKTNGAKA FTTILNVIFS GFALGQAAPS LSAIAKGRVA AANIFRMIGN
360 370 380 390 400
NNSESSQRLD EGTTLQNVAG RIEFQKVSFA YPSRPNMVFE NLSFTIRSGK
410 420 430 440 450
TFAFVGPSGS GKSTIISMVQ RFYEPNSGEI LLDGNDIKSL KLKWFREQLG
460 470 480 490 500
LVSQEPALFA TTIASNILLG KENANMDQII EAAKAANADS FIKSLPNGYN
510 520 530 540 550
TQVGEGGTQL SGGQKQRIAI ARAVLRNPKI LLLDEATSAL DAESEKIVQQ
560 570 580 590 600
ALDNVMEKRT TIVVAHRLST IRNVDKIVVL RDGQVRETGS HSELMLRGGD
610 620 630 640 650
YATLVNCQET EPQENSRSIM SETCKSQAGS SSSRRVSSSR RTSSFRVDQE
660 670 680 690 700
KTKNDDSKKD FSSSSMIWEL IKLNSPEWPY ALLGSIGAVL AGAQTPLFSM
710 720 730 740 750
GIAYVLTAFY SPFPNVIKRD VEKVAIIFAG AGIVTAPIYL LQHYFYTLMG
760 770 780 790 800
ERLTSRVRLS LFSAILSNEI GWFDLDENNT GSLTSILAAD ATLVRSALAD
810 820 830 840 850
RLSTIVQNLS LTVTALALAF FYSWRVAAVV TACFPLLIAA SLTEQLFLKG
860 870 880 890 900
FGGDYTRAYS RATSVAREAI ANIRTVAAYG AEKQISEQFT CELSKPTKNA
910 920 930 940 950
FVRGHISGFG YGLSQFLAFC SYALGLWYVS VLINHKETNF GDSIKSFMVL
960 970 980 990 1000
IVTAFSVSET LALTPDIVKG TQALGSVFRV LHRETKISPD QPNSRMVSQV
1010 1020 1030 1040 1050
KGDIEFRNVS FVYPTRPEID IFKNLNLRVS AGKSLAVVGP SGSGKSTVIG
1060 1070 1080 1090 1100
LIMRFYDPSN GNLCIDGQDI KTLNLRSLRK KLALVQQEPA LFSTTIYENI
1110 1120 1130 1140 1150
KYGNENASEA EIMEAAKAAN AHEFIIKMEE GYKTHAGDKG VQLSGGQKQR
1160 1170 1180 1190 1200
VAIARAVLKD PSVLLLDEAT SALDTSSEKL VQEALDKLMK GRTTVLVAHR
1210 1220 1230 1240
LSTIRKADTV AVLHKGRVVE KGSHRELVSI PNGFYKQLTS LQEVL
Length:1,245
Mass (Da):135,776
Last modified:June 1, 2001 - v1
Checksum:iFDCE513FC3F14A1C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC069471 Genomic DNA Translation: AAG51482.1
CP002684 Genomic DNA Translation: AEE30893.1
PIRiG86404
RefSeqiNP_174115.1, NM_102559.2

Genome annotation databases

EnsemblPlantsiAT1G27940.1; AT1G27940.1; AT1G27940
GeneIDi839687
GrameneiAT1G27940.1; AT1G27940.1; AT1G27940
KEGGiath:AT1G27940

Similar proteinsi

Entry informationi

Entry nameiAB13B_ARATH
AccessioniPrimary (citable) accession number: Q9C7F8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: June 1, 2001
Last modified: April 25, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health